Cell Line : SC-1

Cellosaurus Index : CVCL_1888
Cellosaurus ID : SC-1

CCLE Name : SC1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE
GDSC1 Name : SC-1

Cancer Type : haematopoietic_and_lymphoid_tissue
Dataset : All

Drug Response Information

Click to show/hide information cards below or download all drug response information.

           

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

:

Experimental information

Experimental information from All dataset, including cell line name, drug name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Cellosaurus ID Drug Name Original Dataset(s) Min Dose Max Dose Dose-response
SC-1 (5Z)-7-Oxozeaenol GDSC1 0.0391 10.0000
SC-1 5-Fluorouracil GDSC1 0.1250 32.0000
SC-1 965-D2 GDSC1 0.0391 10.0000
SC-1 993-D2 GDSC1 0.0391 10.0000
SC-1 A-83-01 GDSC1 0.0781 20.0000
SC-1 ACY-1215 GDSC1 0.0781 20.0000
SC-1 Afatinib GDSC1 0.0020 10.0000
SC-1 AGI-6780 GDSC1 0.0020 0.5120
SC-1 AICA Ribonucleotide GDSC1 7.8125 2000.0000
SC-1 AKT inhibitor VIII GDSC1 0.0100 10.2400
SC-1 Alectinib GDSC1 0.0200 5.1200
SC-1 Alisertib GDSC1 0.0100 2.5600
SC-1 Amuvatinib GDSC1 0.0781 20.0000
SC-1 Apitolisib GDSC1 0.0781 20.0000
SC-1 AR-42 GDSC1 0.0200 5.1200
SC-1 Ara-G GDSC1 0.0781 20.0000
SC-1 ARRY-520 GDSC1 0.0010 0.2560
SC-1 AS601245 GDSC1 0.0312 8.0000
SC-1 AS605240 GDSC1 0.0781 20.0000
SC-1 AST-1306 GDSC1 0.0781 20.0000
SC-1 AT-7519 GDSC1 0.0400 10.2400
SC-1 AT7867 GDSC1 0.0781 20.0000
SC-1 Avagacestat GDSC1 0.0195 10.2400
SC-1 Axitinib GDSC1 0.0078 2.0000
SC-1 AZ20 GDSC1 0.0391 10.0000
SC-1 AZ628 GDSC1 0.0156 4.0000
SC-1 AZD1208 GDSC1 0.0391 10.0000
SC-1 AZD1332 GDSC1 0.0391 10.0000
SC-1 AZD1480 GDSC1 0.0098 2.5000
SC-1 AZD2014 GDSC1 0.0391 10.0000
SC-1 AZD3514 GDSC1 0.0391 10.0000
SC-1 AZD4547 GDSC1 0.0039 10.0000
SC-1 AZD4877 GDSC1 0.0002 0.0390
SC-1 AZD5438 GDSC1 0.0391 10.0000
SC-1 AZD5582 GDSC1 0.0391 10.0000
SC-1 AZD6094 GDSC1 0.0098 2.5000
SC-1 AZD6482 GDSC1 0.0195 5.1200
SC-1 AZD6738 GDSC1 0.0391 10.0000
SC-1 AZD7762 GDSC1 0.0078 10.0000
SC-1 AZD7969 GDSC1 0.0391 10.0000
SC-1 AZD8055 GDSC1 0.0078 2.0000
SC-1 AZD8186 GDSC1 0.0098 2.5000
SC-1 AZD8835 GDSC1 0.0391 10.0000
SC-1 AZD8931 GDSC1 0.0391 10.0000
SC-1 BAM7 GDSC1 0.0781 20.0000
SC-1 BAY ACCi GDSC1 0.0391 10.0000
SC-1 BAY AKT1 GDSC1 0.0391 10.0000
SC-1 BAY-61-3606 GDSC1 0.0312 8.0000
SC-1 BAY-HDAC11_1 GDSC1 0.0391 10.0000
SC-1 BAY-HDAC11_2 GDSC1 0.0391 10.0000
SC-1 BAY-HDAC11_4 GDSC1 0.0391 10.0000
SC-1 BAY-MPS-combo 2 (paclitaxel 1 uM) GDSC1 0.0039 1.0000
SC-1 BAY-MPS-combo-1 (paclitaxel 5 uM) GDSC1 0.0039 1.0000
SC-1 BAY-MPS1 GDSC1 0.0117 3.0000
SC-1 Belinostat GDSC1 0.0781 20.0000
SC-1 Bexarotene GDSC1 0.0312 8.0000
SC-1 BIBF-1120 GDSC1 0.0781 20.0000
SC-1 Bicalutamide GDSC1 0.0040 10.0000
SC-1 BIX02189 GDSC1 0.0781 20.0000
SC-1 Bleomycin GDSC1 0.2500 64.0000
SC-1 Bleomycin (10 uM) GDSC1 0.0391 10.0000
SC-1 Bleomycin (50 uM) GDSC1 0.1953 50.0000
SC-1 BMS-345541 GDSC1 0.0625 16.0000
SC-1 BMS-536924 GDSC1 0.0156 4.0000
SC-1 BMS-754807 GDSC1 0.0100 2.5600
SC-1 Bortezomib GDSC1 0.0001 0.0200
SC-1 Bosutinib GDSC1 0.0078 2.0000
SC-1 BPTES GDSC1 0.0391 10.0000
SC-1 Brivanib, BMS-540215 GDSC1 0.0781 20.0000
SC-1 Bryostatin 1 GDSC1 0.0000 0.0080
SC-1 BX-912 GDSC1 0.0400 10.2400
SC-1 BX795 GDSC1 0.0195 5.0000
SC-1 C-75 GDSC1 0.0781 20.0000
SC-1 Cabozantinib GDSC1 0.0200 5.1200
SC-1 CAP-232, TT-232, TLN-232 GDSC1 0.0781 20.0000
SC-1 Capivasertib GDSC1 0.1172 30.0000
SC-1 CAY10566 GDSC1 0.0100 2.5600
SC-1 CAY10603 GDSC1 0.0781 20.0000
SC-1 CCT-018159 GDSC1 0.0391 10.0000
SC-1 CCT007093 GDSC1 0.0258 6.6000
SC-1 CCT245232 GDSC1 0.0008 0.2000
SC-1 CCT245467 GDSC1 0.0008 0.2000
SC-1 CD532 GDSC1 0.0200 5.1200
SC-1 Cetuximab GDSC1 0.2570 65.8000
SC-1 CHIR-99021 GDSC1 0.0100 10.0000
SC-1 CI-1033 GDSC1 0.0781 20.0000
SC-1 CI-1040 GDSC1 0.0391 10.0000
SC-1 Cisplatin GDSC1 0.0117 10.0000
SC-1 CP466722 GDSC1 0.0625 16.0000
SC-1 CP724714 GDSC1 0.0400 10.2400
SC-1 CPI-613 GDSC1 1.0000 256.0000
SC-1 CRT0105446 GDSC1 0.0391 10.0000
SC-1 CRT0105950 GDSC1 0.0391 10.0000
SC-1 CRT0160829 GDSC1 0.0781 20.0000
SC-1 CUDC-101 GDSC1 0.0200 5.1200
SC-1 CX-5461 GDSC1 0.0400 10.2400
SC-1 Cyclopamine GDSC1 0.0625 16.0000
SC-1 Cytarabine GDSC1 0.0078 2.0000
SC-1 Dabrafenib GDSC1 0.0391 10.0000
SC-1 Dacinostat GDSC1 0.0040 1.0240
SC-1 Dactolisib GDSC1 0.0010 0.2500
SC-1 Daporinad GDSC1 0.0039 1.0000
SC-1 DMOG GDSC1 15.6250 4000.0000
SC-1 Docetaxel GDSC1 0.0000 0.0125
SC-1 Doramapimod GDSC1 0.0391 10.0000
SC-1 Doxorubicin GDSC1 0.0040 5.0000
SC-1 Dyrk1b_0191 GDSC1 0.0391 10.0000
SC-1 eEF2K Inhibitor, A-484954 GDSC1 0.0781 20.0000
SC-1 EHT-1864 GDSC1 0.0391 10.0000
SC-1 Elesclomol GDSC1 0.0008 0.2000
SC-1 Embelin GDSC1 0.1250 32.0000
SC-1 Entinostat GDSC1 0.0195 5.0000
SC-1 Enzastaurin GDSC1 0.0781 20.0000
SC-1 EphB4_9721 GDSC1 0.0391 10.0000
SC-1 Epothilone B GDSC1 0.0001 0.0320
SC-1 Erlotinib GDSC1 0.0078 2.0000
SC-1 Etoposide GDSC1 0.0625 16.0000
SC-1 ETP-45835 GDSC1 0.0781 20.0000
SC-1 Fedratinib GDSC1 0.0400 10.2400
SC-1 FEN1_3940 GDSC1 0.0391 10.0000
SC-1 FGFR_0939 GDSC1 0.0098 2.5000
SC-1 FGFR_3831 GDSC1 0.0391 10.0000
SC-1 FH535 GDSC1 0.1250 32.0000
SC-1 Flavopiridol GDSC1 0.0100 2.5600
SC-1 FMK GDSC1 0.0781 20.0000
SC-1 Foretinib GDSC1 0.0200 5.1200
SC-1 FR-180204 GDSC1 0.0781 20.0000
SC-1 FS106 GDSC1 0.0391 10.0000
SC-1 FS112 GDSC1 0.0195 5.0000
SC-1 FTI-277 GDSC1 0.0040 1.0240
SC-1 FTY-720 GDSC1 0.0781 20.0000
SC-1 Fulvestrant GDSC1 0.0391 10.0000
SC-1 FY012 GDSC1 0.0391 10.0000
SC-1 FY026 GDSC1 0.0391 10.0000
SC-1 FY069 GDSC1 0.0391 10.0000
SC-1 Gefitinib GDSC1 0.0020 0.5000
SC-1 Gemcitabine GDSC1 0.0002 1.0240
SC-1 Genentech Cpd 10 GDSC1 0.0400 10.2400
SC-1 GSK-J4 GDSC1 0.1172 30.0000
SC-1 GSK1059615 GDSC1 0.0781 20.0000
SC-1 GSK1070916 GDSC1 0.0100 2.5600
SC-1 GSK1904529A GDSC1 0.0040 1.0240
SC-1 GSK269962A GDSC1 0.0098 5.0000
SC-1 GSK319347A GDSC1 0.0195 5.0000
SC-1 GSK429286A GDSC1 0.0781 20.0000
SC-1 GSK650394 GDSC1 0.0625 16.0000
SC-1 GSK690693 GDSC1 0.0400 10.2400
SC-1 GW-2580 GDSC1 0.0781 20.0000
SC-1 GW441756 GDSC1 0.0078 2.0000
SC-1 HG6-64-1 GDSC1 0.0200 5.1200
SC-1 I-BET-762 GDSC1 0.0781 20.0000
SC-1 I-BET151 GDSC1 0.0391 10.0000
SC-1 I-CBP112 GDSC1 0.0391 10.0000
SC-1 IAP_5620 GDSC1 0.0391 10.0000
SC-1 IAP_7638 GDSC1 0.0391 10.0000
SC-1 IC-87114 GDSC1 0.0781 20.0000
SC-1 ICL1100013 GDSC1 0.0781 20.0000
SC-1 Idelalisib GDSC1 0.0781 20.0000
SC-1 IGFR_3801 GDSC1 0.0391 10.0000
SC-1 IMD-0354 GDSC1 0.0781 20.0000
SC-1 IOX2 GDSC1 0.0004 0.1000
SC-1 IPA-3 GDSC1 0.1250 32.0000
SC-1 Ispinesib Mesylate GDSC1 0.0005 0.1280
SC-1 JAK1_3715 GDSC1 0.0391 10.0000
SC-1 JAK3_7406 GDSC1 0.0391 10.0000
SC-1 JNJ38877605 GDSC1 0.0781 20.0000
SC-1 JNK Inhibitor VIII GDSC1 0.0391 10.0000
SC-1 JNK-9L GDSC1 0.0200 5.1200
SC-1 JQ1 GDSC1 0.0039 2.5600
SC-1 JQ12 GDSC1 0.0200 5.1200
SC-1 JW-7-24-1 GDSC1 0.0400 10.2400
SC-1 kb NB 142-70 GDSC1 0.0781 20.0000
SC-1 KIN001-042 GDSC1 0.0400 10.2400
SC-1 KIN001-236 GDSC1 0.0400 10.2400
SC-1 KIN001-244 GDSC1 0.0781 20.0000
SC-1 KIN001-260 GDSC1 0.0781 20.0000
SC-1 KIN001-266 GDSC1 0.0781 20.0000
SC-1 KIN001-270 GDSC1 0.0781 20.0000
SC-1 Kobe2602 GDSC1 0.0781 20.0000
SC-1 KU-55933 GDSC1 0.0391 10.0000
SC-1 KU-60019 GDSC1 0.0391 10.0000
SC-1 Lapatinib GDSC1 0.0078 2.0000
SC-1 LCL161 GDSC1 0.0100 2.5600
SC-1 LDN-193189 GDSC1 0.0400 10.2400
SC-1 Lenalidomide GDSC1 0.0195 5.0000
SC-1 Lestaurtinib GDSC1 0.0078 2.0000
SC-1 LFM-A13 GDSC1 0.0625 16.0000
SC-1 LGK974 GDSC1 0.0100 2.5600
SC-1 LIMK1 inhibitor BMS4 GDSC1 0.0781 20.0000
SC-1 Linifanib GDSC1 0.0040 1.0240
SC-1 Linsitinib GDSC1 0.0100 2.5600
SC-1 Luminespib GDSC1 0.0010 0.2560
SC-1 Masitinib GDSC1 0.0781 20.0000
SC-1 MCT1_6447 GDSC1 0.0391 10.0000
SC-1 MCT4_1422 GDSC1 0.0391 10.0000
SC-1 MetAP2 Inhibitor, A832234 GDSC1 0.0100 2.5600
SC-1 Methotrexate GDSC1 0.0008 0.2000
SC-1 MG-132 GDSC1 0.0039 1.0000
SC-1 Midostaurin GDSC1 0.0020 0.5120
SC-1 MIM1 GDSC1 0.1562 40.0000
SC-1 Mirin GDSC1 0.3906 100.0000
SC-1 Mitomycin-C GDSC1 0.0625 16.0000
SC-1 MK-2206 GDSC1 0.0156 4.0000
SC-1 Motesanib GDSC1 0.0078 2.0000
SC-1 MPS-1-IN-1 GDSC1 0.0781 20.0000
SC-1 N22899-6-C1 GDSC1 0.0391 10.0000
SC-1 N23918-95-7 GDSC1 0.0391 10.0000
SC-1 N24798-49-A1 GDSC1 0.0391 10.0000
SC-1 Navitoclax GDSC1 0.0078 2.0000
SC-1 NG-25 GDSC1 0.0400 10.2400
SC-1 Nilotinib GDSC1 0.0078 2.0000
SC-1 NPK76-II-72-1 GDSC1 0.0400 10.2400
SC-1 NSC-207895 GDSC1 0.0781 20.0000
SC-1 NSC-87877 GDSC1 0.0625 16.0000
SC-1 NSC319726 GDSC1 0.0010 0.2560
SC-1 NU7441 GDSC1 0.0078 2.0000
SC-1 Nutlin-3a GDSC1 0.0312 8.0000
SC-1 NVP-BHG712 GDSC1 0.0400 10.2400
SC-1 Obatoclax Mesylate GDSC1 0.0625 16.0000
SC-1 Olaparib GDSC1 0.0195 10.0000
SC-1 Omipalisib GDSC1 0.0005 0.1280
SC-1 OSI-027 GDSC1 0.0781 20.0000
SC-1 OSI-930 GDSC1 0.0400 10.2400
SC-1 OSU-03012 GDSC1 0.0625 16.0000
SC-1 PAC-1 GDSC1 0.0100 2.5600
SC-1 Palbociclib GDSC1 0.0156 4.0000
SC-1 Panobinostat GDSC1 0.0040 1.0240
SC-1 PARP_0108 GDSC1 0.0098 2.5000
SC-1 PARP_9482 GDSC1 0.0098 2.5000
SC-1 PARP_9495 GDSC1 0.0098 2.5000
SC-1 Parthenolide GDSC1 0.0195 5.0000
SC-1 Pazopanib GDSC1 0.0312 8.0000
SC-1 PD0325901 GDSC1 0.0010 0.2500
SC-1 PD173074 GDSC1 0.0078 2.0000
SC-1 Pelitinib GDSC1 0.0098 2.5000
SC-1 Pemetrexed GDSC1 0.0100 2.5600
SC-1 Pevonedistat GDSC1 0.0039 1.0000
SC-1 PF-00299804 GDSC1 0.0781 20.0000
SC-1 PF-4708671 GDSC1 0.0391 10.0000
SC-1 PF-562271 GDSC1 0.0100 2.5600
SC-1 PFI-1 GDSC1 0.0391 10.0000
SC-1 PFI3 GDSC1 0.0391 10.0000
SC-1 PHA-793887 GDSC1 0.0400 10.2400
SC-1 Phenformin GDSC1 15.6250 4000.0000
SC-1 PI-103 GDSC1 0.0400 10.2400
SC-1 PI3Ka_4409 GDSC1 0.0391 10.0000
SC-1 Pictilisib GDSC1 0.0156 4.0000
SC-1 PIK-93 GDSC1 0.0781 20.0000
SC-1 Pilaralisib GDSC1 0.0781 20.0000
SC-1 Piperlongumine GDSC1 0.0391 10.0000
SC-1 PLK_6522 GDSC1 0.0024 0.6250
SC-1 PLX-4720 GDSC1 0.0391 10.0000
SC-1 Ponatinib GDSC1 0.0020 0.5120
SC-1 Pyrimethamine GDSC1 0.0781 20.0000
SC-1 QL-X-138 GDSC1 0.0400 10.2400
SC-1 QL-XI-92 GDSC1 0.0400 10.2400
SC-1 QL-XII-47 GDSC1 0.0400 10.2400
SC-1 QS11 GDSC1 0.0400 10.2400
SC-1 Quizartinib GDSC1 0.0040 1.0240
SC-1 RAF_9304 GDSC1 0.0391 10.0000
SC-1 Refametinib GDSC1 0.0195 5.0000
SC-1 RO-3306 GDSC1 0.0195 5.0000
SC-1 rTRAIL GDSC1 0.0004 0.1000
SC-1 RU-SKI 43 GDSC1 0.0781 20.0000
SC-1 Rucaparib GDSC1 0.0195 5.0000
SC-1 Ruxolitinib GDSC1 0.0205 5.2400
SC-1 Salubrinal GDSC1 0.0625 16.0000
SC-1 SB216763 GDSC1 0.0391 10.0000
SC-1 SB505124 GDSC1 0.0391 20.0000
SC-1 SB52334 GDSC1 0.0781 20.0000
SC-1 SB590885 GDSC1 0.0195 5.0000
SC-1 Seliciclib GDSC1 0.0625 16.0000
SC-1 Selisistat GDSC1 0.0781 20.0000
SC-1 Selumetinib GDSC1 0.0156 4.0000
SC-1 Sepantronium bromide GDSC1 0.0200 5.1200
SC-1 Serdemetan GDSC1 0.0391 10.0000
SC-1 SGC0946 GDSC1 0.0020 0.5000
SC-1 Shikonin GDSC1 0.0625 16.0000
SC-1 SL0101 GDSC1 0.0391 10.0000
SC-1 SN-38 GDSC1 0.0002 0.1000
SC-1 SNX-2112 GDSC1 0.0100 2.5600
SC-1 Sorafenib GDSC1 0.0156 4.0000
SC-1 Sphingosine Kinase 1 Inhibitor II GDSC1 0.0100 2.5600
SC-1 STF-62247 GDSC1 0.0400 10.2400
SC-1 SU11274 GDSC1 0.0400 10.2400
SC-1 T0901317 GDSC1 0.0400 10.2400
SC-1 TAK-715 GDSC1 0.0781 20.0000
SC-1 Talazoparib GDSC1 0.0391 10.0000
SC-1 Tamoxifen GDSC1 0.0195 5.0000
SC-1 Tanespimycin GDSC1 0.0039 1.0000
SC-1 TANK_1366 GDSC1 0.0098 2.5000
SC-1 Temozolomide GDSC1 0.1172 30.0000
SC-1 Temsirolimus GDSC1 0.0008 0.2000
SC-1 Tenovin-6 GDSC1 0.0781 20.0000
SC-1 TGX221 GDSC1 0.0391 10.0000
SC-1 Thapsigargin GDSC1 0.0020 0.5120
SC-1 THZ-2-102-1 GDSC1 0.0098 2.5000
SC-1 THZ-2-49 GDSC1 0.0781 20.0000
SC-1 Tipifarnib GDSC1 0.0625 16.0000
SC-1 Tivozanib GDSC1 0.0005 0.1280
SC-1 TL-1-85 GDSC1 0.0400 10.2400
SC-1 TL-2-105 GDSC1 0.0400 10.2400
SC-1 Torin 2 GDSC1 0.0781 20.0000
SC-1 TPCA-1 GDSC1 0.0781 20.0000
SC-1 Trametinib GDSC1 0.0039 1.0000
SC-1 Tretinoin GDSC1 0.0391 10.0000
SC-1 Trichostatin A GDSC1 0.0040 1.0240
SC-1 TTK_3146 GDSC1 0.0391 10.0000
SC-1 Tubastatin A GDSC1 0.0781 20.0000
SC-1 TW 37 GDSC1 0.0195 5.0000
SC-1 TWS119 GDSC1 0.0781 20.0000
SC-1 UNC0638 GDSC1 0.0781 40.0000
SC-1 UNC0642 GDSC1 0.0020 0.5000
SC-1 UNC1215 GDSC1 0.0039 1.0000
SC-1 Veliparib GDSC1 0.0195 5.0000
SC-1 Venotoclax GDSC1 0.0010 0.2560
SC-1 Vinblastine GDSC1 0.0004 0.1000
SC-1 Vinorelbine GDSC1 0.0003 0.0640
SC-1 Vismodegib GDSC1 0.0391 10.0000
SC-1 VNLG-124 GDSC1 0.0200 5.1200
SC-1 Vorinostat GDSC1 0.0391 10.0000
SC-1 Voxtalisib GDSC1 0.0781 20.0000
SC-1 VX-11e GDSC1 0.0200 5.1200
SC-1 VX-702 GDSC1 0.0078 2.0000
SC-1 Wee1 Inhibitor GDSC1 0.0078 2.0000
SC-1 WHI-P97 GDSC1 0.0400 10.2400
SC-1 Wnt-C59 GDSC1 0.0100 2.5600
SC-1 WYE-125132 GDSC1 0.0400 10.2400
SC-1 WZ3105 GDSC1 0.0050 1.2800
SC-1 XAV939 GDSC1 0.0195 5.0000
SC-1 XMD13-2 GDSC1 0.0400 10.2400
SC-1 XMD14-99 GDSC1 0.0400 10.2400
SC-1 XMD15-27 GDSC1 0.0400 10.2400
SC-1 XMD8-85 GDSC1 0.0312 8.0000
SC-1 Y-39983 GDSC1 0.0781 20.0000
SC-1 YK-4-279 GDSC1 0.0391 10.0000
SC-1 YM201636 GDSC1 0.0200 5.1200
SC-1 Zibotentan GDSC1 0.0781 20.0000
SC-1 ZL049 GDSC1 0.0391 10.0000
SC-1 ZL109 GDSC1 0.0391 10.0000
SC-1 ZM447439 GDSC1 0.0156 4.0000
SC-1 ZSTK474 GDSC1 0.0200 5.1200

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Drugs with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Drugs with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Drugs with highest and lowest AUC