Cell Line : D-245MG
Cellosaurus Index : CVCL_1152
Cellosaurus ID : D-245MG
GDSC2 Name
: D-245MG
CCLE Name
: D245MG_CENTRAL_NERVOUS_SYSTEM
Cancer Type : central_nervous_system
Dataset : All
Drug Response Information
Click to show/hide information cards below or download all drug response information.
Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.
Experimental information
Experimental information from All dataset, including cell line name, drug name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.
| Cellosaurus ID | Drug Name | Original Dataset(s) | Min Dose | Max Dose | Dose-response |
|---|---|---|---|---|---|
| D-245MG | 5-Fluorouracil | GDSC2 | 0.0200 | 20.0000 |
|
| D-245MG | ABT737 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Afatinib | GDSC2 | 0.0040 | 4.0000 |
|
| D-245MG | Afuresertib | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | AGI-5198 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | AGI-6780 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | AGK-2 | GDSC2 | 0.0040 | 4.0000 |
|
| D-245MG | Alisertib | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Alpelisib | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | AMG-319 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | AT13148 | GDSC2 | 0.0080 | 8.0000 |
|
| D-245MG | Avagacestat | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Axitinib | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | AZ6102 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | AZ960 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | AZD3759 | GDSC2 | 0.0010 | 1.0000 |
|
| D-245MG | AZD4547 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | AZD5363 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | AZD5582 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | AZD6482 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | AZD6738 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | AZD7762 | GDSC2 | 0.0010 | 2.0000 |
|
| D-245MG | AZD8186 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | BI-2536 | GDSC2 | 0.0005 | 0.5000 |
|
| D-245MG | BIBR-1532 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Bicalutamide | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | BMS-345541 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | BMS-536924 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | BMS-754807 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Bortezomib | GDSC2 | 0.0000 | 0.0200 |
|
| D-245MG | Bosutinib | GDSC2 | 0.0020 | 2.0000 |
|
| D-245MG | Buparlisib | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | BX795 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Camptothecin | GDSC2 | 0.0001 | 0.1000 |
|
| D-245MG | CCT-018159 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | CCT007093 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Cediranib | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | CHIR-99021 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Crizotinib | GDSC2 | 0.0040 | 8.0000 |
|
| D-245MG | Cyclophosphamide | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | CZC24832 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Dabrafenib | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Dactinomycin | GDSC2 | 0.0008 | 0.8000 |
|
| D-245MG | Dactolisib | GDSC2 | 0.0003 | 0.2500 |
|
| D-245MG | Daporinad | GDSC2 | 0.0010 | 1.0000 |
|
| D-245MG | Dasatinib | GDSC2 | 0.0020 | 2.0000 |
|
| D-245MG | Dinaciclib | GDSC2 | 0.0010 | 1.0000 |
|
| D-245MG | Docetaxel | GDSC2 | 0.0000 | 0.0125 |
|
| D-245MG | Doramapimod | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | EHT-1864 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Elesclomol | GDSC2 | 0.0002 | 0.2000 |
|
| D-245MG | Entinostat | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Entospletinib | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Epirubicin | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | EPZ004777 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | EPZ5676 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Erlotinib | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Foretinib | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Fulvestrant | GDSC2 | 0.0010 | 1.0000 |
|
| D-245MG | GDC0810 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Gefitinib | GDSC2 | 0.0020 | 2.0000 |
|
| D-245MG | Gemcitabine | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | GNE-317 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | GSK1904529A | GDSC2 | 0.0050 | 5.0000 |
|
| D-245MG | GSK2578215A | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | GSK2606414 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | GSK269962A | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | GSK343 | GDSC2 | 0.0010 | 1.0000 |
|
| D-245MG | GSK591 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | GW441756 | GDSC2 | 0.0020 | 2.0000 |
|
| D-245MG | I-BET-762 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | I-BRD9 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Ibrutinib | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | IOX2 | GDSC2 | 0.0005 | 0.5000 |
|
| D-245MG | Ipatasertib | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Irinotecan | GDSC2 | 0.0050 | 5.0000 |
|
| D-245MG | IWP-2 | GDSC2 | 0.0010 | 1.0000 |
|
| D-245MG | JNK Inhibitor VIII | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | JQ1 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | KRAS (G12C) Inhibitor-12 | GDSC2 | 0.0200 | 20.0000 |
|
| D-245MG | KU-55933 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Lapatinib | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | LCL161 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Leflunomide | GDSC2 | 0.1001 | 100.0000 |
|
| D-245MG | Lenalidomide | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Lestaurtinib | GDSC2 | 0.0020 | 2.0000 |
|
| D-245MG | LGK974 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Linsitinib | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | LJI308 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Luminespib | GDSC2 | 0.0003 | 0.2500 |
|
| D-245MG | LY2109761 | GDSC2 | 0.0050 | 5.0000 |
|
| D-245MG | Methotrexate | GDSC2 | 0.0010 | 1.0000 |
|
| D-245MG | MG-132 | GDSC2 | 0.0040 | 4.0000 |
|
| D-245MG | MIRA-1 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Mirin | GDSC2 | 0.1001 | 100.0000 |
|
| D-245MG | MK-1775 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | MK-2206 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | MK-8776 | GDSC2 | 0.0050 | 5.0000 |
|
| D-245MG | ML323 | GDSC2 | 0.0200 | 20.0000 |
|
| D-245MG | MN-64 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Motesanib | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Navitoclax | GDSC2 | 0.0020 | 2.0000 |
|
| D-245MG | Nilotinib | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Niraparib | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | NU7441 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Nutlin-3a | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | NVP-ADW742 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | OF-1 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Olaparib | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | OSI-027 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Osimertinib | GDSC2 | 0.0010 | 1.0000 |
|
| D-245MG | OTX015 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Oxaliplatin | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | P22077 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Paclitaxel | GDSC2 | 0.0001 | 0.1000 |
|
| D-245MG | Palbociclib | GDSC2 | 0.0040 | 4.0000 |
|
| D-245MG | PCI-34051 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | PD0325901 | GDSC2 | 0.0025 | 2.5000 |
|
| D-245MG | PD173074 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Pevonedistat | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | PF-4708671 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | PFI-1 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | PFI3 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Picolinici-acid | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Pictilisib | GDSC2 | 0.0040 | 4.0000 |
|
| D-245MG | Piperlongumine | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | PLX-4720 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | PRIMA-1MET | GDSC2 | 0.0300 | 30.0000 |
|
| D-245MG | PRT062607 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Pyridostatin | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Rapamycin | GDSC2 | 0.0001 | 0.1000 |
|
| D-245MG | Refametinib | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Ribociclib | GDSC2 | 0.0020 | 2.0000 |
|
| D-245MG | RO-3306 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Rucaparib | GDSC2 | 0.0050 | 5.0000 |
|
| D-245MG | Ruxolitinib | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | RVX-208 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Sabutoclax | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Sapitinib | GDSC2 | 0.0050 | 5.0000 |
|
| D-245MG | Savolitinib | GDSC2 | 0.0010 | 1.0000 |
|
| D-245MG | SB216763 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | SB505124 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | SB590885 | GDSC2 | 0.0050 | 5.0000 |
|
| D-245MG | SCH772984 | GDSC2 | 0.0050 | 5.0000 |
|
| D-245MG | Selumetinib | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Sepantronium bromide | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Serdemetan | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | SGC0946 | GDSC2 | 0.0005 | 0.5000 |
|
| D-245MG | SL0101 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | SN-38 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Sorafenib | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Staurosporine | GDSC2 | 0.0078 | 2.0000 |
|
| D-245MG | Talazoparib | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Tamoxifen | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Tanespimycin | GDSC2 | 0.0010 | 1.0000 |
|
| D-245MG | Taselisib | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Telomerase Inhibitor IX | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Temozolomide | GDSC2 | 0.0300 | 30.0000 |
|
| D-245MG | Temsirolimus | GDSC2 | 0.0010 | 1.0000 |
|
| D-245MG | Tozasertib | GDSC2 | 0.0050 | 5.0000 |
|
| D-245MG | Trametinib | GDSC2 | 0.0010 | 1.0000 |
|
| D-245MG | Tretinoin | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Ulixertinib | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Uprosertib | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | VE-822 | GDSC2 | 0.0050 | 5.0000 |
|
| D-245MG | VE821 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Veliparib | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Venetoclax | GDSC2 | 0.0010 | 1.0000 |
|
| D-245MG | Vinorelbine | GDSC2 | 0.0001 | 0.1000 |
|
| D-245MG | Vismodegib | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Vorinostat | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | VX-11e | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Wee1 Inhibitor | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | WEHI-539 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | WIKI4 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | Wnt-C59 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | WZ4003 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | XAV939 | GDSC2 | 0.0050 | 5.0000 |
|
| D-245MG | YK-4-279 | GDSC2 | 0.0100 | 10.0000 |
|
| D-245MG | ZM447439 | GDSC2 | 0.0100 | 10.0000 |
|
IC50
IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.
Drugs with highest and lowest IC50
Drugs with highest and lowest IC50
IC90
IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.
Drugs with highest and lowest IC90
Drugs with highest and lowest IC90
AUC
AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.
Drugs with highest and lowest AUC
Drugs with highest and lowest AUC