Cell Line : PCI-38

Cellosaurus Index : CVCL_M471
Cellosaurus ID : PCI-38

CCLE Name : PCI38_UPPER_AERODIGESTIVE_TRACT
GDSC1 Name : PCI-38

Cancer Type : upper_aerodigestive_tract
Dataset : All

Drug Response Information

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Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including cell line name, drug name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Cellosaurus ID Drug Name Original Dataset(s) Min Dose Max Dose Dose-response
PCI-38 (5Z)-7-Oxozeaenol GDSC1 0.0391 10.0000
PCI-38 5-Fluorouracil GDSC1 0.1250 32.0000
PCI-38 965-D2 GDSC1 0.0391 10.0000
PCI-38 993-D2 GDSC1 0.0391 10.0000
PCI-38 A-83-01 GDSC1 0.0781 20.0000
PCI-38 ACY-1215 GDSC1 0.0781 20.0000
PCI-38 Afatinib GDSC1 0.0020 10.0000
PCI-38 AGI-6780 GDSC1 0.0020 0.5120
PCI-38 AICA Ribonucleotide GDSC1 7.8125 2000.0000
PCI-38 AKT inhibitor VIII GDSC1 0.0100 10.2400
PCI-38 Alectinib GDSC1 0.0200 5.1200
PCI-38 Alisertib GDSC1 0.0100 2.5600
PCI-38 Amuvatinib GDSC1 0.0781 20.0000
PCI-38 Apitolisib GDSC1 0.0781 20.0000
PCI-38 AR-42 GDSC1 0.0200 5.1200
PCI-38 Ara-G GDSC1 0.0781 20.0000
PCI-38 ARRY-520 GDSC1 0.0010 0.2560
PCI-38 AS601245 GDSC1 0.0312 8.0000
PCI-38 AS605240 GDSC1 0.0781 20.0000
PCI-38 AST-1306 GDSC1 0.0781 20.0000
PCI-38 AT-7519 GDSC1 0.0400 10.2400
PCI-38 AT7867 GDSC1 0.0781 20.0000
PCI-38 Avagacestat GDSC1 0.0195 10.2400
PCI-38 Axitinib GDSC1 0.0078 2.0000
PCI-38 AZ20 GDSC1 0.0391 10.0000
PCI-38 AZD1208 GDSC1 0.0391 10.0000
PCI-38 AZD1332 GDSC1 0.0391 10.0000
PCI-38 AZD1480 GDSC1 0.0098 2.5000
PCI-38 AZD2014 GDSC1 0.0391 10.0000
PCI-38 AZD3514 GDSC1 0.0391 10.0000
PCI-38 AZD4547 GDSC1 0.0039 10.0000
PCI-38 AZD4877 GDSC1 0.0002 0.0390
PCI-38 AZD5438 GDSC1 0.0391 10.0000
PCI-38 AZD5582 GDSC1 0.0391 10.0000
PCI-38 AZD6094 GDSC1 0.0098 2.5000
PCI-38 AZD6482 GDSC1 0.0195 5.1200
PCI-38 AZD6738 GDSC1 0.0391 10.0000
PCI-38 AZD7762 GDSC1 0.0078 10.0000
PCI-38 AZD7969 GDSC1 0.0391 10.0000
PCI-38 AZD8055 GDSC1 0.0078 2.0000
PCI-38 AZD8186 GDSC1 0.0098 2.5000
PCI-38 AZD8835 GDSC1 0.0391 10.0000
PCI-38 AZD8931 GDSC1 0.0391 10.0000
PCI-38 BAM7 GDSC1 0.0781 20.0000
PCI-38 BAY ACCi GDSC1 0.0391 10.0000
PCI-38 BAY AKT1 GDSC1 0.0391 10.0000
PCI-38 BAY-61-3606 GDSC1 0.0312 8.0000
PCI-38 BAY-HDAC11_1 GDSC1 0.0391 10.0000
PCI-38 BAY-HDAC11_2 GDSC1 0.0391 10.0000
PCI-38 BAY-HDAC11_4 GDSC1 0.0391 10.0000
PCI-38 BAY-MPS-combo 2 (paclitaxel 1 uM) GDSC1 0.0039 1.0000
PCI-38 BAY-MPS-combo-1 (paclitaxel 5 uM) GDSC1 0.0039 1.0000
PCI-38 BAY-MPS1 GDSC1 0.0117 3.0000
PCI-38 Belinostat GDSC1 0.0781 20.0000
PCI-38 Bexarotene GDSC1 0.0312 8.0000
PCI-38 BIBF-1120 GDSC1 0.0781 20.0000
PCI-38 Bicalutamide GDSC1 0.0040 10.0000
PCI-38 BIX02189 GDSC1 0.0781 20.0000
PCI-38 Bleomycin GDSC1 0.2500 64.0000
PCI-38 Bleomycin (10 uM) GDSC1 0.0391 10.0000
PCI-38 Bleomycin (50 uM) GDSC1 0.1953 50.0000
PCI-38 BMS-345541 GDSC1 0.0625 16.0000
PCI-38 BMS-536924 GDSC1 0.0156 4.0000
PCI-38 BMS-754807 GDSC1 0.0100 2.5600
PCI-38 Bosutinib GDSC1 0.0078 2.0000
PCI-38 BPTES GDSC1 0.0391 10.0000
PCI-38 Brivanib, BMS-540215 GDSC1 0.0781 20.0000
PCI-38 Bryostatin 1 GDSC1 0.0000 0.0080
PCI-38 BX-912 GDSC1 0.0400 10.2400
PCI-38 BX795 GDSC1 0.0195 5.0000
PCI-38 C-75 GDSC1 0.0781 20.0000
PCI-38 Cabozantinib GDSC1 0.0200 5.1200
PCI-38 CAP-232, TT-232, TLN-232 GDSC1 0.0781 20.0000
PCI-38 Capivasertib GDSC1 0.1172 30.0000
PCI-38 CAY10566 GDSC1 0.0100 2.5600
PCI-38 CAY10603 GDSC1 0.0781 20.0000
PCI-38 CCT-018159 GDSC1 0.0391 10.0000
PCI-38 CCT007093 GDSC1 0.0258 6.6000
PCI-38 CCT245232 GDSC1 0.0008 0.2000
PCI-38 CCT245467 GDSC1 0.0008 0.2000
PCI-38 CD532 GDSC1 0.0200 5.1200
PCI-38 Cetuximab GDSC1 0.2570 65.8000
PCI-38 CHIR-99021 GDSC1 0.0100 10.0000
PCI-38 CI-1033 GDSC1 0.0781 20.0000
PCI-38 CI-1040 GDSC1 0.0391 10.0000
PCI-38 Cisplatin GDSC1 0.0117 10.0000
PCI-38 CP466722 GDSC1 0.0625 16.0000
PCI-38 CP724714 GDSC1 0.0400 10.2400
PCI-38 CPI-613 GDSC1 1.0000 256.0000
PCI-38 CRT0105446 GDSC1 0.0391 10.0000
PCI-38 CRT0105950 GDSC1 0.0391 10.0000
PCI-38 CRT0160829 GDSC1 0.0781 20.0000
PCI-38 CUDC-101 GDSC1 0.0200 5.1200
PCI-38 CX-5461 GDSC1 0.0400 10.2400
PCI-38 Cytarabine GDSC1 0.0078 2.0000
PCI-38 Dabrafenib GDSC1 0.0391 10.0000
PCI-38 Dacinostat GDSC1 0.0040 1.0240
PCI-38 Dactolisib GDSC1 0.0010 0.2500
PCI-38 Daporinad GDSC1 0.0039 1.0000
PCI-38 DMOG GDSC1 15.6250 4000.0000
PCI-38 Docetaxel GDSC1 0.0000 0.0125
PCI-38 Doramapimod GDSC1 0.0391 10.0000
PCI-38 Doxorubicin GDSC1 0.0040 5.0000
PCI-38 Dyrk1b_0191 GDSC1 0.0391 10.0000
PCI-38 eEF2K Inhibitor, A-484954 GDSC1 0.0781 20.0000
PCI-38 EHT-1864 GDSC1 0.0391 10.0000
PCI-38 Elesclomol GDSC1 0.0008 0.2000
PCI-38 Embelin GDSC1 0.1250 32.0000
PCI-38 Enzastaurin GDSC1 0.0781 20.0000
PCI-38 EphB4_9721 GDSC1 0.0391 10.0000
PCI-38 Epothilone B GDSC1 0.0001 0.0320
PCI-38 Etoposide GDSC1 0.0625 16.0000
PCI-38 ETP-45835 GDSC1 0.0781 20.0000
PCI-38 Fedratinib GDSC1 0.0400 10.2400
PCI-38 FEN1_3940 GDSC1 0.0391 10.0000
PCI-38 FGFR_0939 GDSC1 0.0098 2.5000
PCI-38 FGFR_3831 GDSC1 0.0391 10.0000
PCI-38 FH535 GDSC1 0.1250 32.0000
PCI-38 Flavopiridol GDSC1 0.0100 2.5600
PCI-38 FMK GDSC1 0.0781 20.0000
PCI-38 Foretinib GDSC1 0.0200 5.1200
PCI-38 FR-180204 GDSC1 0.0781 20.0000
PCI-38 FS106 GDSC1 0.0391 10.0000
PCI-38 FS112 GDSC1 0.0195 5.0000
PCI-38 FTI-277 GDSC1 0.0040 1.0240
PCI-38 FTY-720 GDSC1 0.0781 20.0000
PCI-38 Fulvestrant GDSC1 0.0391 10.0000
PCI-38 FY012 GDSC1 0.0391 10.0000
PCI-38 FY026 GDSC1 0.0391 10.0000
PCI-38 FY069 GDSC1 0.0391 10.0000
PCI-38 Gefitinib GDSC1 0.0020 0.5000
PCI-38 Gemcitabine GDSC1 0.0002 1.0240
PCI-38 Genentech Cpd 10 GDSC1 0.0400 10.2400
PCI-38 GSK-J4 GDSC1 0.1172 30.0000
PCI-38 GSK1059615 GDSC1 0.0781 20.0000
PCI-38 GSK1070916 GDSC1 0.0100 2.5600
PCI-38 GSK1904529A GDSC1 0.0040 1.0240
PCI-38 GSK269962A GDSC1 0.0195 5.0000
PCI-38 GSK429286A GDSC1 0.0781 20.0000
PCI-38 GSK650394 GDSC1 0.0625 16.0000
PCI-38 GSK690693 GDSC1 0.0400 10.2400
PCI-38 GW-2580 GDSC1 0.0781 20.0000
PCI-38 GW441756 GDSC1 0.0078 2.0000
PCI-38 HG6-64-1 GDSC1 0.0200 5.1200
PCI-38 I-BET-762 GDSC1 0.0781 20.0000
PCI-38 I-BET151 GDSC1 0.0391 10.0000
PCI-38 I-CBP112 GDSC1 0.0391 10.0000
PCI-38 IAP_5620 GDSC1 0.0391 10.0000
PCI-38 IAP_7638 GDSC1 0.0391 10.0000
PCI-38 IC-87114 GDSC1 0.0781 20.0000
PCI-38 ICL1100013 GDSC1 0.0781 20.0000
PCI-38 Idelalisib GDSC1 0.0781 20.0000
PCI-38 IGFR_3801 GDSC1 0.0391 10.0000
PCI-38 IMD-0354 GDSC1 0.0781 20.0000
PCI-38 IOX2 GDSC1 0.0004 0.1000
PCI-38 IPA-3 GDSC1 0.1250 32.0000
PCI-38 Ispinesib Mesylate GDSC1 0.0005 0.1280
PCI-38 JAK1_3715 GDSC1 0.0391 10.0000
PCI-38 JAK3_7406 GDSC1 0.0391 10.0000
PCI-38 JNJ38877605 GDSC1 0.0781 20.0000
PCI-38 JNK Inhibitor VIII GDSC1 0.0391 10.0000
PCI-38 JNK-9L GDSC1 0.0200 5.1200
PCI-38 JQ1 GDSC1 0.0039 2.5600
PCI-38 JQ12 GDSC1 0.0200 5.1200
PCI-38 JW-7-24-1 GDSC1 0.0400 10.2400
PCI-38 kb NB 142-70 GDSC1 0.0781 20.0000
PCI-38 KIN001-042 GDSC1 0.0400 10.2400
PCI-38 KIN001-236 GDSC1 0.0400 10.2400
PCI-38 KIN001-244 GDSC1 0.0781 20.0000
PCI-38 KIN001-260 GDSC1 0.0781 20.0000
PCI-38 KIN001-266 GDSC1 0.0781 20.0000
PCI-38 KIN001-270 GDSC1 0.0781 20.0000
PCI-38 Kobe2602 GDSC1 0.0781 20.0000
PCI-38 KU-55933 GDSC1 0.0391 10.0000
PCI-38 KU-60019 GDSC1 0.0391 10.0000
PCI-38 LCL161 GDSC1 0.0100 2.5600
PCI-38 LDN-193189 GDSC1 0.0400 10.2400
PCI-38 Lenalidomide GDSC1 0.0195 5.0000
PCI-38 Lestaurtinib GDSC1 0.0078 2.0000
PCI-38 LFM-A13 GDSC1 0.0625 16.0000
PCI-38 LGK974 GDSC1 0.0100 2.5600
PCI-38 LIMK1 inhibitor BMS4 GDSC1 0.0781 20.0000
PCI-38 Linifanib GDSC1 0.0040 1.0240
PCI-38 Linsitinib GDSC1 0.0100 2.5600
PCI-38 Luminespib GDSC1 0.0010 0.2560
PCI-38 Masitinib GDSC1 0.0781 20.0000
PCI-38 MCT1_6447 GDSC1 0.0391 10.0000
PCI-38 MCT4_1422 GDSC1 0.0391 10.0000
PCI-38 MetAP2 Inhibitor, A832234 GDSC1 0.0100 2.5600
PCI-38 Methotrexate GDSC1 0.0008 0.2000
PCI-38 Midostaurin GDSC1 0.0020 0.5120
PCI-38 MIM1 GDSC1 0.1562 40.0000
PCI-38 Mirin GDSC1 0.3906 100.0000
PCI-38 Mitomycin-C GDSC1 0.0625 16.0000
PCI-38 MK-2206 GDSC1 0.0156 4.0000
PCI-38 Motesanib GDSC1 0.0078 2.0000
PCI-38 MPS-1-IN-1 GDSC1 0.0781 20.0000
PCI-38 N22899-6-C1 GDSC1 0.0391 10.0000
PCI-38 N23918-95-7 GDSC1 0.0391 10.0000
PCI-38 N24798-49-A1 GDSC1 0.0391 10.0000
PCI-38 Navitoclax GDSC1 0.0078 2.0000
PCI-38 NG-25 GDSC1 0.0400 10.2400
PCI-38 Nilotinib GDSC1 0.0078 2.0000
PCI-38 NPK76-II-72-1 GDSC1 0.0400 10.2400
PCI-38 NSC-207895 GDSC1 0.0781 20.0000
PCI-38 NSC-87877 GDSC1 0.0625 16.0000
PCI-38 NSC319726 GDSC1 0.0010 0.2560
PCI-38 NU7441 GDSC1 0.0078 2.0000
PCI-38 Nutlin-3a GDSC1 0.0312 8.0000
PCI-38 NVP-BHG712 GDSC1 0.0400 10.2400
PCI-38 Obatoclax Mesylate GDSC1 0.0625 16.0000
PCI-38 Olaparib GDSC1 0.0195 10.0000
PCI-38 Omipalisib GDSC1 0.0005 0.1280
PCI-38 OSI-027 GDSC1 0.0781 20.0000
PCI-38 OSI-930 GDSC1 0.0400 10.2400
PCI-38 OSU-03012 GDSC1 0.0625 16.0000
PCI-38 PAC-1 GDSC1 0.0100 2.5600
PCI-38 Palbociclib GDSC1 0.0156 4.0000
PCI-38 Panobinostat GDSC1 0.0040 1.0240
PCI-38 PARP_0108 GDSC1 0.0098 2.5000
PCI-38 PARP_9482 GDSC1 0.0098 2.5000
PCI-38 PARP_9495 GDSC1 0.0098 2.5000
PCI-38 Pazopanib GDSC1 0.0312 8.0000
PCI-38 PD0325901 GDSC1 0.0010 0.2500
PCI-38 PD173074 GDSC1 0.0078 2.0000
PCI-38 Pelitinib GDSC1 0.0098 2.5000
PCI-38 Pemetrexed GDSC1 0.0100 2.5600
PCI-38 Pevonedistat GDSC1 0.0039 1.0000
PCI-38 PF-00299804 GDSC1 0.0781 20.0000
PCI-38 PF-4708671 GDSC1 0.0391 10.0000
PCI-38 PF-562271 GDSC1 0.0100 2.5600
PCI-38 PFI-1 GDSC1 0.0391 10.0000
PCI-38 PFI3 GDSC1 0.0391 10.0000
PCI-38 PHA-793887 GDSC1 0.0400 10.2400
PCI-38 Phenformin GDSC1 15.6250 4000.0000
PCI-38 PI-103 GDSC1 0.0400 10.2400
PCI-38 PI3Ka_4409 GDSC1 0.0391 10.0000
PCI-38 Pictilisib GDSC1 0.0156 4.0000
PCI-38 PIK-93 GDSC1 0.0781 20.0000
PCI-38 Pilaralisib GDSC1 0.0781 20.0000
PCI-38 Piperlongumine GDSC1 0.0391 10.0000
PCI-38 PLK_6522 GDSC1 0.0024 0.6250
PCI-38 PLX-4720 GDSC1 0.0391 10.0000
PCI-38 Ponatinib GDSC1 0.0020 0.5120
PCI-38 QL-X-138 GDSC1 0.0400 10.2400
PCI-38 QL-XI-92 GDSC1 0.0400 10.2400
PCI-38 QL-XII-47 GDSC1 0.0400 10.2400
PCI-38 QS11 GDSC1 0.0400 10.2400
PCI-38 Quizartinib GDSC1 0.0040 1.0240
PCI-38 RAF_9304 GDSC1 0.0391 10.0000
PCI-38 Refametinib GDSC1 0.0195 5.0000
PCI-38 RO-3306 GDSC1 0.0195 5.0000
PCI-38 rTRAIL GDSC1 0.0004 0.1000
PCI-38 RU-SKI 43 GDSC1 0.0781 20.0000
PCI-38 Rucaparib GDSC1 0.0195 5.0000
PCI-38 Ruxolitinib GDSC1 0.0205 5.2400
PCI-38 SB216763 GDSC1 0.0391 10.0000
PCI-38 SB505124 GDSC1 0.0391 20.0000
PCI-38 SB52334 GDSC1 0.0781 20.0000
PCI-38 SB590885 GDSC1 0.0195 5.0000
PCI-38 Selisistat GDSC1 0.0781 20.0000
PCI-38 Selumetinib GDSC1 0.0156 4.0000
PCI-38 Sepantronium bromide GDSC1 0.0200 5.1200
PCI-38 Serdemetan GDSC1 0.0391 10.0000
PCI-38 SGC0946 GDSC1 0.0020 0.5000
PCI-38 Shikonin GDSC1 0.0625 16.0000
PCI-38 SL0101 GDSC1 0.0391 10.0000
PCI-38 SN-38 GDSC1 0.0002 0.1000
PCI-38 SNX-2112 GDSC1 0.0100 2.5600
PCI-38 Sphingosine Kinase 1 Inhibitor II GDSC1 0.0100 2.5600
PCI-38 STF-62247 GDSC1 0.0400 10.2400
PCI-38 SU11274 GDSC1 0.0400 10.2400
PCI-38 T0901317 GDSC1 0.0400 10.2400
PCI-38 TAK-715 GDSC1 0.0781 20.0000
PCI-38 Talazoparib GDSC1 0.0391 10.0000
PCI-38 Tamoxifen GDSC1 0.0195 5.0000
PCI-38 Tanespimycin GDSC1 0.0039 1.0000
PCI-38 TANK_1366 GDSC1 0.0098 2.5000
PCI-38 Temozolomide GDSC1 0.1172 30.0000
PCI-38 Temsirolimus GDSC1 0.0008 0.2000
PCI-38 Tenovin-6 GDSC1 0.0781 20.0000
PCI-38 Thapsigargin GDSC1 0.0020 0.5120
PCI-38 THZ-2-102-1 GDSC1 0.0098 2.5000
PCI-38 THZ-2-49 GDSC1 0.0781 20.0000
PCI-38 Tipifarnib GDSC1 0.0625 16.0000
PCI-38 Tivozanib GDSC1 0.0005 0.1280
PCI-38 TL-1-85 GDSC1 0.0400 10.2400
PCI-38 TL-2-105 GDSC1 0.0400 10.2400
PCI-38 Torin 2 GDSC1 0.0781 20.0000
PCI-38 TPCA-1 GDSC1 0.0781 20.0000
PCI-38 Trametinib GDSC1 0.0039 1.0000
PCI-38 Tretinoin GDSC1 0.0391 10.0000
PCI-38 Trichostatin A GDSC1 0.0040 1.0240
PCI-38 TTK_3146 GDSC1 0.0391 10.0000
PCI-38 Tubastatin A GDSC1 0.0781 20.0000
PCI-38 TW 37 GDSC1 0.0195 5.0000
PCI-38 TWS119 GDSC1 0.0781 20.0000
PCI-38 UNC0638 GDSC1 0.0781 40.0000
PCI-38 UNC0642 GDSC1 0.0020 0.5000
PCI-38 UNC1215 GDSC1 0.0039 1.0000
PCI-38 Veliparib GDSC1 0.0195 5.0000
PCI-38 Venotoclax GDSC1 0.0010 0.2560
PCI-38 Vinblastine GDSC1 0.0004 0.1000
PCI-38 Vinorelbine GDSC1 0.0003 0.0640
PCI-38 Vismodegib GDSC1 0.0391 10.0000
PCI-38 VNLG-124 GDSC1 0.0200 5.1200
PCI-38 Vorinostat GDSC1 0.0391 10.0000
PCI-38 Voxtalisib GDSC1 0.0781 20.0000
PCI-38 VX-11e GDSC1 0.0200 5.1200
PCI-38 VX-702 GDSC1 0.0078 2.0000
PCI-38 Wee1 Inhibitor GDSC1 0.0078 2.0000
PCI-38 WHI-P97 GDSC1 0.0400 10.2400
PCI-38 Wnt-C59 GDSC1 0.0100 2.5600
PCI-38 WYE-125132 GDSC1 0.0400 10.2400
PCI-38 WZ3105 GDSC1 0.0050 1.2800
PCI-38 XAV939 GDSC1 0.0195 5.0000
PCI-38 XMD13-2 GDSC1 0.0400 10.2400
PCI-38 XMD14-99 GDSC1 0.0400 10.2400
PCI-38 XMD15-27 GDSC1 0.0400 10.2400
PCI-38 Y-39983 GDSC1 0.0781 20.0000
PCI-38 YK-4-279 GDSC1 0.0391 10.0000
PCI-38 YM201636 GDSC1 0.0200 5.1200
PCI-38 Zibotentan GDSC1 0.0781 20.0000
PCI-38 ZL049 GDSC1 0.0391 10.0000
PCI-38 ZL109 GDSC1 0.0391 10.0000
PCI-38 ZM447439 GDSC1 0.0156 4.0000
PCI-38 ZSTK474 GDSC1 0.0200 5.1200

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Drugs with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Drugs with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Drugs with highest and lowest AUC