Cell Line : LC-1F

Cellosaurus Index : CVCL_1372
Cellosaurus ID : LC-1F

CCLE Name : LC1F_LUNG
CTRP2 Name : LC1F

Cancer Type : lung
Dataset : All

Drug Response Information

Click to show/hide information cards below or download all drug response information.

           

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including cell line name, drug name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Cellosaurus ID Drug Name Original Dataset(s) Min Dose Max Dose Dose-response
LC-1F Afatinib CTRP2 0.0020 66.0000
LC-1F alisertib:navitoclax (2:1 mol-mol) CTRP2 0.0015 50.0000
LC-1F AM-580 CTRP2 0.0160 530.0000
LC-1F AT7867 CTRP2 0.0020 66.0000
LC-1F Axitinib CTRP2 0.0020 66.0000
LC-1F AZD4547 CTRP2 0.0020 0.2600
LC-1F B02 CTRP2 0.0041 130.0000
LC-1F BRD-A71883111 CTRP2 0.0010 0.1300
LC-1F BRD-K42260513 CTRP2 0.0020 66.0000
LC-1F BRD-K50799972 CTRP2 0.0020 17.0000
LC-1F BRD-K71781559 CTRP2 0.0020 66.0000
LC-1F BRD-K80183349 CTRP2 0.0020 0.2600
LC-1F BRD9876 CTRP2 0.0041 130.0000
LC-1F C6-ceramide CTRP2 0.0020 0.2600
LC-1F ceranib-2 CTRP2 0.0020 66.0000
LC-1F CI-976 CTRP2 0.0081 1.0000
LC-1F curcumin CTRP2 0.0051 170.0000
LC-1F erastin CTRP2 0.0020 66.0000
LC-1F fluorouracil CTRP2 0.0041 130.0000
LC-1F GDC-0879 CTRP2 0.0020 66.0000
LC-1F Gefitinib CTRP2 0.0020 66.0000
LC-1F GSK-3 inhibitor IX CTRP2 0.0020 0.2600
LC-1F GSK4112 CTRP2 0.0020 0.2600
LC-1F GSK461364 CTRP2 0.0020 66.0000
LC-1F GW-405833 CTRP2 0.0041 0.5200
LC-1F HBX-41108 CTRP2 0.0020 0.2600
LC-1F HC-067047 CTRP2 0.0020 0.2600
LC-1F IC-87114 CTRP2 0.0020 66.0000
LC-1F Imatinib CTRP2 0.0020 66.0000
LC-1F JQ-1:MK-0752 (1:1 mol-mol) CTRP2 0.0020 66.0000
LC-1F JW-480 CTRP2 0.0020 66.0000
LC-1F Ko-143 CTRP2 0.0041 0.5200
LC-1F KU 0060648 CTRP2 0.0010 33.0000
LC-1F KW-2449 CTRP2 0.0020 0.2600
LC-1F KX2-391 CTRP2 0.0020 66.0000
LC-1F Lapatinib CTRP2 0.0020 0.2600
LC-1F LBH-589 CTRP2 0.0020 66.0000
LC-1F Lenvatinib CTRP2 0.0020 66.0000
LC-1F Linifanib CTRP2 0.0020 66.0000
LC-1F lovastatin acid CTRP2 0.0041 0.5200
LC-1F LY-2183240 CTRP2 0.0010 33.0000
LC-1F MI-1 CTRP2 0.0010 0.1300
LC-1F narciclasine CTRP2 0.0010 33.0000
LC-1F Navitoclax CTRP2 0.0010 33.0000
LC-1F niclosamide CTRP2 0.0010 33.0000
LC-1F nintedanib CTRP2 0.0020 0.2600
LC-1F NSC30930 CTRP2 0.0020 66.0000
LC-1F NSC48300 CTRP2 0.0020 66.0000
LC-1F NVP-TAE684 CTRP2 0.0020 66.0000
LC-1F parbendazole CTRP2 0.0020 66.0000
LC-1F Parthenolide CTRP2 0.0020 0.2600
LC-1F Pazopanib CTRP2 0.0020 66.0000
LC-1F PD318088 CTRP2 0.0020 66.0000
LC-1F PHA-793887 CTRP2 0.0020 66.0000
LC-1F phloretin CTRP2 0.0180 590.0000
LC-1F Platin CTRP2 0.0020 0.2600
LC-1F prochlorperazine CTRP2 0.0020 66.0000
LC-1F purmorphamine CTRP2 0.0046 150.0000
LC-1F PYR-41 CTRP2 0.0020 0.2600
LC-1F Regorafenib CTRP2 0.0020 0.2600
LC-1F RITA CTRP2 0.0010 0.1300
LC-1F SB-743921 CTRP2 0.0010 0.1300
LC-1F SCH-79797 CTRP2 0.0011 37.0000
LC-1F Selumetinib CTRP2 0.0081 270.0000
LC-1F selumetinib:JQ-1 (4:1 mol-mol) CTRP2 0.0051 170.0000
LC-1F selumetinib:piperlongumine (8:1 mol-mol) CTRP2 0.0046 150.0000
LC-1F selumetinib:tretinoin (2:1 mol-mol) CTRP2 0.0061 200.0000
LC-1F selumetinib:vorinostat (8:1 mol-mol) CTRP2 0.0046 150.0000
LC-1F SGX-523 CTRP2 0.0020 66.0000
LC-1F simvastatin CTRP2 0.0010 0.1300
LC-1F sirolimus:bortezomib (250:1 mol-mol) CTRP2 0.0005 17.0000
LC-1F SNX-2112:bortezomib (250:1 mol-mol) CTRP2 0.0005 17.0000
LC-1F Sorafenib CTRP2 0.0020 66.0000
LC-1F StemRegenin 1 CTRP2 0.0020 0.2600
LC-1F tanespimycin:bortezomib (250:1 mol-mol) CTRP2 0.0005 17.0000
LC-1F Temozolomide CTRP2 0.0020 0.2600
LC-1F TPCA-1 CTRP2 0.0020 66.0000
LC-1F Tretinoin CTRP2 0.0041 0.5200
LC-1F tretinoin:carboplatin (2:1 mol-mol) CTRP2 0.0030 100.0000
LC-1F trifluoperazine CTRP2 0.0010 33.0000
LC-1F UNC0321 CTRP2 0.0010 0.1300
LC-1F vorinostat:carboplatin (1:1 mol-mol) CTRP2 0.0020 66.0000

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Drugs with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Drugs with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Drugs with highest and lowest AUC