Drug : Iso-Dc-45-A2

CTRP1 Name : iso-DC-45-A2

Dataset : All
Synonyms :
Targets :
Pathways : trioxacarcin natural product analog

Information Cards

Click to show/hide information cards below or download all drug response information.

           
     

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including drug name, cell line name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Drug name Cellosaurus ID Original Dataset(s) Min Dose Max Dose Dose-response
iso-DC-45-A2 GAMG CTRP1 0.2603 33.3330
iso-DC-45-A2 SF295 CTRP1 0.2603 33.3330
iso-DC-45-A2 HEC-108 CTRP1 0.2603 33.3330
iso-DC-45-A2 HEC-251 CTRP1 0.2603 33.3330
iso-DC-45-A2 HEC-265 CTRP1 0.2603 33.3330
iso-DC-45-A2 HEC-59 CTRP1 0.2603 33.3330
iso-DC-45-A2 HEC-6 CTRP1 0.2603 33.3330
iso-DC-45-A2 ISHIKAWA(HERAKLIO)02ER- CTRP1 0.2603 33.3330
iso-DC-45-A2 KLE CTRP1 0.2603 33.3330
iso-DC-45-A2 MFE-319 CTRP1 0.2603 33.3330
iso-DC-45-A2 SNG-M CTRP1 0.2603 33.3330
iso-DC-45-A2 BL-70 CTRP1 0.2603 33.3330
iso-DC-45-A2 HT CTRP1 0.2603 33.3330
iso-DC-45-A2 KU812 CTRP1 0.2603 33.3330
iso-DC-45-A2 MC116 CTRP1 0.2603 33.3330
iso-DC-45-A2 P3HR-1 CTRP1 0.2603 33.3330
iso-DC-45-A2 VMRC-RCW CTRP1 0.2603 33.3330
iso-DC-45-A2 C2BBE1 CTRP1 0.2603 33.3330
iso-DC-45-A2 COLO205 CTRP1 0.2603 33.3330
iso-DC-45-A2 DLD-1 CTRP1 0.2603 33.3330
iso-DC-45-A2 GP2D CTRP1 0.2603 33.3330
iso-DC-45-A2 LS411N CTRP1 0.2603 33.3330
iso-DC-45-A2 LS513 CTRP1 0.2603 33.3330
iso-DC-45-A2 SK-CO-1 CTRP1 0.2603 33.3330
iso-DC-45-A2 SNU-C2A CTRP1 0.2603 33.3330
iso-DC-45-A2 SW403 CTRP1 0.2603 33.3330
iso-DC-45-A2 SW48 CTRP1 0.2603 33.3330
iso-DC-45-A2 JHH-6 CTRP1 0.2603 33.3330
iso-DC-45-A2 SNU-449 CTRP1 0.2603 33.3330
iso-DC-45-A2 A-549 CTRP1 0.2603 33.3330
iso-DC-45-A2 BEN CTRP1 0.2603 33.3330
iso-DC-45-A2 CALU-3 CTRP1 0.2603 33.3330
iso-DC-45-A2 CALU-6 CTRP1 0.2603 33.3330
iso-DC-45-A2 CHAGO-K-1 CTRP1 0.2603 33.3330
iso-DC-45-A2 COLO668 CTRP1 0.2603 33.3330
iso-DC-45-A2 COR-L279 CTRP1 0.2603 33.3330
iso-DC-45-A2 COR-L88 CTRP1 0.2603 33.3330
iso-DC-45-A2 DMS273 CTRP1 0.2603 33.3330
iso-DC-45-A2 DV-90 CTRP1 0.2603 33.3330
iso-DC-45-A2 EBC-1 CTRP1 0.2603 33.3330
iso-DC-45-A2 EPLC-272H CTRP1 0.2603 33.3330
iso-DC-45-A2 HARA[HUMANSQUAMOUSCELLLUNGCARCINOMA] CTRP1 0.2603 33.3330
iso-DC-45-A2 HCC33 CTRP1 0.2603 33.3330
iso-DC-45-A2 HCC44 CTRP1 0.2603 33.3330
iso-DC-45-A2 HCC78 CTRP1 0.2603 33.3330
iso-DC-45-A2 KNS-62 CTRP1 0.2603 33.3330
iso-DC-45-A2 LC-1-SQ-SF CTRP1 0.2603 33.3330
iso-DC-45-A2 LCLC-103H CTRP1 0.2603 33.3330
iso-DC-45-A2 LCLC-97TM1 CTRP1 0.2603 33.3330
iso-DC-45-A2 LU-65 CTRP1 0.2603 33.3330
iso-DC-45-A2 LU-99 CTRP1 0.2603 33.3330
iso-DC-45-A2 LXF289 CTRP1 0.2603 33.3330
iso-DC-45-A2 NCI-H1048 CTRP1 0.2603 33.3330
iso-DC-45-A2 NCI-H1299 CTRP1 0.2603 33.3330
iso-DC-45-A2 NCI-H1355 CTRP1 0.2603 33.3330
iso-DC-45-A2 NCI-H1373 CTRP1 0.2603 33.3330
iso-DC-45-A2 NCI-H1435 CTRP1 0.2603 33.3330
iso-DC-45-A2 NCI-H1437 CTRP1 0.2603 33.3330
iso-DC-45-A2 NCI-H1568 CTRP1 0.2603 33.3330
iso-DC-45-A2 NCI-H1573 CTRP1 0.2603 33.3330
iso-DC-45-A2 NCI-H1666 CTRP1 0.2603 33.3330
iso-DC-45-A2 NCI-H1792 CTRP1 0.2603 33.3330
iso-DC-45-A2 NCI-H1793 CTRP1 0.2603 33.3330
iso-DC-45-A2 NCI-H1915 CTRP1 0.2603 33.3330
iso-DC-45-A2 NCI-H1930 CTRP1 0.2603 33.3330
iso-DC-45-A2 NCI-H1944 CTRP1 0.2603 33.3330
iso-DC-45-A2 NCI-H1975 CTRP1 0.2603 33.3330
iso-DC-45-A2 NCI-H2009 CTRP1 0.2603 33.3330
iso-DC-45-A2 NCI-H2029 CTRP1 0.2603 33.3330
iso-DC-45-A2 NCI-H2126 CTRP1 0.2603 33.3330
iso-DC-45-A2 NCI-H2286 CTRP1 0.2603 33.3330
iso-DC-45-A2 NCI-H23 CTRP1 0.2603 33.3330
iso-DC-45-A2 NCI-H2405 CTRP1 0.2603 33.3330
iso-DC-45-A2 NCI-H358 CTRP1 0.2603 33.3330
iso-DC-45-A2 NCI-H522 CTRP1 0.2603 33.3330
iso-DC-45-A2 NCI-H650 CTRP1 0.2603 33.3330
iso-DC-45-A2 NCI-H661 CTRP1 0.2603 33.3330
iso-DC-45-A2 NCI-H727 CTRP1 0.2603 33.3330
iso-DC-45-A2 NCI-H810 CTRP1 0.2603 33.3330
iso-DC-45-A2 NCI-H82 CTRP1 0.2603 33.3330
iso-DC-45-A2 RERF-LC-KJ CTRP1 0.2603 33.3330
iso-DC-45-A2 SHP-77 CTRP1 0.2603 33.3330
iso-DC-45-A2 VMRC-LCD CTRP1 0.2603 33.3330
iso-DC-45-A2 KYSE-140 CTRP1 0.2603 33.3330
iso-DC-45-A2 KYSE-410 CTRP1 0.2603 33.3330
iso-DC-45-A2 KYSE-450 CTRP1 0.2603 33.3330
iso-DC-45-A2 COV318 CTRP1 0.2603 33.3330
iso-DC-45-A2 EFO-21 CTRP1 0.2603 33.3330
iso-DC-45-A2 HEYA8 CTRP1 0.2603 33.3330
iso-DC-45-A2 JHOS-4 CTRP1 0.2603 33.3330
iso-DC-45-A2 OVMANA CTRP1 0.2603 33.3330
iso-DC-45-A2 SK-OV-3 CTRP1 0.2603 33.3330
iso-DC-45-A2 CAPAN-2 CTRP1 0.2603 33.3330
iso-DC-45-A2 CFPAC-1 CTRP1 0.2603 33.3330
iso-DC-45-A2 HPAC CTRP1 0.2603 33.3330
iso-DC-45-A2 HUP-T4 CTRP1 0.2603 33.3330
iso-DC-45-A2 KP-3 CTRP1 0.2603 33.3330
iso-DC-45-A2 PANC03.27 CTRP1 0.2603 33.3330
iso-DC-45-A2 PANC10.05 CTRP1 0.2603 33.3330
iso-DC-45-A2 PATU8902 CTRP1 0.2603 33.3330
iso-DC-45-A2 QGP-1 CTRP1 0.2603 33.3330
iso-DC-45-A2 SUIT-2 CTRP1 0.2603 33.3330
iso-DC-45-A2 MSTO-211H CTRP1 0.2603 33.3330
iso-DC-45-A2 NCI-H2052 CTRP1 0.2603 33.3330
iso-DC-45-A2 NCI-H28 CTRP1 0.2603 33.3330
iso-DC-45-A2 MIAPACA-3 CTRP1 0.2603 33.3330
iso-DC-45-A2 COLO741 CTRP1 0.2603 33.3330
iso-DC-45-A2 G-361 CTRP1 0.2603 33.3330
iso-DC-45-A2 HS852.T CTRP1 0.2603 33.3330
iso-DC-45-A2 HS936.T CTRP1 0.2603 33.3330
iso-DC-45-A2 HS944.T CTRP1 0.2603 33.3330
iso-DC-45-A2 G-401 CTRP1 0.2603 33.3330
iso-DC-45-A2 FU97 CTRP1 0.2603 33.3330
iso-DC-45-A2 KE-97 CTRP1 0.2603 33.3330
iso-DC-45-A2 MKN7 CTRP1 0.2603 33.3330
iso-DC-45-A2 MKN74 CTRP1 0.2603 33.3330
iso-DC-45-A2 NUGC-4 CTRP1 0.2603 33.3330
iso-DC-45-A2 SH-10-TC CTRP1 0.2603 33.3330
iso-DC-45-A2 HSC-2 CTRP1 0.2603 33.3330
iso-DC-45-A2 5637 CTRP1 0.2603 33.3330
iso-DC-45-A2 HT-1376 CTRP1 0.2603 33.3330
iso-DC-45-A2 KMBC-2 CTRP1 0.2603 33.3330
iso-DC-45-A2 RT-4 CTRP1 0.2603 33.3330
iso-DC-45-A2 UM-UC-3 CTRP1 0.2603 33.3330

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Cell lines with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Cell lines with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Cell lines with highest and lowest AUC

Associated Genes (Mutation)

Genes with the largest and lowest Racksum’s effect sizes, calculated by comparing IC50 between the mutant and wide type cell lines using cell lines from pancan data.

Associated Genes (Gene Expression)

Genes with the highest and lowest Spearman correlations, calculated by comparing gene expression and IC50 across cell lines from pancan data.