Cell Line : YMB-1-E

Cellosaurus Index : CVCL_2815
Cellosaurus ID : YMB-1-E

CCLE Name : YMB1E_BREAST
GDSC1 Name , GDSC2 Name : YMB-1-E

Cancer Type : breast
Dataset : All

Drug Response Information

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Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including cell line name, drug name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Cellosaurus ID Drug Name Original Dataset(s) Min Dose Max Dose Dose-response
YMB-1-E 5-Fluorouracil GDSC1,GDSC2 0.0200 32.0000
YMB-1-E A-83-01 GDSC1 0.0200 5.1200
YMB-1-E ABT737 GDSC2 0.0100 10.0000
YMB-1-E ACY-1215 GDSC1 0.0781 20.0000
YMB-1-E Afatinib GDSC2 0.0040 4.0000
YMB-1-E Afuresertib GDSC2 0.0100 10.0000
YMB-1-E AGI-5198 GDSC2 0.0100 10.0000
YMB-1-E AGI-6780 GDSC1,GDSC2 0.0020 10.0000
YMB-1-E AGK-2 GDSC2 0.0040 4.0000
YMB-1-E AKT inhibitor VIII GDSC1 0.0400 10.2400
YMB-1-E Alectinib GDSC1 0.0200 5.1200
YMB-1-E Alisertib GDSC1,GDSC2 0.0100 10.0000
YMB-1-E Alpelisib GDSC2 0.0100 10.0000
YMB-1-E AMG-319 GDSC2 0.0100 10.0000
YMB-1-E Amuvatinib GDSC1 0.0781 20.0000
YMB-1-E Apitolisib GDSC1 0.0781 20.0000
YMB-1-E AR-42 GDSC1 0.0200 5.1200
YMB-1-E Ara-G GDSC1 0.0200 5.1200
YMB-1-E ARRY-520 GDSC1 0.0010 0.2560
YMB-1-E AS605240 GDSC1 0.0781 20.0000
YMB-1-E AST-1306 GDSC1 0.0781 20.0000
YMB-1-E AT-7519 GDSC1 0.0400 10.2400
YMB-1-E AT13148 GDSC2 0.0080 8.0000
YMB-1-E AT7867 GDSC1 0.0781 20.0000
YMB-1-E Avagacestat GDSC1,GDSC2 0.0100 10.2400
YMB-1-E Axitinib GDSC2 0.0100 10.0000
YMB-1-E AZ6102 GDSC2 0.0100 10.0000
YMB-1-E AZ960 GDSC2 0.0100 10.0000
YMB-1-E AZD3759 GDSC2 0.0010 1.0000
YMB-1-E AZD4547 GDSC2 0.0100 10.0000
YMB-1-E AZD5363 GDSC2 0.0100 10.0000
YMB-1-E AZD5582 GDSC2 0.0100 10.0000
YMB-1-E AZD6482 GDSC2 0.0100 10.0000
YMB-1-E AZD6738 GDSC2 0.0100 10.0000
YMB-1-E AZD7762 GDSC2 0.0010 2.0000
YMB-1-E AZD8186 GDSC2 0.0100 10.0000
YMB-1-E BAM7 GDSC1 0.0781 20.0000
YMB-1-E Belinostat GDSC1 0.0781 20.0000
YMB-1-E BI-2536 GDSC2 0.0005 0.5000
YMB-1-E BIBF-1120 GDSC1 0.0781 20.0000
YMB-1-E BIBR-1532 GDSC2 0.0100 10.0000
YMB-1-E Bicalutamide GDSC2 0.0100 10.0000
YMB-1-E BIX02189 GDSC1 0.0781 20.0000
YMB-1-E BMS-345541 GDSC1,GDSC2 0.0100 16.0000
YMB-1-E BMS-536924 GDSC2 0.0100 10.0000
YMB-1-E BMS-754807 GDSC2 0.0100 10.0000
YMB-1-E Bortezomib GDSC2 0.0000 0.0200
YMB-1-E Bosutinib GDSC2 0.0020 2.0000
YMB-1-E Brivanib, BMS-540215 GDSC1 0.0781 20.0000
YMB-1-E Buparlisib GDSC2 0.0100 10.0000
YMB-1-E BX-912 GDSC1 0.0400 10.2400
YMB-1-E BX795 GDSC2 0.0100 10.0000
YMB-1-E C-75 GDSC1 0.0781 20.0000
YMB-1-E Cabozantinib GDSC1 0.0200 5.1200
YMB-1-E Camptothecin GDSC2 0.0001 0.1000
YMB-1-E CAP-232, TT-232, TLN-232 GDSC1 0.0781 20.0000
YMB-1-E CAY10566 GDSC1 0.0100 2.5600
YMB-1-E CAY10603 GDSC1 0.0781 20.0000
YMB-1-E CCT-018159 GDSC2 0.0100 10.0000
YMB-1-E CCT007093 GDSC2 0.0100 10.0000
YMB-1-E CD532 GDSC1 0.0200 5.1200
YMB-1-E Cediranib GDSC2 0.0100 10.0000
YMB-1-E CHIR-99021 GDSC2 0.0100 10.0000
YMB-1-E CI-1033 GDSC1 0.0781 20.0000
YMB-1-E CP466722 GDSC1 0.0625 16.0000
YMB-1-E CP724714 GDSC1 0.0400 10.2400
YMB-1-E CPI-613 GDSC1 1.0000 256.0000
YMB-1-E Crizotinib GDSC2 0.0040 8.0000
YMB-1-E CUDC-101 GDSC1 0.0200 5.1200
YMB-1-E CX-5461 GDSC1 0.0400 10.2400
YMB-1-E Cyclophosphamide GDSC2 0.0100 10.0000
YMB-1-E CZC24832 GDSC2 0.0100 10.0000
YMB-1-E Dabrafenib GDSC2 0.0100 10.0000
YMB-1-E Dactinomycin GDSC2 0.0008 0.8000
YMB-1-E Dactolisib GDSC2 0.0003 0.2500
YMB-1-E Daporinad GDSC2 0.0010 1.0000
YMB-1-E Dasatinib GDSC2 0.0020 2.0000
YMB-1-E Dinaciclib GDSC2 0.0010 1.0000
YMB-1-E Docetaxel GDSC2 0.0000 0.0125
YMB-1-E Doramapimod GDSC2 0.0100 10.0000
YMB-1-E eEF2K Inhibitor, A-484954 GDSC1 0.0781 20.0000
YMB-1-E EHT-1864 GDSC2 0.0100 10.0000
YMB-1-E Elesclomol GDSC2 0.0002 0.2000
YMB-1-E Entinostat GDSC2 0.0100 10.0000
YMB-1-E Entospletinib GDSC2 0.0100 10.0000
YMB-1-E Enzastaurin GDSC1 0.0781 20.0000
YMB-1-E Epirubicin GDSC2 0.0100 10.0000
YMB-1-E EPZ004777 GDSC2 0.0100 10.0000
YMB-1-E EPZ5676 GDSC2 0.0100 10.0000
YMB-1-E Erlotinib GDSC2 0.0100 10.0000
YMB-1-E ETP-45835 GDSC1 0.0781 20.0000
YMB-1-E Fedratinib GDSC1 0.0400 10.2400
YMB-1-E Flavopiridol GDSC1 0.0100 2.5600
YMB-1-E FMK GDSC1 0.0781 20.0000
YMB-1-E Foretinib GDSC1,GDSC2 0.0100 10.0000
YMB-1-E FR-180204 GDSC1 0.0781 20.0000
YMB-1-E FTY-720 GDSC1 0.0781 20.0000
YMB-1-E Fulvestrant GDSC2 0.0010 1.0000
YMB-1-E GDC0810 GDSC2 0.0100 10.0000
YMB-1-E Gefitinib GDSC2 0.0020 2.0000
YMB-1-E Gemcitabine GDSC2 0.0100 10.0000
YMB-1-E Genentech Cpd 10 GDSC1 0.0400 10.2400
YMB-1-E GNE-317 GDSC2 0.0100 10.0000
YMB-1-E GSK1059615 GDSC1 0.0781 20.0000
YMB-1-E GSK1070916 GDSC1 0.0100 2.5600
YMB-1-E GSK1904529A GDSC2 0.0050 5.0000
YMB-1-E GSK2578215A GDSC2 0.0100 10.0000
YMB-1-E GSK2606414 GDSC2 0.0100 10.0000
YMB-1-E GSK269962A GDSC2 0.0100 10.0000
YMB-1-E GSK343 GDSC2 0.0010 1.0000
YMB-1-E GSK429286A GDSC1 0.0781 20.0000
YMB-1-E GSK591 GDSC2 0.0100 10.0000
YMB-1-E GSK690693 GDSC1 0.0400 10.2400
YMB-1-E GW-2580 GDSC1 0.0781 20.0000
YMB-1-E GW441756 GDSC2 0.0020 2.0000
YMB-1-E I-BET-762 GDSC1,GDSC2 0.0100 20.0000
YMB-1-E I-BRD9 GDSC2 0.0100 10.0000
YMB-1-E Ibrutinib GDSC2 0.0100 10.0000
YMB-1-E IC-87114 GDSC1 0.0781 20.0000
YMB-1-E Idelalisib GDSC1 0.0781 20.0000
YMB-1-E IMD-0354 GDSC1 0.0781 20.0000
YMB-1-E IOX2 GDSC2 0.0005 0.5000
YMB-1-E Ipatasertib GDSC2 0.0100 10.0000
YMB-1-E Irinotecan GDSC2 0.0050 5.0000
YMB-1-E Ispinesib Mesylate GDSC1 0.0005 0.1280
YMB-1-E IWP-2 GDSC2 0.0010 1.0000
YMB-1-E JNJ38877605 GDSC1 0.0781 20.0000
YMB-1-E JNK Inhibitor VIII GDSC2 0.0100 10.0000
YMB-1-E JQ1 GDSC2 0.0100 10.0000
YMB-1-E JW-7-24-1 GDSC1 0.0400 10.2400
YMB-1-E kb NB 142-70 GDSC1 0.0781 20.0000
YMB-1-E KIN001-042 GDSC1 0.0400 10.2400
YMB-1-E KIN001-236 GDSC1 0.0400 10.2400
YMB-1-E KIN001-244 GDSC1 0.0781 20.0000
YMB-1-E KIN001-260 GDSC1 0.0781 20.0000
YMB-1-E KIN001-266 GDSC1 0.0781 20.0000
YMB-1-E KIN001-270 GDSC1 0.0781 20.0000
YMB-1-E Kobe2602 GDSC1 0.0781 20.0000
YMB-1-E KRAS (G12C) Inhibitor-12 GDSC2 0.0200 20.0000
YMB-1-E KU-55933 GDSC2 0.0100 10.0000
YMB-1-E Lapatinib GDSC2 0.0100 10.0000
YMB-1-E LCL161 GDSC1,GDSC2 0.0100 20.0000
YMB-1-E LDN-193189 GDSC1 0.0400 10.2400
YMB-1-E Leflunomide GDSC2 0.1001 100.0000
YMB-1-E Lenalidomide GDSC2 0.0100 10.0000
YMB-1-E Lestaurtinib GDSC2 0.0020 2.0000
YMB-1-E LGK974 GDSC1,GDSC2 0.0020 10.0000
YMB-1-E LIMK1 inhibitor BMS4 GDSC1 0.0781 20.0000
YMB-1-E Linifanib GDSC1 0.0040 1.0240
YMB-1-E Linsitinib GDSC2 0.0100 10.0000
YMB-1-E LJI308 GDSC2 0.0100 10.0000
YMB-1-E Luminespib GDSC2 0.0003 0.2500
YMB-1-E LY2109761 GDSC2 0.0050 5.0000
YMB-1-E Masitinib GDSC1 0.0781 20.0000
YMB-1-E MetAP2 Inhibitor, A832234 GDSC1 0.0100 2.5600
YMB-1-E Methotrexate GDSC2 0.0010 1.0000
YMB-1-E MG-132 GDSC2 0.0040 4.0000
YMB-1-E MIM1 GDSC1 0.1562 40.0000
YMB-1-E MIRA-1 GDSC2 0.0100 10.0000
YMB-1-E Mirin GDSC2 0.1001 100.0000
YMB-1-E MK-1775 GDSC2 0.0100 10.0000
YMB-1-E MK-2206 GDSC2 0.0100 10.0000
YMB-1-E MK-8776 GDSC2 0.0050 5.0000
YMB-1-E ML323 GDSC2 0.0200 20.0000
YMB-1-E MN-64 GDSC2 0.0100 10.0000
YMB-1-E Motesanib GDSC2 0.0100 10.0000
YMB-1-E MPS-1-IN-1 GDSC1 0.0781 20.0000
YMB-1-E Navitoclax GDSC2 0.0020 2.0000
YMB-1-E NG-25 GDSC1 0.0400 10.2400
YMB-1-E Nilotinib GDSC2 0.0100 10.0000
YMB-1-E Niraparib GDSC2 0.0100 10.0000
YMB-1-E NPK76-II-72-1 GDSC1 0.0400 10.2400
YMB-1-E NSC-207895 GDSC1 0.0781 20.0000
YMB-1-E NSC319726 GDSC1 0.0040 1.0240
YMB-1-E NU7441 GDSC2 0.0100 10.0000
YMB-1-E Nutlin-3a GDSC2 0.0100 10.0000
YMB-1-E NVP-ADW742 GDSC2 0.0100 10.0000
YMB-1-E NVP-BHG712 GDSC1 0.0400 10.2400
YMB-1-E OF-1 GDSC2 0.0100 10.0000
YMB-1-E Olaparib GDSC2 0.0100 10.0000
YMB-1-E Omipalisib GDSC1 0.0005 0.1280
YMB-1-E OSI-027 GDSC1,GDSC2 0.0100 20.0000
YMB-1-E OSI-930 GDSC1 0.0400 10.2400
YMB-1-E Osimertinib GDSC2 0.0010 1.0000
YMB-1-E OTX015 GDSC2 0.0100 10.0000
YMB-1-E Oxaliplatin GDSC2 0.0100 10.0000
YMB-1-E P22077 GDSC2 0.0100 10.0000
YMB-1-E Paclitaxel GDSC2 0.0001 0.1000
YMB-1-E Palbociclib GDSC2 0.0040 4.0000
YMB-1-E Panobinostat GDSC1 0.0040 1.0240
YMB-1-E PCI-34051 GDSC2 0.0100 10.0000
YMB-1-E PD0325901 GDSC2 0.0025 2.5000
YMB-1-E PD173074 GDSC2 0.0100 10.0000
YMB-1-E Pelitinib GDSC1 0.0098 2.5000
YMB-1-E Pemetrexed GDSC1 0.0400 10.2400
YMB-1-E Pevonedistat GDSC2 0.0100 10.0000
YMB-1-E PF-00299804 GDSC1 0.0781 20.0000
YMB-1-E PF-4708671 GDSC2 0.0100 10.0000
YMB-1-E PFI-1 GDSC2 0.0100 10.0000
YMB-1-E PFI3 GDSC2 0.0100 10.0000
YMB-1-E PHA-793887 GDSC1 0.0400 10.2400
YMB-1-E Phenformin GDSC1 15.6250 4000.0000
YMB-1-E PI-103 GDSC1 0.0400 10.2400
YMB-1-E Picolinici-acid GDSC2 0.0100 10.0000
YMB-1-E Pictilisib GDSC2 0.0040 4.0000
YMB-1-E PIK-93 GDSC1 0.0781 20.0000
YMB-1-E Pilaralisib GDSC1 0.0781 20.0000
YMB-1-E Piperlongumine GDSC2 0.0100 10.0000
YMB-1-E PLX-4720 GDSC2 0.0100 10.0000
YMB-1-E PRIMA-1MET GDSC2 0.0300 30.0000
YMB-1-E PRT062607 GDSC2 0.0100 10.0000
YMB-1-E Pyridostatin GDSC2 0.0100 10.0000
YMB-1-E QL-X-138 GDSC1 0.0400 10.2400
YMB-1-E QL-XI-92 GDSC1 0.0400 10.2400
YMB-1-E QL-XII-47 GDSC1 0.0400 10.2400
YMB-1-E Quizartinib GDSC1 0.0040 1.0240
YMB-1-E Rapamycin GDSC2 0.0001 0.1000
YMB-1-E Refametinib GDSC2 0.0100 10.0000
YMB-1-E Ribociclib GDSC2 0.0020 2.0000
YMB-1-E RO-3306 GDSC2 0.0100 10.0000
YMB-1-E RU-SKI 43 GDSC1 0.0781 20.0000
YMB-1-E Rucaparib GDSC2 0.0050 5.0000
YMB-1-E Ruxolitinib GDSC1,GDSC2 0.0100 10.0000
YMB-1-E RVX-208 GDSC2 0.0100 10.0000
YMB-1-E Sabutoclax GDSC2 0.0100 10.0000
YMB-1-E Sapitinib GDSC2 0.0050 5.0000
YMB-1-E Savolitinib GDSC2 0.0010 1.0000
YMB-1-E SB216763 GDSC2 0.0100 10.0000
YMB-1-E SB505124 GDSC1,GDSC2 0.0100 20.0000
YMB-1-E SB52334 GDSC1 0.0781 20.0000
YMB-1-E SB590885 GDSC2 0.0050 5.0000
YMB-1-E SCH772984 GDSC2 0.0050 5.0000
YMB-1-E Selisistat GDSC1 0.0781 20.0000
YMB-1-E Selumetinib GDSC2 0.0100 10.0000
YMB-1-E Sepantronium bromide GDSC1,GDSC2 0.0100 10.0000
YMB-1-E Serdemetan GDSC2 0.0100 10.0000
YMB-1-E SGC0946 GDSC2 0.0005 0.5000
YMB-1-E SL0101 GDSC2 0.0100 10.0000
YMB-1-E SN-38 GDSC2 0.0100 10.0000
YMB-1-E SNX-2112 GDSC1 0.0100 2.5600
YMB-1-E Sorafenib GDSC2 0.0100 10.0000
YMB-1-E Sphingosine Kinase 1 Inhibitor II GDSC1 0.0100 2.5600
YMB-1-E Staurosporine GDSC2 0.0078 2.0000
YMB-1-E STF-62247 GDSC1 0.0400 10.2400
YMB-1-E SU11274 GDSC1 0.0400 10.2400
YMB-1-E T0901317 GDSC1 0.0400 10.2400
YMB-1-E TAK-715 GDSC1 0.0781 20.0000
YMB-1-E Talazoparib GDSC2 0.0100 10.0000
YMB-1-E Tamoxifen GDSC2 0.0100 10.0000
YMB-1-E Tanespimycin GDSC2 0.0010 1.0000
YMB-1-E Taselisib GDSC2 0.0100 10.0000
YMB-1-E Telomerase Inhibitor IX GDSC2 0.0100 10.0000
YMB-1-E Temozolomide GDSC2 0.0300 30.0000
YMB-1-E Temsirolimus GDSC2 0.0010 1.0000
YMB-1-E Tenovin-6 GDSC1 0.0781 20.0000
YMB-1-E THZ-2-102-1 GDSC1 0.0098 2.5000
YMB-1-E THZ-2-49 GDSC1 0.0781 20.0000
YMB-1-E Tivozanib GDSC1 0.0005 0.1280
YMB-1-E TL-1-85 GDSC1 0.0400 10.2400
YMB-1-E TL-2-105 GDSC1 0.0400 10.2400
YMB-1-E Torin 2 GDSC1 0.0781 20.0000
YMB-1-E Tozasertib GDSC2 0.0050 5.0000
YMB-1-E TPCA-1 GDSC1 0.0781 20.0000
YMB-1-E Trametinib GDSC2 0.0010 1.0000
YMB-1-E Tretinoin GDSC2 0.0100 10.0000
YMB-1-E Trichostatin A GDSC1 0.0040 1.0240
YMB-1-E Tubastatin A GDSC1 0.0781 20.0000
YMB-1-E TWS119 GDSC1 0.0781 20.0000
YMB-1-E Ulixertinib GDSC2 0.0100 10.0000
YMB-1-E UNC0638 GDSC1 0.1562 40.0000
YMB-1-E Uprosertib GDSC2 0.0100 10.0000
YMB-1-E VE-822 GDSC2 0.0050 5.0000
YMB-1-E VE821 GDSC2 0.0100 10.0000
YMB-1-E Veliparib GDSC2 0.0100 10.0000
YMB-1-E Venetoclax GDSC2 0.0010 1.0000
YMB-1-E Venotoclax GDSC1 0.0010 0.2560
YMB-1-E Vinorelbine GDSC2 0.0001 0.1000
YMB-1-E Vismodegib GDSC2 0.0100 10.0000
YMB-1-E VNLG-124 GDSC1 0.0200 5.1200
YMB-1-E Vorinostat GDSC2 0.0100 10.0000
YMB-1-E Voxtalisib GDSC1 0.0781 20.0000
YMB-1-E VX-11e GDSC1,GDSC2 0.0100 10.0000
YMB-1-E Wee1 Inhibitor GDSC2 0.0100 10.0000
YMB-1-E WEHI-539 GDSC2 0.0100 10.0000
YMB-1-E WHI-P97 GDSC1 0.0400 10.2400
YMB-1-E WIKI4 GDSC2 0.0100 10.0000
YMB-1-E Wnt-C59 GDSC1,GDSC2 0.0020 10.0000
YMB-1-E WYE-125132 GDSC1 0.0400 10.2400
YMB-1-E WZ3105 GDSC1 0.0050 1.2800
YMB-1-E WZ4003 GDSC2 0.0100 10.0000
YMB-1-E XAV939 GDSC2 0.0050 5.0000
YMB-1-E XMD13-2 GDSC1 0.0400 10.2400
YMB-1-E XMD14-99 GDSC1 0.0400 10.2400
YMB-1-E XMD15-27 GDSC1 0.0400 10.2400
YMB-1-E Y-39983 GDSC1 0.0781 20.0000
YMB-1-E YK-4-279 GDSC2 0.0100 10.0000
YMB-1-E YM201636 GDSC1 0.0200 5.1200
YMB-1-E Zibotentan GDSC1 0.0781 20.0000
YMB-1-E ZM447439 GDSC2 0.0100 10.0000
YMB-1-E ZSTK474 GDSC1 0.0200 5.1200

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Drugs with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Drugs with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Drugs with highest and lowest AUC