Drug : Sr8278

CTRP2 Name : SR8278

Dataset : All
Synonyms :
Targets : NR1D1
Pathways : antagonist of Rev-ErbAalpha

Information Cards

Click to show/hide information cards below or download all drug response information.

           
     

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including drug name, cell line name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Drug name Cellosaurus ID Original Dataset(s) Min Dose Max Dose Dose-response
SR8278 KE-39 CTRP2 0.0020 66.0000
SR8278 DMS454 CTRP2 0.0020 66.0000
SR8278 GCT CTRP2 0.0020 66.0000
SR8278 HCC2935 CTRP2 0.0020 66.0000
SR8278 HOP-62 CTRP2 0.0020 66.0000
SR8278 NCI-H747 CTRP2 0.0020 66.0000
SR8278 OVCAR-5 CTRP2 0.0020 66.0000
SR8278 SF268 CTRP2 0.0020 66.0000
SR8278 SF539 CTRP2 0.0020 66.0000
SR8278 TUHR14TKB CTRP2 0.5200 66.0000
SR8278 U-251MG CTRP2 0.0020 66.0000
SR8278 DMS53 CTRP2 0.0020 66.0000
SR8278 HEC-1-A CTRP2 0.0020 66.0000
SR8278 IGR-37 CTRP2 0.0020 66.0000
SR8278 KNS-62 CTRP2 0.0020 66.0000
SR8278 MDA-MB-157 CTRP2 0.0020 66.0000
SR8278 NCI-H1563 CTRP2 0.0020 66.0000
SR8278 OC314 CTRP2 0.0020 66.0000
SR8278 UO-31 CTRP2 0.0020 66.0000
SR8278 BICR56 CTRP2 0.0020 66.0000
SR8278 CAL-33 CTRP2 0.0020 66.0000
SR8278 CALU-1 CTRP2 0.0020 66.0000
SR8278 CAPAN-2 CTRP2 0.0020 66.0000
SR8278 DMS114 CTRP2 0.0020 66.0000
SR8278 EKVX CTRP2 0.0020 66.0000
SR8278 HCC1438 CTRP2 0.0020 66.0000
SR8278 HCT8 CTRP2 0.0020 66.0000
SR8278 HOP-92 CTRP2 0.5200 66.0000
SR8278 KYM-1 CTRP2 0.0020 66.0000
SR8278 KYSE-30 CTRP2 0.0020 66.0000
SR8278 KYSE-510 CTRP2 0.0020 66.0000
SR8278 L-428 CTRP2 0.0020 66.0000
SR8278 MDA-MB-361 CTRP2 0.5200 66.0000
SR8278 MFE-296 CTRP2 0.0020 66.0000
SR8278 NU-DHL-1 CTRP2 0.0020 66.0000
SR8278 SNB-75 CTRP2 0.0020 66.0000
SR8278 SNU-216 CTRP2 0.0020 66.0000
SR8278 BICR16 CTRP2 0.0020 66.0000
SR8278 F-36P CTRP2 0.0020 66.0000
SR8278 JJN-3 CTRP2 0.0020 66.0000
SR8278 KASUMI-2 CTRP2 0.0020 66.0000
SR8278 KMS-20 CTRP2 0.0020 66.0000
SR8278 KYSE-150 CTRP2 0.0020 66.0000
SR8278 OCI-AML-5 CTRP2 0.0020 66.0000
SR8278 PANC08.13 CTRP2 0.0020 66.0000
SR8278 SNU-601 CTRP2 0.0020 66.0000
SR8278 SNU-C4 CTRP2 0.0020 66.0000
SR8278 T-47D CTRP2 0.0020 66.0000
SR8278 TE-14 CTRP2 0.0020 66.0000
SR8278 U266B1 CTRP2 0.0020 66.0000
SR8278 42-MG-BA CTRP2 0.0020 66.0000
SR8278 BT139 CTRP2 0.0020 66.0000
SR8278 BT159 CTRP2 0.0020 66.0000
SR8278 BT187 CTRP2 0.0020 66.0000
SR8278 BT228 CTRP2 0.0020 66.0000
SR8278 BT231 CTRP2 0.0020 66.0000
SR8278 BT239 CTRP2 0.0020 66.0000
SR8278 BT-474 CTRP2 0.0020 66.0000
SR8278 COV434 CTRP2 0.0020 66.0000
SR8278 G-292CLONEA141B1 CTRP2 0.0020 66.0000
SR8278 HS766T CTRP2 0.0020 66.0000
SR8278 KMRC-3 CTRP2 0.0020 66.0000
SR8278 M-07E CTRP2 0.0020 66.0000
SR8278 NCI-H1651 CTRP2 0.0020 66.0000
SR8278 SK-BR-3 CTRP2 0.0020 66.0000
SR8278 A-204 CTRP2 0.0020 66.0000
SR8278 AML-193 CTRP2 0.0020 66.0000
SR8278 HGC-27 CTRP2 0.0020 66.0000
SR8278 HS578BST CTRP2 0.0020 66.0000
SR8278 MALME-3M CTRP2 0.0020 66.0000
SR8278 HS688(A).T CTRP2 0.0020 66.0000
SR8278 HUT78 CTRP2 0.0020 66.0000
SR8278 NCI-H1793 CTRP2 0.0020 66.0000
SR8278 SCC-4 CTRP2 0.0020 66.0000
SR8278 SK-ES-1 CTRP2 0.0020 66.0000
SR8278 HS888.T CTRP2 0.0020 66.0000
SR8278 MDA-MB-453 CTRP2 0.0020 66.0000
SR8278 SAOS-2 CTRP2 0.0020 66.0000
SR8278 U-BLC1 CTRP2 0.0020 66.0000
SR8278 NCI-H1694 CTRP2 0.0020 66.0000
SR8278 SEM CTRP2 0.0020 66.0000
SR8278 HS822.T CTRP2 0.0020 66.0000
SR8278 HS940.T CTRP2 0.0020 66.0000
SR8278 KMBC-2 CTRP2 0.0020 66.0000
SR8278 RCC10RGB CTRP2 0.0020 66.0000
SR8278 SK-N-BE(2) CTRP2 0.0020 66.0000
SR8278 AU565 CTRP2 0.0020 66.0000
SR8278 COLO320 CTRP2 0.0020 66.0000
SR8278 MDA-MB-415 CTRP2 0.0020 66.0000
SR8278 PANC10.05 CTRP2 0.0020 66.0000
SR8278 BT131 CTRP2 0.0020 66.0000
SR8278 BT147 CTRP2 0.0020 66.0000
SR8278 BT172 CTRP2 0.0020 66.0000
SR8278 BT216 CTRP2 0.0020 66.0000
SR8278 BT232 CTRP2 0.0020 66.0000
SR8278 BT245 CTRP2 0.0020 66.0000
SR8278 BT271 CTRP2 0.0020 66.0000
SR8278 BT286 CTRP2 0.0020 66.0000
SR8278 BT320 CTRP2 0.0020 66.0000
SR8278 BT328 CTRP2 0.0020 66.0000
SR8278 BT330 CTRP2 0.0020 66.0000
SR8278 BT333 CTRP2 0.0020 66.0000
SR8278 BT340 CTRP2 0.0020 66.0000
SR8278 BT359 CTRP2 0.0020 66.0000
SR8278 BT422 CTRP2 0.0020 66.0000
SR8278 BT428 CTRP2 0.0020 66.0000
SR8278 BT440 CTRP2 0.0020 66.0000
SR8278 BT444 CTRP2 0.0020 66.0000
SR8278 BT482 CTRP2 0.0020 66.0000
SR8278 BT498 CTRP2 0.0020 66.0000
SR8278 BT504 CTRP2 0.0020 66.0000
SR8278 2004 CTRP2 0.0020 66.0000
SR8278 BT-12 CTRP2 0.0020 66.0000
SR8278 BT-16 CTRP2 0.0020 66.0000
SR8278 SW982 CTRP2 0.0020 66.0000
SR8278 SYO-1 CTRP2 0.0020 66.0000
SR8278 TM87-16 CTRP2 0.0020 66.0000
SR8278 TTC-709 CTRP2 0.0020 66.0000

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Cell lines with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Cell lines with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Cell lines with highest and lowest AUC

Associated Genes (Mutation)

Genes with the largest and lowest Racksum’s effect sizes, calculated by comparing IC50 between the mutant and wide type cell lines using cell lines from pancan data.

Associated Genes (Gene Expression)

Genes with the highest and lowest Spearman correlations, calculated by comparing gene expression and IC50 across cell lines from pancan data.