Drug : Eflornithine

CTRP1 Name : eflornithine

Dataset : All
Synonyms :
Targets : ODC1
Pathways : inhibitor of ornithine decarboxylase

Information Cards

Click to show/hide information cards below or download all drug response information.

           
     

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including drug name, cell line name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Drug name Cellosaurus ID Original Dataset(s) Min Dose Max Dose Dose-response
eflornithine GAMG CTRP1 0.2890 37.0000
eflornithine SF295 CTRP1 0.2890 37.0000
eflornithine HEC-108 CTRP1 0.2890 37.0000
eflornithine HEC-251 CTRP1 0.2890 37.0000
eflornithine HEC-265 CTRP1 0.2890 37.0000
eflornithine HEC-59 CTRP1 0.2890 37.0000
eflornithine HEC-6 CTRP1 0.2890 37.0000
eflornithine ISHIKAWA(HERAKLIO)02ER- CTRP1 0.2890 37.0000
eflornithine KLE CTRP1 0.2890 37.0000
eflornithine MFE-319 CTRP1 0.2890 37.0000
eflornithine SNG-M CTRP1 0.2890 37.0000
eflornithine BL-70 CTRP1 0.2890 37.0000
eflornithine HT CTRP1 0.2890 37.0000
eflornithine KU812 CTRP1 0.2890 37.0000
eflornithine MC116 CTRP1 0.2890 37.0000
eflornithine P3HR-1 CTRP1 0.2890 37.0000
eflornithine VMRC-RCW CTRP1 0.2890 37.0000
eflornithine C2BBE1 CTRP1 0.2890 37.0000
eflornithine COLO205 CTRP1 0.2890 37.0000
eflornithine DLD-1 CTRP1 0.2890 37.0000
eflornithine GP2D CTRP1 0.2890 37.0000
eflornithine LS411N CTRP1 0.2890 37.0000
eflornithine LS513 CTRP1 0.2890 37.0000
eflornithine SK-CO-1 CTRP1 0.2890 37.0000
eflornithine SNU-C2A CTRP1 0.2890 37.0000
eflornithine SW403 CTRP1 0.2890 37.0000
eflornithine SW48 CTRP1 0.2890 37.0000
eflornithine JHH-6 CTRP1 0.2890 37.0000
eflornithine SNU-449 CTRP1 0.2890 37.0000
eflornithine A-549 CTRP1 0.2890 37.0000
eflornithine BEN CTRP1 0.2890 37.0000
eflornithine CALU-3 CTRP1 0.2890 37.0000
eflornithine CALU-6 CTRP1 0.2890 37.0000
eflornithine CHAGO-K-1 CTRP1 0.2890 37.0000
eflornithine COLO668 CTRP1 0.2890 37.0000
eflornithine COR-L279 CTRP1 0.2890 37.0000
eflornithine COR-L88 CTRP1 0.2890 37.0000
eflornithine DMS273 CTRP1 0.2890 37.0000
eflornithine DV-90 CTRP1 0.2890 37.0000
eflornithine EBC-1 CTRP1 0.2890 37.0000
eflornithine EPLC-272H CTRP1 0.2890 37.0000
eflornithine HARA[HUMANSQUAMOUSCELLLUNGCARCINOMA] CTRP1 0.2890 37.0000
eflornithine HCC33 CTRP1 0.2890 37.0000
eflornithine HCC44 CTRP1 0.2890 37.0000
eflornithine HCC78 CTRP1 0.2890 37.0000
eflornithine KNS-62 CTRP1 0.2890 37.0000
eflornithine LC-1-SQ-SF CTRP1 0.2890 37.0000
eflornithine LCLC-103H CTRP1 0.2890 37.0000
eflornithine LCLC-97TM1 CTRP1 0.2890 37.0000
eflornithine LU-65 CTRP1 0.2890 37.0000
eflornithine LU-99 CTRP1 0.2890 37.0000
eflornithine LXF289 CTRP1 0.2890 37.0000
eflornithine NCI-H1048 CTRP1 0.2890 37.0000
eflornithine NCI-H1299 CTRP1 0.2890 37.0000
eflornithine NCI-H1355 CTRP1 0.2890 37.0000
eflornithine NCI-H1373 CTRP1 0.2890 37.0000
eflornithine NCI-H1435 CTRP1 0.2890 37.0000
eflornithine NCI-H1437 CTRP1 0.2890 37.0000
eflornithine NCI-H1568 CTRP1 0.2890 37.0000
eflornithine NCI-H1573 CTRP1 0.2890 37.0000
eflornithine NCI-H1666 CTRP1 0.2890 37.0000
eflornithine NCI-H1792 CTRP1 0.2890 37.0000
eflornithine NCI-H1793 CTRP1 0.2890 37.0000
eflornithine NCI-H1915 CTRP1 0.2890 37.0000
eflornithine NCI-H1930 CTRP1 0.2890 37.0000
eflornithine NCI-H1944 CTRP1 0.2890 37.0000
eflornithine NCI-H1975 CTRP1 0.2890 37.0000
eflornithine NCI-H2009 CTRP1 0.2890 37.0000
eflornithine NCI-H2029 CTRP1 0.2890 37.0000
eflornithine NCI-H2126 CTRP1 0.2890 37.0000
eflornithine NCI-H2286 CTRP1 0.2890 37.0000
eflornithine NCI-H23 CTRP1 0.2890 37.0000
eflornithine NCI-H2405 CTRP1 0.2890 37.0000
eflornithine NCI-H358 CTRP1 0.2890 37.0000
eflornithine NCI-H522 CTRP1 0.2890 37.0000
eflornithine NCI-H650 CTRP1 0.2890 37.0000
eflornithine NCI-H661 CTRP1 0.2890 37.0000
eflornithine NCI-H727 CTRP1 0.2890 37.0000
eflornithine NCI-H810 CTRP1 0.2890 37.0000
eflornithine NCI-H82 CTRP1 0.2890 37.0000
eflornithine RERF-LC-KJ CTRP1 0.2890 37.0000
eflornithine SHP-77 CTRP1 0.2890 37.0000
eflornithine VMRC-LCD CTRP1 0.2890 37.0000
eflornithine KYSE-140 CTRP1 0.2890 37.0000
eflornithine KYSE-410 CTRP1 0.2890 37.0000
eflornithine KYSE-450 CTRP1 0.2890 37.0000
eflornithine COV318 CTRP1 0.2890 37.0000
eflornithine EFO-21 CTRP1 0.2890 37.0000
eflornithine HEYA8 CTRP1 0.2890 37.0000
eflornithine JHOS-4 CTRP1 0.2890 37.0000
eflornithine OVMANA CTRP1 0.2890 37.0000
eflornithine SK-OV-3 CTRP1 0.2890 37.0000
eflornithine CAPAN-2 CTRP1 0.2890 37.0000
eflornithine CFPAC-1 CTRP1 0.2890 37.0000
eflornithine HPAC CTRP1 0.2890 37.0000
eflornithine HUP-T4 CTRP1 0.2890 37.0000
eflornithine KP-3 CTRP1 0.2890 37.0000
eflornithine PANC03.27 CTRP1 0.2890 37.0000
eflornithine PANC10.05 CTRP1 0.2890 37.0000
eflornithine PATU8902 CTRP1 0.2890 37.0000
eflornithine QGP-1 CTRP1 0.2890 37.0000
eflornithine SUIT-2 CTRP1 0.2890 37.0000
eflornithine MSTO-211H CTRP1 0.2890 37.0000
eflornithine NCI-H2052 CTRP1 0.2890 37.0000
eflornithine NCI-H28 CTRP1 0.2890 37.0000
eflornithine MIAPACA-3 CTRP1 0.2890 37.0000
eflornithine COLO741 CTRP1 0.2890 37.0000
eflornithine G-361 CTRP1 0.2890 37.0000
eflornithine HS852.T CTRP1 0.2890 37.0000
eflornithine HS936.T CTRP1 0.2890 37.0000
eflornithine HS944.T CTRP1 0.2890 37.0000
eflornithine G-401 CTRP1 0.2890 37.0000
eflornithine FU97 CTRP1 0.2890 37.0000
eflornithine KE-97 CTRP1 0.2890 37.0000
eflornithine MKN7 CTRP1 0.2890 37.0000
eflornithine MKN74 CTRP1 0.2890 37.0000
eflornithine NUGC-4 CTRP1 0.2890 37.0000
eflornithine SH-10-TC CTRP1 0.2890 37.0000
eflornithine HSC-2 CTRP1 0.2890 37.0000
eflornithine 5637 CTRP1 0.2890 37.0000
eflornithine HT-1376 CTRP1 0.2890 37.0000
eflornithine KMBC-2 CTRP1 0.2890 37.0000
eflornithine RT-4 CTRP1 0.2890 37.0000
eflornithine UM-UC-3 CTRP1 0.2890 37.0000

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Cell lines with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Cell lines with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Cell lines with highest and lowest AUC

Associated Genes (Mutation)

Genes with the largest and lowest Racksum’s effect sizes, calculated by comparing IC50 between the mutant and wide type cell lines using cell lines from pancan data.

Associated Genes (Gene Expression)

Genes with the highest and lowest Spearman correlations, calculated by comparing gene expression and IC50 across cell lines from pancan data.