Drug : Oxythiamine

CTRP1 Name : oxythiamine

Dataset : All
Synonyms :
Targets : TKT
Pathways : inhibitor of transketolase;inhibitor of pentose phosphate pathway

Information Cards

Click to show/hide information cards below or download all drug response information.

           
     

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including drug name, cell line name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Drug name Cellosaurus ID Original Dataset(s) Min Dose Max Dose Dose-response
oxythiamine GAMG CTRP1 0.2603 33.3330
oxythiamine SF295 CTRP1 0.2603 33.3330
oxythiamine HEC-108 CTRP1 0.2603 33.3330
oxythiamine HEC-251 CTRP1 0.2603 33.3330
oxythiamine HEC-265 CTRP1 0.2603 33.3330
oxythiamine HEC-59 CTRP1 0.2603 33.3330
oxythiamine HEC-6 CTRP1 0.2603 33.3330
oxythiamine ISHIKAWA(HERAKLIO)02ER- CTRP1 0.2603 33.3330
oxythiamine KLE CTRP1 0.2603 33.3330
oxythiamine MFE-319 CTRP1 0.2603 33.3330
oxythiamine SNG-M CTRP1 0.2603 33.3330
oxythiamine BL-70 CTRP1 0.2603 33.3330
oxythiamine HT CTRP1 0.2603 33.3330
oxythiamine KU812 CTRP1 0.2603 33.3330
oxythiamine MC116 CTRP1 0.2603 33.3330
oxythiamine P3HR-1 CTRP1 0.2603 33.3330
oxythiamine VMRC-RCW CTRP1 0.2603 33.3330
oxythiamine SNU-C2A CTRP1 0.2603 33.3330
oxythiamine SW403 CTRP1 0.2603 33.3330
oxythiamine JHH-6 CTRP1 0.2603 33.3330
oxythiamine SNU-449 CTRP1 0.2603 33.3330
oxythiamine A-549 CTRP1 0.2603 33.3330
oxythiamine BEN CTRP1 0.2603 33.3330
oxythiamine CALU-3 CTRP1 0.2603 33.3330
oxythiamine CALU-6 CTRP1 0.2603 33.3330
oxythiamine CHAGO-K-1 CTRP1 0.2603 33.3330
oxythiamine COLO668 CTRP1 0.2603 33.3330
oxythiamine COR-L279 CTRP1 0.2603 33.3330
oxythiamine COR-L88 CTRP1 0.2603 33.3330
oxythiamine DMS273 CTRP1 0.2603 33.3330
oxythiamine DV-90 CTRP1 0.2603 33.3330
oxythiamine EPLC-272H CTRP1 0.2603 33.3330
oxythiamine HARA[HUMANSQUAMOUSCELLLUNGCARCINOMA] CTRP1 0.2603 33.3330
oxythiamine HCC33 CTRP1 0.2603 33.3330
oxythiamine HCC44 CTRP1 0.2603 33.3330
oxythiamine KNS-62 CTRP1 0.2603 33.3330
oxythiamine LC-1-SQ-SF CTRP1 0.2603 33.3330
oxythiamine LCLC-103H CTRP1 0.2603 33.3330
oxythiamine LCLC-97TM1 CTRP1 0.2603 33.3330
oxythiamine LU-65 CTRP1 0.2603 33.3330
oxythiamine LXF289 CTRP1 0.2603 33.3330
oxythiamine NCI-H1048 CTRP1 0.2603 33.3330
oxythiamine NCI-H1299 CTRP1 0.2603 33.3330
oxythiamine NCI-H1355 CTRP1 0.2603 33.3330
oxythiamine NCI-H1435 CTRP1 0.2603 33.3330
oxythiamine NCI-H1437 CTRP1 0.2603 33.3330
oxythiamine NCI-H1568 CTRP1 0.2603 33.3330
oxythiamine NCI-H1573 CTRP1 0.2603 33.3330
oxythiamine NCI-H1666 CTRP1 0.2603 33.3330
oxythiamine NCI-H1792 CTRP1 0.2603 33.3330
oxythiamine NCI-H1915 CTRP1 0.2603 33.3330
oxythiamine NCI-H1930 CTRP1 0.2603 33.3330
oxythiamine NCI-H1944 CTRP1 0.2603 33.3330
oxythiamine NCI-H1975 CTRP1 0.2603 33.3330
oxythiamine NCI-H2009 CTRP1 0.2603 33.3330
oxythiamine NCI-H2029 CTRP1 0.2603 33.3330
oxythiamine NCI-H2126 CTRP1 0.2603 33.3330
oxythiamine NCI-H2286 CTRP1 0.2603 33.3330
oxythiamine NCI-H23 CTRP1 0.2603 33.3330
oxythiamine NCI-H2405 CTRP1 0.2603 33.3330
oxythiamine NCI-H650 CTRP1 0.2603 33.3330
oxythiamine NCI-H661 CTRP1 0.2603 33.3330
oxythiamine NCI-H727 CTRP1 0.2603 33.3330
oxythiamine NCI-H810 CTRP1 0.2603 33.3330
oxythiamine NCI-H82 CTRP1 0.2603 33.3330
oxythiamine RERF-LC-KJ CTRP1 0.2603 33.3330
oxythiamine SHP-77 CTRP1 0.2603 33.3330
oxythiamine VMRC-LCD CTRP1 0.2603 33.3330
oxythiamine KYSE-140 CTRP1 0.2603 33.3330
oxythiamine KYSE-410 CTRP1 0.2603 33.3330
oxythiamine KYSE-450 CTRP1 0.2603 33.3330
oxythiamine COV318 CTRP1 0.2603 33.3330
oxythiamine EFO-21 CTRP1 0.2603 33.3330
oxythiamine HEYA8 CTRP1 0.2603 33.3330
oxythiamine JHOS-4 CTRP1 0.2603 33.3330
oxythiamine OVMANA CTRP1 0.2603 33.3330
oxythiamine SK-OV-3 CTRP1 0.2603 33.3330
oxythiamine CAPAN-2 CTRP1 0.2603 33.3330
oxythiamine HUP-T4 CTRP1 0.2603 33.3330
oxythiamine KP-3 CTRP1 0.2603 33.3330
oxythiamine PANC03.27 CTRP1 0.2603 33.3330
oxythiamine PATU8902 CTRP1 0.2603 33.3330
oxythiamine QGP-1 CTRP1 0.2603 33.3330
oxythiamine SUIT-2 CTRP1 0.2603 33.3330
oxythiamine MSTO-211H CTRP1 0.2603 33.3330
oxythiamine NCI-H2052 CTRP1 0.2603 33.3330
oxythiamine NCI-H28 CTRP1 0.2603 33.3330
oxythiamine MIAPACA-3 CTRP1 0.2603 33.3330
oxythiamine G-361 CTRP1 0.2603 33.3330
oxythiamine HS852.T CTRP1 0.2603 33.3330
oxythiamine HS936.T CTRP1 0.2603 33.3330
oxythiamine HS944.T CTRP1 0.2603 33.3330
oxythiamine G-401 CTRP1 0.2603 33.3330
oxythiamine FU97 CTRP1 0.2603 33.3330
oxythiamine KE-97 CTRP1 0.2603 33.3330
oxythiamine MKN7 CTRP1 0.2603 33.3330
oxythiamine MKN74 CTRP1 0.2603 33.3330
oxythiamine NUGC-4 CTRP1 0.2603 33.3330
oxythiamine SH-10-TC CTRP1 0.2603 33.3330
oxythiamine HSC-2 CTRP1 0.2603 33.3330
oxythiamine 5637 CTRP1 0.2603 33.3330
oxythiamine HT-1376 CTRP1 0.2603 33.3330
oxythiamine KMBC-2 CTRP1 0.2603 33.3330
oxythiamine RT-4 CTRP1 0.2603 33.3330
oxythiamine UM-UC-3 CTRP1 0.2603 33.3330

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Cell lines with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Cell lines with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Cell lines with highest and lowest AUC

Associated Genes (Mutation)

Genes with the largest and lowest Racksum’s effect sizes, calculated by comparing IC50 between the mutant and wide type cell lines using cell lines from pancan data.

Associated Genes (Gene Expression)

Genes with the highest and lowest Spearman correlations, calculated by comparing gene expression and IC50 across cell lines from pancan data.