Cell Line : NCI-H250

Cellosaurus Index : CVCL_1554
Cellosaurus ID : NCI-H250

GDSC1 Name , GDSC2 Name : NCI-H250
CCLE Name : NCIH250_LUNG

Cancer Type : lung
Dataset : All

Drug Response Information

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Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including cell line name, drug name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Cellosaurus ID Drug Name Original Dataset(s) Min Dose Max Dose Dose-response
NCI-H250 123138 GDSC2 0.0010 1.0000
NCI-H250 123829 GDSC2 0.0030 3.0000
NCI-H250 150412 GDSC2 0.0030 3.0000
NCI-H250 5-Fluorouracil GDSC2 0.0200 20.0000
NCI-H250 50869 GDSC2 0.0030 3.0000
NCI-H250 615590 GDSC2 0.0030 3.0000
NCI-H250 630600 GDSC2 0.0030 3.0000
NCI-H250 667880 GDSC2 0.0030 3.0000
NCI-H250 720427 GDSC2 0.0030 3.0000
NCI-H250 729189 GDSC2 0.0030 3.0000
NCI-H250 741909 GDSC2 0.0010 1.0000
NCI-H250 743380 GDSC2 0.0010 1.0000
NCI-H250 765771 GDSC2 0.0030 3.0000
NCI-H250 776928 GDSC2 0.0300 30.0000
NCI-H250 ABT737 GDSC2 0.0100 10.0000
NCI-H250 Acetalax GDSC2 0.0300 30.0000
NCI-H250 Afatinib GDSC2 0.0020 4.0000
NCI-H250 Afuresertib GDSC2 0.0100 10.0000
NCI-H250 AGI-5198 GDSC2 0.0100 10.0000
NCI-H250 AGI-6780 GDSC2 0.0100 10.0000
NCI-H250 AGK-2 GDSC2 0.0040 4.0000
NCI-H250 Alisertib GDSC2 0.0020 10.0000
NCI-H250 Alpelisib GDSC2 0.0050 10.0000
NCI-H250 AMG-319 GDSC2 0.0100 10.0000
NCI-H250 AT13148 GDSC2 0.0080 8.0000
NCI-H250 Avagacestat GDSC2 0.0100 10.0000
NCI-H250 Axitinib GDSC2 0.0100 10.0000
NCI-H250 AZ6102 GDSC2 0.0100 10.0000
NCI-H250 AZ960 GDSC2 0.0100 10.0000
NCI-H250 AZD1208 GDSC2 0.0100 10.0000
NCI-H250 AZD1332 GDSC2 0.0100 10.0000
NCI-H250 AZD2014 GDSC2 0.0100 10.0000
NCI-H250 AZD3759 GDSC2 0.0010 1.0000
NCI-H250 AZD4547 GDSC2 0.0100 10.0000
NCI-H250 AZD5153 GDSC2 0.0100 10.0000
NCI-H250 AZD5363 GDSC2 0.0100 10.0000
NCI-H250 AZD5438 GDSC2 0.0100 10.0000
NCI-H250 AZD5582 GDSC2 0.0100 10.0000
NCI-H250 AZD5991 GDSC2 0.0100 10.0000
NCI-H250 AZD6482 GDSC2 0.0100 10.0000
NCI-H250 AZD6738 GDSC2 0.0100 10.0000
NCI-H250 AZD7762 GDSC2 0.0010 2.0000
NCI-H250 AZD8186 GDSC2 0.0100 10.0000
NCI-H250 BDF00022089a GDSC2 0.0050 5.0000
NCI-H250 BDILV000379a GDSC2 0.0050 5.0000
NCI-H250 BDOCA000347a GDSC2 0.0020 2.0000
NCI-H250 BEN GDSC2 0.0300 30.0000
NCI-H250 BI-2536 GDSC2 0.0005 0.5000
NCI-H250 BIBR-1532 GDSC2 0.0100 10.0000
NCI-H250 Bicalutamide GDSC2 0.0100 10.0000
NCI-H250 Bleomycin GDSC2 0.0020 2.0000
NCI-H250 BMS-345541 GDSC2 0.0100 10.0000
NCI-H250 BMS-536924 GDSC2 0.0100 10.0000
NCI-H250 BMS-754807 GDSC2 0.0100 10.0000
NCI-H250 Bortezomib GDSC2 0.0000 0.0200
NCI-H250 Bosutinib GDSC2 0.0020 2.0000
NCI-H250 Bromosporine GDSC2 0.0020 2.0000
NCI-H250 Buparlisib GDSC2 0.0100 10.0000
NCI-H250 BX795 GDSC2 0.0100 10.0000
NCI-H250 Camptothecin GDSC2 0.0001 0.1000
NCI-H250 Carmustine GDSC2 0.0300 30.0000
NCI-H250 CCT-018159 GDSC2 0.0100 10.0000
NCI-H250 CCT007093 GDSC2 0.0100 10.0000
NCI-H250 CDK9_5038 GDSC2 0.0030 3.0000
NCI-H250 CDK9_5576 GDSC2 0.0100 10.0000
NCI-H250 Cediranib GDSC2 0.0100 10.0000
NCI-H250 CHIR-99021 GDSC2 0.0100 10.0000
NCI-H250 Crizotinib GDSC2 0.0010 8.0000
NCI-H250 Cyclophosphamide GDSC2 0.0100 10.0000
NCI-H250 CZC24832 GDSC2 0.0100 10.0000
NCI-H250 Dabrafenib GDSC2 0.0100 10.0000
NCI-H250 Dacarbazine GDSC2 0.0200 20.0000
NCI-H250 Dactinomycin GDSC2 0.0000 0.8000
NCI-H250 Dactolisib GDSC2 0.0003 0.2500
NCI-H250 Daporinad GDSC2 0.0010 1.0000
NCI-H250 Dasatinib GDSC2 0.0020 2.0000
NCI-H250 Dihydrorotenone GDSC2 0.0010 1.0000
NCI-H250 Dinaciclib GDSC2 0.0010 1.0000
NCI-H250 Docetaxel GDSC2 0.0000 3.0000
NCI-H250 Doramapimod GDSC2 0.0100 10.0000
NCI-H250 Eg5_9814 GDSC2 0.0001 0.1000
NCI-H250 EHT-1864 GDSC2 0.0100 10.0000
NCI-H250 Elephantin GDSC2 0.0200 20.0000
NCI-H250 Elesclomol GDSC2 0.0002 0.2000
NCI-H250 Entinostat GDSC2 0.0100 10.0000
NCI-H250 Entospletinib GDSC2 0.0100 10.0000
NCI-H250 Epirubicin GDSC2 0.0100 10.0000
NCI-H250 EPZ004777 GDSC2 0.0100 10.0000
NCI-H250 EPZ5676 GDSC2 0.0100 10.0000
NCI-H250 ERK_2440 GDSC2 0.0100 10.0000
NCI-H250 ERK_6604 GDSC2 0.0100 10.0000
NCI-H250 Erlotinib GDSC2 0.0100 10.0000
NCI-H250 Fludarabine GDSC2 0.0200 20.0000
NCI-H250 Foretinib GDSC2 0.0100 10.0000
NCI-H250 Fulvestrant GDSC2 0.0010 10.0000
NCI-H250 Gallibiscoquinazole GDSC2 0.0010 1.0000
NCI-H250 GDC0810 GDSC2 0.0100 10.0000
NCI-H250 Gefitinib GDSC2 0.0020 2.0000
NCI-H250 Gemcitabine GDSC2 0.0100 10.0000
NCI-H250 GNE-317 GDSC2 0.0100 10.0000
NCI-H250 GSK-LSD1 GDSC2 0.0010 1.0000
NCI-H250 GSK1904529A GDSC2 0.0050 10.0000
NCI-H250 GSK2110183B GDSC2 0.0030 3.0000
NCI-H250 GSK2256098C GDSC2 0.0030 3.0000
NCI-H250 GSK2276186C GDSC2 0.0100 10.0000
NCI-H250 GSK2578215A GDSC2 0.0100 10.0000
NCI-H250 GSK2606414 GDSC2 0.0100 10.0000
NCI-H250 GSK269962A GDSC2 0.0100 10.0000
NCI-H250 GSK2801 GDSC2 0.0100 10.0000
NCI-H250 GSK2830371A GDSC2 0.0030 10.0000
NCI-H250 GSK3337463A GDSC2 0.0100 10.0000
NCI-H250 GSK343 GDSC2 0.0010 1.0000
NCI-H250 GSK591 GDSC2 0.0100 10.0000
NCI-H250 GSK626616AC GDSC2 0.0001 0.1000
NCI-H250 GW441756 GDSC2 0.0020 2.0000
NCI-H250 I-BET-762 GDSC2 0.0100 10.0000
NCI-H250 I-BRD9 GDSC2 0.0100 10.0000
NCI-H250 IAP_5620 GDSC2 0.0100 10.0000
NCI-H250 Ibrutinib GDSC2 0.0100 10.0000
NCI-H250 IGF1R_3801 GDSC2 0.0100 10.0000
NCI-H250 IOX2 GDSC2 0.0005 0.5000
NCI-H250 Ipatasertib GDSC2 0.0100 10.0000
NCI-H250 IRAK4_4710 GDSC2 0.0100 10.0000
NCI-H250 Irinotecan GDSC2 0.0050 5.0000
NCI-H250 IWP-2 GDSC2 0.0010 1.0000
NCI-H250 JAK_8517 GDSC2 0.0100 10.0000
NCI-H250 JAK1_8709 GDSC2 0.0100 10.0000
NCI-H250 JNK Inhibitor VIII GDSC2 0.0100 10.0000
NCI-H250 JQ1 GDSC2 0.0100 10.0000
NCI-H250 KRAS (G12C) Inhibitor-12 GDSC2 0.0200 20.0000
NCI-H250 KU-55933 GDSC2 0.0100 10.0000
NCI-H250 L-Oxonoreleagnine GDSC2 0.0030 3.0000
NCI-H250 Lapatinib GDSC2 0.0100 10.0000
NCI-H250 LCL161 GDSC2 0.0100 10.0000
NCI-H250 Leflunomide GDSC2 0.1001 100.0000
NCI-H250 Lenalidomide GDSC2 0.0100 10.0000
NCI-H250 Lestaurtinib GDSC2 0.0020 2.0000
NCI-H250 LGK974 GDSC2 0.0100 10.0000
NCI-H250 Linsitinib GDSC2 0.0025 10.0000
NCI-H250 LJI308 GDSC2 0.0100 10.0000
NCI-H250 LMB_AB1 GDSC2 0.0100 10.0000
NCI-H250 LMB_AB2 GDSC2 0.0100 10.0000
NCI-H250 LMB_AB3 GDSC2 0.0100 10.0000
NCI-H250 LMP744 GDSC2 0.0030 3.0000
NCI-H250 Luminespib GDSC2 0.0003 0.2500
NCI-H250 LY2109761 GDSC2 0.0050 10.0000
NCI-H250 Methotrexate GDSC2 0.0010 1.0000
NCI-H250 MG-132 GDSC2 0.0040 4.0000
NCI-H250 MIRA-1 GDSC2 0.0100 10.0000
NCI-H250 Mirin GDSC2 0.1001 100.0000
NCI-H250 Mitoxantrone GDSC2 0.0030 3.0000
NCI-H250 MK-1775 GDSC2 0.0100 10.0000
NCI-H250 MK-2206 GDSC2 0.0100 10.0000
NCI-H250 MK-8776 GDSC2 0.0050 5.0000
NCI-H250 ML323 GDSC2 0.0200 20.0000
NCI-H250 MN-64 GDSC2 0.0100 10.0000
NCI-H250 Motesanib GDSC2 0.0100 10.0000
NCI-H250 Navitoclax GDSC2 0.0020 2.0000
NCI-H250 Nelarabine GDSC2 0.0200 20.0000
NCI-H250 Nilotinib GDSC2 0.0100 10.0000
NCI-H250 Niraparib GDSC2 0.0100 10.0000
NCI-H250 NU7441 GDSC2 0.0100 10.0000
NCI-H250 Nutlin-3a GDSC2 0.0100 10.0000
NCI-H250 NVP-ADW742 GDSC2 0.0100 10.0000
NCI-H250 Obatoclax Mesylate GDSC2 0.0100 10.0000
NCI-H250 OF-1 GDSC2 0.0100 10.0000
NCI-H250 Olaparib GDSC2 0.0100 10.0000
NCI-H250 OSI-027 GDSC2 0.0100 10.0000
NCI-H250 Osimertinib GDSC2 0.0010 1.0000
NCI-H250 OTX015 GDSC2 0.0100 10.0000
NCI-H250 Oxaliplatin GDSC2 0.0100 20.0000
NCI-H250 P22077 GDSC2 0.0100 10.0000
NCI-H250 Paclitaxel GDSC2 0.0001 0.1000
NCI-H250 PAK_5339 GDSC2 0.0300 30.0000
NCI-H250 Palbociclib GDSC2 0.0040 4.0000
NCI-H250 Parthenolide GDSC1 0.0195 5.0000
NCI-H250 PCI-34051 GDSC2 0.0100 10.0000
NCI-H250 PD0325901 GDSC2 0.0003 2.5000
NCI-H250 PD173074 GDSC2 0.0100 10.0000
NCI-H250 Pevonedistat GDSC2 0.0100 10.0000
NCI-H250 PF-4708671 GDSC2 0.0100 10.0000
NCI-H250 PFI-1 GDSC2 0.0100 10.0000
NCI-H250 PFI3 GDSC2 0.0100 10.0000
NCI-H250 Picolinici-acid GDSC2 0.0100 10.0000
NCI-H250 Pictilisib GDSC2 0.0040 4.0000
NCI-H250 Piperlongumine GDSC2 0.0100 10.0000
NCI-H250 PLX-4720 GDSC2 0.0100 10.0000
NCI-H250 Podophyllotoxin bromide GDSC2 0.0010 1.0000
NCI-H250 PRIMA-1MET GDSC2 0.0300 30.0000
NCI-H250 PRT062607 GDSC2 0.0100 10.0000
NCI-H250 Pyridostatin GDSC2 0.0100 10.0000
NCI-H250 Rapamycin GDSC2 0.0001 0.1000
NCI-H250 Refametinib GDSC2 0.0100 10.0000
NCI-H250 Ribociclib GDSC2 0.0020 2.0000
NCI-H250 RO-3306 GDSC2 0.0100 10.0000
NCI-H250 Romidepsin GDSC2 0.0000 0.0100
NCI-H250 Rucaparib GDSC2 0.0050 5.0000
NCI-H250 Ruxolitinib GDSC2 0.0100 10.0000
NCI-H250 RVX-208 GDSC2 0.0100 10.0000
NCI-H250 Sabutoclax GDSC2 0.0100 10.0000
NCI-H250 Sapitinib GDSC2 0.0050 5.0000
NCI-H250 Savolitinib GDSC2 0.0010 1.0000
NCI-H250 SB216763 GDSC2 0.0100 10.0000
NCI-H250 SB505124 GDSC2 0.0100 10.0000
NCI-H250 SB590885 GDSC2 0.0050 5.0000
NCI-H250 SCH772984 GDSC2 0.0050 5.0000
NCI-H250 Schweinfurthin A GDSC2 0.0010 1.0000
NCI-H250 Selumetinib GDSC2 0.0100 10.0000
NCI-H250 Sepantronium bromide GDSC2 0.0100 10.0000
NCI-H250 Serdemetan GDSC2 0.0100 10.0000
NCI-H250 SGC-CBP30 GDSC2 0.0050 5.0000
NCI-H250 SGC0946 GDSC2 0.0005 0.5000
NCI-H250 Sinularin GDSC2 0.0030 3.0000
NCI-H250 SL0101 GDSC2 0.0100 10.0000
NCI-H250 SN-38 GDSC2 0.0100 10.0000
NCI-H250 Sorafenib GDSC2 0.0100 10.0000
NCI-H250 Staurosporine GDSC2 0.0078 2.0000
NCI-H250 TAF1_5496 GDSC2 0.0100 10.0000
NCI-H250 Talazoparib GDSC2 0.0100 10.0000
NCI-H250 Tamoxifen GDSC2 0.0100 10.0000
NCI-H250 Tanespimycin GDSC2 0.0010 1.0000
NCI-H250 Taselisib GDSC2 0.0040 10.0000
NCI-H250 Telomerase Inhibitor IX GDSC2 0.0100 10.0000
NCI-H250 Temozolomide GDSC2 0.0300 30.0000
NCI-H250 Temsirolimus GDSC2 0.0010 1.0000
NCI-H250 Teniposide GDSC2 0.0030 3.0000
NCI-H250 Topotecan GDSC2 0.0030 3.0000
NCI-H250 Tozasertib GDSC2 0.0050 5.0000
NCI-H250 Trametinib GDSC2 0.0010 1.0000
NCI-H250 Tretinoin GDSC2 0.0100 10.0000
NCI-H250 Ulixertinib GDSC2 0.0100 10.0000
NCI-H250 ULK1_4989 GDSC2 0.0300 30.0000
NCI-H250 Uprosertib GDSC2 0.0100 10.0000
NCI-H250 VE-822 GDSC2 0.0050 5.0000
NCI-H250 VE821 GDSC2 0.0100 10.0000
NCI-H250 Veliparib GDSC2 0.0100 10.0000
NCI-H250 Venetoclax GDSC2 0.0010 1.0000
NCI-H250 Vincristine GDSC2 0.0030 3.0000
NCI-H250 Vinorelbine GDSC2 0.0001 0.1000
NCI-H250 Vismodegib GDSC2 0.0100 10.0000
NCI-H250 Vorinostat GDSC2 0.0100 10.0000
NCI-H250 VSP34_8731 GDSC2 0.0300 30.0000
NCI-H250 VX-11e GDSC2 0.0100 10.0000
NCI-H250 Wee1 Inhibitor GDSC2 0.0100 10.0000
NCI-H250 WEHI-539 GDSC2 0.0100 10.0000
NCI-H250 WIKI4 GDSC2 0.0100 10.0000
NCI-H250 Wnt-C59 GDSC2 0.0100 10.0000
NCI-H250 WZ4003 GDSC2 0.0100 10.0000
NCI-H250 XAV939 GDSC2 0.0050 10.0000
NCI-H250 YK-4-279 GDSC2 0.0100 10.0000
NCI-H250 ZM447439 GDSC2 0.0100 10.0000
NCI-H250 Zoledronate GDSC2 0.0020 2.0000

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Drugs with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Drugs with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Drugs with highest and lowest AUC