Drug : Fosfomycin

CTRP1 Name : fosfomycin

Dataset : All
Synonyms :
Targets : PKM;DPAGT1
Pathways : inhibitor of pyruvate kinase;inhibitor of MurA (UDP-N-acetylglucosamine Enolpyruvyl Transferase)

Information Cards

Click to show/hide information cards below or download all drug response information.

           
     

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including drug name, cell line name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Drug name Cellosaurus ID Original Dataset(s) Min Dose Max Dose Dose-response
fosfomycin GAMG CTRP1 0.2603 33.3330
fosfomycin SF295 CTRP1 0.2603 33.3330
fosfomycin HEC-108 CTRP1 0.2603 33.3330
fosfomycin HEC-251 CTRP1 0.2603 33.3330
fosfomycin HEC-265 CTRP1 0.2603 33.3330
fosfomycin HEC-59 CTRP1 0.2603 33.3330
fosfomycin HEC-6 CTRP1 0.2603 33.3330
fosfomycin ISHIKAWA(HERAKLIO)02ER- CTRP1 0.2603 33.3330
fosfomycin KLE CTRP1 0.2603 33.3330
fosfomycin MFE-319 CTRP1 0.2603 33.3330
fosfomycin SNG-M CTRP1 0.2603 33.3330
fosfomycin BL-70 CTRP1 0.2603 33.3330
fosfomycin HT CTRP1 0.2603 33.3330
fosfomycin KU812 CTRP1 0.2603 33.3330
fosfomycin MC116 CTRP1 0.2603 33.3330
fosfomycin P3HR-1 CTRP1 0.2603 33.3330
fosfomycin VMRC-RCW CTRP1 0.2603 33.3330
fosfomycin C2BBE1 CTRP1 0.2603 33.3330
fosfomycin COLO205 CTRP1 0.2603 33.3330
fosfomycin DLD-1 CTRP1 0.2603 33.3330
fosfomycin GP2D CTRP1 0.2603 33.3330
fosfomycin LS411N CTRP1 0.2603 33.3330
fosfomycin LS513 CTRP1 0.2603 33.3330
fosfomycin SK-CO-1 CTRP1 0.2603 33.3330
fosfomycin SNU-C2A CTRP1 0.2603 33.3330
fosfomycin SW403 CTRP1 0.2603 33.3330
fosfomycin SW48 CTRP1 0.2603 33.3330
fosfomycin JHH-6 CTRP1 0.2603 33.3330
fosfomycin SNU-449 CTRP1 0.2603 33.3330
fosfomycin A-549 CTRP1 0.2603 33.3330
fosfomycin BEN CTRP1 0.2603 33.3330
fosfomycin CALU-3 CTRP1 0.2603 33.3330
fosfomycin CALU-6 CTRP1 0.2603 33.3330
fosfomycin CHAGO-K-1 CTRP1 0.2603 33.3330
fosfomycin COLO668 CTRP1 0.2603 33.3330
fosfomycin COR-L279 CTRP1 0.2603 33.3330
fosfomycin COR-L88 CTRP1 0.2603 33.3330
fosfomycin DMS273 CTRP1 0.2603 33.3330
fosfomycin DV-90 CTRP1 0.2603 33.3330
fosfomycin EBC-1 CTRP1 0.2603 33.3330
fosfomycin EPLC-272H CTRP1 0.2603 33.3330
fosfomycin HARA[HUMANSQUAMOUSCELLLUNGCARCINOMA] CTRP1 0.2603 33.3330
fosfomycin HCC33 CTRP1 0.2603 33.3330
fosfomycin HCC44 CTRP1 0.2603 33.3330
fosfomycin HCC78 CTRP1 0.2603 33.3330
fosfomycin KNS-62 CTRP1 0.2603 33.3330
fosfomycin LC-1-SQ-SF CTRP1 0.2603 33.3330
fosfomycin LCLC-103H CTRP1 0.2603 33.3330
fosfomycin LCLC-97TM1 CTRP1 0.2603 33.3330
fosfomycin LU-65 CTRP1 0.2603 33.3330
fosfomycin LU-99 CTRP1 0.2603 33.3330
fosfomycin LXF289 CTRP1 0.2603 33.3330
fosfomycin NCI-H1048 CTRP1 0.2603 33.3330
fosfomycin NCI-H1299 CTRP1 0.2603 33.3330
fosfomycin NCI-H1355 CTRP1 0.2603 33.3330
fosfomycin NCI-H1373 CTRP1 0.2603 33.3330
fosfomycin NCI-H1435 CTRP1 0.2603 33.3330
fosfomycin NCI-H1437 CTRP1 0.2603 33.3330
fosfomycin NCI-H1568 CTRP1 0.2603 33.3330
fosfomycin NCI-H1573 CTRP1 0.2603 33.3330
fosfomycin NCI-H1666 CTRP1 0.2603 33.3330
fosfomycin NCI-H1792 CTRP1 0.2603 33.3330
fosfomycin NCI-H1793 CTRP1 0.2603 33.3330
fosfomycin NCI-H1915 CTRP1 0.2603 33.3330
fosfomycin NCI-H1930 CTRP1 0.2603 33.3330
fosfomycin NCI-H1944 CTRP1 0.2603 33.3330
fosfomycin NCI-H1975 CTRP1 0.2603 33.3330
fosfomycin NCI-H2009 CTRP1 0.2603 33.3330
fosfomycin NCI-H2029 CTRP1 0.2603 33.3330
fosfomycin NCI-H2126 CTRP1 0.2603 33.3330
fosfomycin NCI-H2286 CTRP1 0.2603 33.3330
fosfomycin NCI-H23 CTRP1 0.2603 33.3330
fosfomycin NCI-H2405 CTRP1 0.2603 33.3330
fosfomycin NCI-H358 CTRP1 0.2603 33.3330
fosfomycin NCI-H522 CTRP1 0.2603 33.3330
fosfomycin NCI-H650 CTRP1 0.2603 33.3330
fosfomycin NCI-H661 CTRP1 0.2603 33.3330
fosfomycin NCI-H727 CTRP1 0.2603 33.3330
fosfomycin NCI-H810 CTRP1 0.2603 33.3330
fosfomycin NCI-H82 CTRP1 0.2603 33.3330
fosfomycin RERF-LC-KJ CTRP1 0.2603 33.3330
fosfomycin SHP-77 CTRP1 0.2603 33.3330
fosfomycin VMRC-LCD CTRP1 0.2603 33.3330
fosfomycin KYSE-140 CTRP1 0.2603 33.3330
fosfomycin KYSE-410 CTRP1 0.2603 33.3330
fosfomycin KYSE-450 CTRP1 0.2603 33.3330
fosfomycin COV318 CTRP1 0.2603 33.3330
fosfomycin EFO-21 CTRP1 0.2603 33.3330
fosfomycin HEYA8 CTRP1 0.2603 33.3330
fosfomycin JHOS-4 CTRP1 0.2603 33.3330
fosfomycin OVMANA CTRP1 0.2603 33.3330
fosfomycin SK-OV-3 CTRP1 0.2603 33.3330
fosfomycin CAPAN-2 CTRP1 0.2603 33.3330
fosfomycin CFPAC-1 CTRP1 0.2603 33.3330
fosfomycin HPAC CTRP1 0.2603 33.3330
fosfomycin HUP-T4 CTRP1 0.2603 33.3330
fosfomycin KP-3 CTRP1 0.2603 33.3330
fosfomycin PANC03.27 CTRP1 0.2603 33.3330
fosfomycin PANC10.05 CTRP1 0.2603 33.3330
fosfomycin PATU8902 CTRP1 0.2603 33.3330
fosfomycin QGP-1 CTRP1 0.2603 33.3330
fosfomycin SUIT-2 CTRP1 0.2603 33.3330
fosfomycin MSTO-211H CTRP1 0.2603 33.3330
fosfomycin NCI-H2052 CTRP1 0.2603 33.3330
fosfomycin NCI-H28 CTRP1 0.2603 33.3330
fosfomycin MIAPACA-3 CTRP1 0.2603 33.3330
fosfomycin COLO741 CTRP1 0.2603 33.3330
fosfomycin G-361 CTRP1 0.2603 33.3330
fosfomycin HS852.T CTRP1 0.2603 33.3330
fosfomycin HS936.T CTRP1 0.2603 33.3330
fosfomycin HS944.T CTRP1 0.2603 33.3330
fosfomycin G-401 CTRP1 0.2603 33.3330
fosfomycin FU97 CTRP1 0.2603 33.3330
fosfomycin KE-97 CTRP1 0.2603 33.3330
fosfomycin MKN7 CTRP1 0.2603 33.3330
fosfomycin MKN74 CTRP1 0.2603 33.3330
fosfomycin NUGC-4 CTRP1 0.2603 33.3330
fosfomycin SH-10-TC CTRP1 0.2603 33.3330
fosfomycin HSC-2 CTRP1 0.2603 33.3330
fosfomycin 5637 CTRP1 0.2603 33.3330
fosfomycin HT-1376 CTRP1 0.2603 33.3330
fosfomycin KMBC-2 CTRP1 0.2603 33.3330
fosfomycin RT-4 CTRP1 0.2603 33.3330
fosfomycin UM-UC-3 CTRP1 0.2603 33.3330

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Cell lines with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Cell lines with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Cell lines with highest and lowest AUC

Associated Genes (Mutation)

Genes with the largest and lowest Racksum’s effect sizes, calculated by comparing IC50 between the mutant and wide type cell lines using cell lines from pancan data.

Associated Genes (Gene Expression)

Genes with the highest and lowest Spearman correlations, calculated by comparing gene expression and IC50 across cell lines from pancan data.