Cell Line : BONNA-12

Cellosaurus Index : CVCL_1090
Cellosaurus ID : BONNA-12

GDSC2 Name : BONNA-12
CCLE Name : BONNA12_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE

Cancer Type : haematopoietic_and_lymphoid_tissue
Dataset : All

Drug Response Information

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Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including cell line name, drug name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Cellosaurus ID Drug Name Original Dataset(s) Min Dose Max Dose Dose-response
BONNA-12 5-Fluorouracil GDSC2 0.0200 20.0000
BONNA-12 ABT737 GDSC2 0.0100 10.0000
BONNA-12 Afatinib GDSC2 0.0040 4.0000
BONNA-12 Afuresertib GDSC2 0.0100 10.0000
BONNA-12 AGI-5198 GDSC2 0.0100 10.0000
BONNA-12 AGI-6780 GDSC2 0.0100 10.0000
BONNA-12 AGK-2 GDSC2 0.0040 4.0000
BONNA-12 Alisertib GDSC2 0.0100 10.0000
BONNA-12 Alpelisib GDSC2 0.0100 10.0000
BONNA-12 AMG-319 GDSC2 0.0100 10.0000
BONNA-12 AT13148 GDSC2 0.0080 8.0000
BONNA-12 Avagacestat GDSC2 0.0100 10.0000
BONNA-12 Axitinib GDSC2 0.0100 10.0000
BONNA-12 AZ6102 GDSC2 0.0100 10.0000
BONNA-12 AZ960 GDSC2 0.0100 10.0000
BONNA-12 AZD3759 GDSC2 0.0010 1.0000
BONNA-12 AZD4547 GDSC2 0.0100 10.0000
BONNA-12 AZD5363 GDSC2 0.0100 10.0000
BONNA-12 AZD5582 GDSC2 0.0100 10.0000
BONNA-12 AZD6482 GDSC2 0.0100 10.0000
BONNA-12 AZD6738 GDSC2 0.0100 10.0000
BONNA-12 AZD7762 GDSC2 0.0010 2.0000
BONNA-12 AZD8186 GDSC2 0.0100 10.0000
BONNA-12 BI-2536 GDSC2 0.0005 0.5000
BONNA-12 BIBR-1532 GDSC2 0.0100 10.0000
BONNA-12 Bicalutamide GDSC2 0.0100 10.0000
BONNA-12 BMS-345541 GDSC2 0.0100 10.0000
BONNA-12 BMS-536924 GDSC2 0.0100 10.0000
BONNA-12 BMS-754807 GDSC2 0.0100 10.0000
BONNA-12 Bortezomib GDSC2 0.0000 0.0200
BONNA-12 Bosutinib GDSC2 0.0020 2.0000
BONNA-12 Buparlisib GDSC2 0.0100 10.0000
BONNA-12 BX795 GDSC2 0.0100 10.0000
BONNA-12 Camptothecin GDSC2 0.0001 0.1000
BONNA-12 CCT-018159 GDSC2 0.0100 10.0000
BONNA-12 CCT007093 GDSC2 0.0100 10.0000
BONNA-12 Cediranib GDSC2 0.0100 10.0000
BONNA-12 CHIR-99021 GDSC2 0.0100 10.0000
BONNA-12 Crizotinib GDSC2 0.0040 8.0000
BONNA-12 Cyclophosphamide GDSC2 0.0100 10.0000
BONNA-12 CZC24832 GDSC2 0.0100 10.0000
BONNA-12 Dabrafenib GDSC2 0.0100 10.0000
BONNA-12 Dactinomycin GDSC2 0.0008 0.8000
BONNA-12 Dactolisib GDSC2 0.0003 0.2500
BONNA-12 Daporinad GDSC2 0.0010 1.0000
BONNA-12 Dasatinib GDSC2 0.0020 2.0000
BONNA-12 Dinaciclib GDSC2 0.0010 1.0000
BONNA-12 Docetaxel GDSC2 0.0000 0.0125
BONNA-12 Doramapimod GDSC2 0.0100 10.0000
BONNA-12 EHT-1864 GDSC2 0.0100 10.0000
BONNA-12 Elesclomol GDSC2 0.0002 0.2000
BONNA-12 Entinostat GDSC2 0.0100 10.0000
BONNA-12 Entospletinib GDSC2 0.0100 10.0000
BONNA-12 Epirubicin GDSC2 0.0100 10.0000
BONNA-12 EPZ004777 GDSC2 0.0100 10.0000
BONNA-12 EPZ5676 GDSC2 0.0100 10.0000
BONNA-12 Erlotinib GDSC2 0.0100 10.0000
BONNA-12 Foretinib GDSC2 0.0100 10.0000
BONNA-12 Fulvestrant GDSC2 0.0010 1.0000
BONNA-12 GDC0810 GDSC2 0.0100 10.0000
BONNA-12 Gefitinib GDSC2 0.0020 2.0000
BONNA-12 Gemcitabine GDSC2 0.0100 10.0000
BONNA-12 GNE-317 GDSC2 0.0100 10.0000
BONNA-12 GSK1904529A GDSC2 0.0050 5.0000
BONNA-12 GSK2578215A GDSC2 0.0100 10.0000
BONNA-12 GSK2606414 GDSC2 0.0100 10.0000
BONNA-12 GSK269962A GDSC2 0.0100 10.0000
BONNA-12 GSK343 GDSC2 0.0010 1.0000
BONNA-12 GSK591 GDSC2 0.0100 10.0000
BONNA-12 GW441756 GDSC2 0.0020 2.0000
BONNA-12 I-BET-762 GDSC2 0.0100 10.0000
BONNA-12 I-BRD9 GDSC2 0.0100 10.0000
BONNA-12 Ibrutinib GDSC2 0.0100 10.0000
BONNA-12 IOX2 GDSC2 0.0005 0.5000
BONNA-12 Ipatasertib GDSC2 0.0100 10.0000
BONNA-12 Irinotecan GDSC2 0.0050 5.0000
BONNA-12 IWP-2 GDSC2 0.0010 1.0000
BONNA-12 JNK Inhibitor VIII GDSC2 0.0100 10.0000
BONNA-12 JQ1 GDSC2 0.0100 10.0000
BONNA-12 KRAS (G12C) Inhibitor-12 GDSC2 0.0200 20.0000
BONNA-12 KU-55933 GDSC2 0.0100 10.0000
BONNA-12 Lapatinib GDSC2 0.0100 10.0000
BONNA-12 LCL161 GDSC2 0.0100 10.0000
BONNA-12 Leflunomide GDSC2 0.1001 100.0000
BONNA-12 Lenalidomide GDSC2 0.0100 10.0000
BONNA-12 Lestaurtinib GDSC2 0.0020 2.0000
BONNA-12 LGK974 GDSC2 0.0100 10.0000
BONNA-12 Linsitinib GDSC2 0.0100 10.0000
BONNA-12 LJI308 GDSC2 0.0100 10.0000
BONNA-12 Luminespib GDSC2 0.0003 0.2500
BONNA-12 LY2109761 GDSC2 0.0050 5.0000
BONNA-12 Methotrexate GDSC2 0.0010 1.0000
BONNA-12 MG-132 GDSC2 0.0040 4.0000
BONNA-12 MIRA-1 GDSC2 0.0100 10.0000
BONNA-12 Mirin GDSC2 0.1001 100.0000
BONNA-12 MK-1775 GDSC2 0.0100 10.0000
BONNA-12 MK-2206 GDSC2 0.0100 10.0000
BONNA-12 MK-8776 GDSC2 0.0050 5.0000
BONNA-12 ML323 GDSC2 0.0200 20.0000
BONNA-12 MN-64 GDSC2 0.0100 10.0000
BONNA-12 Motesanib GDSC2 0.0100 10.0000
BONNA-12 Navitoclax GDSC2 0.0020 2.0000
BONNA-12 Nilotinib GDSC2 0.0100 10.0000
BONNA-12 Niraparib GDSC2 0.0100 10.0000
BONNA-12 NU7441 GDSC2 0.0100 10.0000
BONNA-12 Nutlin-3a GDSC2 0.0100 10.0000
BONNA-12 NVP-ADW742 GDSC2 0.0100 10.0000
BONNA-12 OF-1 GDSC2 0.0100 10.0000
BONNA-12 Olaparib GDSC2 0.0100 10.0000
BONNA-12 OSI-027 GDSC2 0.0100 10.0000
BONNA-12 Osimertinib GDSC2 0.0010 1.0000
BONNA-12 OTX015 GDSC2 0.0100 10.0000
BONNA-12 Oxaliplatin GDSC2 0.0100 10.0000
BONNA-12 P22077 GDSC2 0.0100 10.0000
BONNA-12 Paclitaxel GDSC2 0.0001 0.1000
BONNA-12 Palbociclib GDSC2 0.0040 4.0000
BONNA-12 PCI-34051 GDSC2 0.0100 10.0000
BONNA-12 PD0325901 GDSC2 0.0025 2.5000
BONNA-12 PD173074 GDSC2 0.0100 10.0000
BONNA-12 Pevonedistat GDSC2 0.0100 10.0000
BONNA-12 PF-4708671 GDSC2 0.0100 10.0000
BONNA-12 PFI-1 GDSC2 0.0100 10.0000
BONNA-12 PFI3 GDSC2 0.0100 10.0000
BONNA-12 Picolinici-acid GDSC2 0.0100 10.0000
BONNA-12 Pictilisib GDSC2 0.0040 4.0000
BONNA-12 Piperlongumine GDSC2 0.0100 10.0000
BONNA-12 PLX-4720 GDSC2 0.0100 10.0000
BONNA-12 PRIMA-1MET GDSC2 0.0300 30.0000
BONNA-12 PRT062607 GDSC2 0.0100 10.0000
BONNA-12 Pyridostatin GDSC2 0.0100 10.0000
BONNA-12 Rapamycin GDSC2 0.0001 0.1000
BONNA-12 Refametinib GDSC2 0.0100 10.0000
BONNA-12 Ribociclib GDSC2 0.0020 2.0000
BONNA-12 RO-3306 GDSC2 0.0100 10.0000
BONNA-12 Rucaparib GDSC2 0.0050 5.0000
BONNA-12 Ruxolitinib GDSC2 0.0100 10.0000
BONNA-12 RVX-208 GDSC2 0.0100 10.0000
BONNA-12 Sabutoclax GDSC2 0.0100 10.0000
BONNA-12 Sapitinib GDSC2 0.0050 5.0000
BONNA-12 Savolitinib GDSC2 0.0010 1.0000
BONNA-12 SB216763 GDSC2 0.0100 10.0000
BONNA-12 SB505124 GDSC2 0.0100 10.0000
BONNA-12 SB590885 GDSC2 0.0050 5.0000
BONNA-12 SCH772984 GDSC2 0.0050 5.0000
BONNA-12 Selumetinib GDSC2 0.0100 10.0000
BONNA-12 Sepantronium bromide GDSC2 0.0100 10.0000
BONNA-12 Serdemetan GDSC2 0.0100 10.0000
BONNA-12 SGC0946 GDSC2 0.0005 0.5000
BONNA-12 SL0101 GDSC2 0.0100 10.0000
BONNA-12 SN-38 GDSC2 0.0100 10.0000
BONNA-12 Sorafenib GDSC2 0.0100 10.0000
BONNA-12 Staurosporine GDSC2 0.0078 2.0000
BONNA-12 Talazoparib GDSC2 0.0100 10.0000
BONNA-12 Tamoxifen GDSC2 0.0100 10.0000
BONNA-12 Tanespimycin GDSC2 0.0010 1.0000
BONNA-12 Taselisib GDSC2 0.0100 10.0000
BONNA-12 Telomerase Inhibitor IX GDSC2 0.0100 10.0000
BONNA-12 Temozolomide GDSC2 0.0300 30.0000
BONNA-12 Temsirolimus GDSC2 0.0010 1.0000
BONNA-12 Tozasertib GDSC2 0.0050 5.0000
BONNA-12 Trametinib GDSC2 0.0010 1.0000
BONNA-12 Tretinoin GDSC2 0.0100 10.0000
BONNA-12 Ulixertinib GDSC2 0.0100 10.0000
BONNA-12 Uprosertib GDSC2 0.0100 10.0000
BONNA-12 VE-822 GDSC2 0.0050 5.0000
BONNA-12 VE821 GDSC2 0.0100 10.0000
BONNA-12 Veliparib GDSC2 0.0100 10.0000
BONNA-12 Venetoclax GDSC2 0.0010 1.0000
BONNA-12 Vinorelbine GDSC2 0.0001 0.1000
BONNA-12 Vismodegib GDSC2 0.0100 10.0000
BONNA-12 Vorinostat GDSC2 0.0100 10.0000
BONNA-12 VX-11e GDSC2 0.0100 10.0000
BONNA-12 Wee1 Inhibitor GDSC2 0.0100 10.0000
BONNA-12 WEHI-539 GDSC2 0.0100 10.0000
BONNA-12 WIKI4 GDSC2 0.0100 10.0000
BONNA-12 Wnt-C59 GDSC2 0.0100 10.0000
BONNA-12 WZ4003 GDSC2 0.0100 10.0000
BONNA-12 XAV939 GDSC2 0.0050 5.0000
BONNA-12 YK-4-279 GDSC2 0.0100 10.0000
BONNA-12 ZM447439 GDSC2 0.0100 10.0000

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Drugs with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Drugs with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Drugs with highest and lowest AUC