Cell Line : KP-N-RT-BM-1

Cellosaurus Index : CVCL_1339
Cellosaurus ID : KP-N-RT-BM-1

GDSC1 Name , GDSC2 Name : KP-N-RT-BM-1
CTRP2 Name : KPNRTBM1
CCLE Name : KPNRTBM1_AUTONOMIC_GANGLIA

Cancer Type : autonomic_ganglia
Dataset : All

Drug Response Information

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Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including cell line name, drug name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Cellosaurus ID Drug Name Original Dataset(s) Min Dose Max Dose Dose-response
KP-N-RT-BM-1 5-Fluorouracil GDSC2 0.0200 20.0000
KP-N-RT-BM-1 A-443654 GDSC1 0.0040 1.0240
KP-N-RT-BM-1 A-770041 GDSC1 0.0200 5.1200
KP-N-RT-BM-1 ABT737 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Afatinib GDSC2 0.0040 4.0000
KP-N-RT-BM-1 Afuresertib GDSC2 0.0100 10.0000
KP-N-RT-BM-1 AGI-5198 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 AGI-6780 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 AGK-2 GDSC2 0.0040 4.0000
KP-N-RT-BM-1 Alisertib GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Alpelisib GDSC2 0.0100 10.0000
KP-N-RT-BM-1 AMG-319 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 AT13148 GDSC2 0.0080 8.0000
KP-N-RT-BM-1 Avagacestat GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Axitinib GDSC2 0.0100 10.0000
KP-N-RT-BM-1 AZ6102 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 AZ960 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 AZD3759 GDSC2 0.0010 1.0000
KP-N-RT-BM-1 AZD4547 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 AZD5363 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 AZD5582 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 AZD6482 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 AZD6738 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 AZD7762 GDSC2 0.0010 2.0000
KP-N-RT-BM-1 AZD8186 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 BI-2536 GDSC1,GDSC2 0.0005 0.5000
KP-N-RT-BM-1 BIBR-1532 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Bicalutamide GDSC2 0.0100 10.0000
KP-N-RT-BM-1 BMS-345541 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 BMS-509744 GDSC1 0.0400 10.2400
KP-N-RT-BM-1 BMS-536924 GDSC1,GDSC2 0.0100 10.0000
KP-N-RT-BM-1 BMS-754807 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Bortezomib GDSC2 0.0000 0.0200
KP-N-RT-BM-1 Bosutinib GDSC2 0.0020 2.0000
KP-N-RT-BM-1 Buparlisib GDSC2 0.0100 10.0000
KP-N-RT-BM-1 BX795 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Camptothecin GDSC2 0.0001 0.1000
KP-N-RT-BM-1 CCT-018159 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 CCT007093 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Cediranib GDSC2 0.0100 10.0000
KP-N-RT-BM-1 CGP-082996 GDSC1 0.0200 5.1200
KP-N-RT-BM-1 CGP-60474 GDSC1 0.0010 0.2560
KP-N-RT-BM-1 CHIR-99021 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 CMK GDSC1 0.0156 4.0000
KP-N-RT-BM-1 Crizotinib GDSC1,GDSC2 0.0040 8.0000
KP-N-RT-BM-1 Cyclophosphamide GDSC2 0.0100 10.0000
KP-N-RT-BM-1 CZC24832 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Dabrafenib GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Dactinomycin GDSC2 0.0008 0.8000
KP-N-RT-BM-1 Dactolisib GDSC2 0.0003 0.2500
KP-N-RT-BM-1 Daporinad GDSC2 0.0010 1.0000
KP-N-RT-BM-1 Dasatinib GDSC1,GDSC2 0.0020 2.0000
KP-N-RT-BM-1 Dinaciclib GDSC2 0.0010 1.0000
KP-N-RT-BM-1 Docetaxel GDSC2 0.0000 0.0125
KP-N-RT-BM-1 Doramapimod GDSC2 0.0100 10.0000
KP-N-RT-BM-1 EHT-1864 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Elesclomol GDSC2 0.0002 0.2000
KP-N-RT-BM-1 Entinostat GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Entospletinib GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Epirubicin GDSC2 0.0100 10.0000
KP-N-RT-BM-1 EPZ004777 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 EPZ5676 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Erlotinib GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Foretinib GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Fulvestrant GDSC2 0.0010 1.0000
KP-N-RT-BM-1 GDC0810 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Gefitinib GDSC2 0.0020 2.0000
KP-N-RT-BM-1 Gemcitabine GDSC2 0.0100 10.0000
KP-N-RT-BM-1 GNE-317 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 GNF-2 GDSC1 0.0050 1.2800
KP-N-RT-BM-1 GSK1904529A GDSC2 0.0050 5.0000
KP-N-RT-BM-1 GSK2578215A GDSC2 0.0100 10.0000
KP-N-RT-BM-1 GSK2606414 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 GSK269962A GDSC2 0.0100 10.0000
KP-N-RT-BM-1 GSK343 GDSC2 0.0010 1.0000
KP-N-RT-BM-1 GSK591 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 GW441756 GDSC2 0.0020 2.0000
KP-N-RT-BM-1 GW843682X GDSC1 0.0010 0.2560
KP-N-RT-BM-1 I-BET-762 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 I-BRD9 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Ibrutinib GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Imatinib GDSC1 0.0078 2.0000
KP-N-RT-BM-1 IOX2 GDSC2 0.0005 0.5000
KP-N-RT-BM-1 Ipatasertib GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Irinotecan GDSC2 0.0050 5.0000
KP-N-RT-BM-1 IWP-2 GDSC2 0.0010 1.0000
KP-N-RT-BM-1 JNK Inhibitor VIII GDSC2 0.0100 10.0000
KP-N-RT-BM-1 JQ1 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 JW-7-52-1 GDSC1 0.0047 1.2000
KP-N-RT-BM-1 KRAS (G12C) Inhibitor-12 GDSC2 0.0200 20.0000
KP-N-RT-BM-1 KU-55933 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Lapatinib GDSC2 0.0100 10.0000
KP-N-RT-BM-1 LCL161 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Leflunomide GDSC2 0.1001 100.0000
KP-N-RT-BM-1 Lenalidomide GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Lestaurtinib GDSC2 0.0020 2.0000
KP-N-RT-BM-1 LGK974 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Linsitinib GDSC2 0.0100 10.0000
KP-N-RT-BM-1 LJI308 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Luminespib GDSC2 0.0003 0.2500
KP-N-RT-BM-1 LY2109761 GDSC2 0.0050 5.0000
KP-N-RT-BM-1 Methotrexate GDSC2 0.0010 1.0000
KP-N-RT-BM-1 MG-132 GDSC2 0.0040 4.0000
KP-N-RT-BM-1 MIRA-1 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Mirin GDSC2 0.1001 100.0000
KP-N-RT-BM-1 MK-1775 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 MK-2206 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 MK-8776 GDSC2 0.0050 5.0000
KP-N-RT-BM-1 ML323 GDSC2 0.0200 20.0000
KP-N-RT-BM-1 MN-64 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Motesanib GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Navitoclax GDSC2 0.0020 2.0000
KP-N-RT-BM-1 Nilotinib GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Niraparib GDSC2 0.0100 10.0000
KP-N-RT-BM-1 NU7441 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Nutlin-3a GDSC2 0.0100 10.0000
KP-N-RT-BM-1 NVP-ADW742 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 NVP-TAE684 GDSC1 0.0078 2.0000
KP-N-RT-BM-1 OF-1 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Olaparib GDSC2 0.0100 10.0000
KP-N-RT-BM-1 OSI-027 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Osimertinib GDSC2 0.0010 1.0000
KP-N-RT-BM-1 OTX015 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Oxaliplatin GDSC2 0.0100 10.0000
KP-N-RT-BM-1 P22077 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Paclitaxel GDSC1,GDSC2 0.0001 0.1024
KP-N-RT-BM-1 Palbociclib GDSC2 0.0040 4.0000
KP-N-RT-BM-1 PCI-34051 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 PD0325901 GDSC2 0.0025 2.5000
KP-N-RT-BM-1 PD173074 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Pevonedistat GDSC2 0.0100 10.0000
KP-N-RT-BM-1 PF-4708671 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 PFI-1 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 PFI3 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 PHA-665752 GDSC1 0.0078 2.0000
KP-N-RT-BM-1 Picolinici-acid GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Pictilisib GDSC2 0.0040 4.0000
KP-N-RT-BM-1 Piperlongumine GDSC2 0.0100 10.0000
KP-N-RT-BM-1 PLX-4720 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 PRIMA-1MET GDSC2 0.0300 30.0000
KP-N-RT-BM-1 PRT062607 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Pyridostatin GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Rapamycin GDSC1,GDSC2 0.0001 0.1000
KP-N-RT-BM-1 Refametinib GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Ribociclib GDSC2 0.0020 2.0000
KP-N-RT-BM-1 RO-3306 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Rucaparib GDSC2 0.0050 5.0000
KP-N-RT-BM-1 Ruxolitinib GDSC2 0.0100 10.0000
KP-N-RT-BM-1 RVX-208 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 S-Trityl-L-cysteine GDSC1 0.0200 5.1200
KP-N-RT-BM-1 Sabutoclax GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Sapitinib GDSC2 0.0050 5.0000
KP-N-RT-BM-1 Saracatinib GDSC1 0.0078 2.0000
KP-N-RT-BM-1 Savolitinib GDSC2 0.0010 1.0000
KP-N-RT-BM-1 SB216763 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 SB505124 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 SB590885 GDSC2 0.0050 5.0000
KP-N-RT-BM-1 SCH772984 GDSC2 0.0050 5.0000
KP-N-RT-BM-1 Selumetinib GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Sepantronium bromide GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Serdemetan GDSC2 0.0100 10.0000
KP-N-RT-BM-1 SGC0946 GDSC2 0.0005 0.5000
KP-N-RT-BM-1 SL0101 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 SN-38 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Sorafenib GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Staurosporine GDSC2 0.0078 2.0000
KP-N-RT-BM-1 Sunitinib GDSC1 0.0312 8.0000
KP-N-RT-BM-1 Talazoparib GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Tamoxifen GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Tanespimycin GDSC2 0.0010 1.0000
KP-N-RT-BM-1 Taselisib GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Telomerase Inhibitor IX GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Temozolomide GDSC2 0.0300 30.0000
KP-N-RT-BM-1 Temsirolimus GDSC2 0.0010 1.0000
KP-N-RT-BM-1 Tozasertib GDSC1,GDSC2 0.0050 5.0000
KP-N-RT-BM-1 Trametinib GDSC2 0.0010 1.0000
KP-N-RT-BM-1 Tretinoin GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Ulixertinib GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Uprosertib GDSC2 0.0100 10.0000
KP-N-RT-BM-1 VE-822 GDSC2 0.0050 5.0000
KP-N-RT-BM-1 VE821 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Veliparib GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Venetoclax GDSC2 0.0010 1.0000
KP-N-RT-BM-1 Vinorelbine GDSC2 0.0001 0.1000
KP-N-RT-BM-1 Vismodegib GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Vorinostat GDSC2 0.0100 10.0000
KP-N-RT-BM-1 VX-11e GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Wee1 Inhibitor GDSC2 0.0100 10.0000
KP-N-RT-BM-1 WEHI-539 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 WH-4-023 GDSC1 0.0200 5.1200
KP-N-RT-BM-1 WIKI4 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Wnt-C59 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 WZ-1-84 GDSC1 0.0400 10.2400
KP-N-RT-BM-1 WZ4003 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 XAV939 GDSC2 0.0050 5.0000
KP-N-RT-BM-1 YK-4-279 GDSC2 0.0100 10.0000
KP-N-RT-BM-1 Z-LLNle-CHO GDSC1 0.0100 2.5600
KP-N-RT-BM-1 ZM447439 GDSC2 0.0100 10.0000

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Drugs with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Drugs with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Drugs with highest and lowest AUC