Drug : Aspirin

CTRP1 Name : aspirin

Dataset : All
Synonyms :
Targets : PTGS1;PTGS2
Pathways : inhibitor of cyclooxygenase 1 (COX1) and 2 (COX2)

Information Cards

Click to show/hide information cards below or download all drug response information.

           
     

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including drug name, cell line name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Drug name Cellosaurus ID Original Dataset(s) Min Dose Max Dose Dose-response
aspirin GAMG CTRP1 0.2603 33.3330
aspirin SF295 CTRP1 0.2603 33.3330
aspirin HEC-108 CTRP1 0.2603 33.3330
aspirin HEC-251 CTRP1 0.2603 33.3330
aspirin HEC-265 CTRP1 0.2603 33.3330
aspirin HEC-59 CTRP1 0.2603 33.3330
aspirin HEC-6 CTRP1 0.2603 33.3330
aspirin ISHIKAWA(HERAKLIO)02ER- CTRP1 0.2603 33.3330
aspirin KLE CTRP1 0.2603 33.3330
aspirin MFE-319 CTRP1 0.2603 33.3330
aspirin SNG-M CTRP1 0.2603 33.3330
aspirin BL-70 CTRP1 0.2603 33.3330
aspirin HT CTRP1 0.2603 33.3330
aspirin KU812 CTRP1 0.2603 33.3330
aspirin MC116 CTRP1 0.2603 33.3330
aspirin P3HR-1 CTRP1 0.2603 33.3330
aspirin VMRC-RCW CTRP1 0.2603 33.3330
aspirin C2BBE1 CTRP1 0.2603 33.3330
aspirin COLO205 CTRP1 0.2603 33.3330
aspirin DLD-1 CTRP1 0.2603 33.3330
aspirin GP2D CTRP1 0.2603 33.3330
aspirin LS411N CTRP1 0.2603 33.3330
aspirin LS513 CTRP1 0.2603 33.3330
aspirin SK-CO-1 CTRP1 0.2603 33.3330
aspirin SNU-C2A CTRP1 0.2603 33.3330
aspirin SW403 CTRP1 0.2603 33.3330
aspirin SW48 CTRP1 0.2603 33.3330
aspirin JHH-6 CTRP1 0.2603 33.3330
aspirin SNU-449 CTRP1 0.2603 33.3330
aspirin A-549 CTRP1 0.2603 33.3330
aspirin BEN CTRP1 0.2603 33.3330
aspirin CALU-3 CTRP1 0.2603 33.3330
aspirin CALU-6 CTRP1 0.2603 33.3330
aspirin CHAGO-K-1 CTRP1 0.2603 33.3330
aspirin COLO668 CTRP1 0.2603 33.3330
aspirin COR-L279 CTRP1 0.2603 33.3330
aspirin COR-L88 CTRP1 0.2603 33.3330
aspirin DMS273 CTRP1 0.2603 33.3330
aspirin DV-90 CTRP1 0.2603 33.3330
aspirin EBC-1 CTRP1 0.2603 33.3330
aspirin EPLC-272H CTRP1 0.2603 33.3330
aspirin HARA[HUMANSQUAMOUSCELLLUNGCARCINOMA] CTRP1 0.2603 33.3330
aspirin HCC33 CTRP1 0.2603 33.3330
aspirin HCC44 CTRP1 0.2603 33.3330
aspirin HCC78 CTRP1 0.2603 33.3330
aspirin KNS-62 CTRP1 0.2603 33.3330
aspirin LC-1-SQ-SF CTRP1 0.2603 33.3330
aspirin LCLC-103H CTRP1 0.2603 33.3330
aspirin LCLC-97TM1 CTRP1 0.2603 33.3330
aspirin LU-65 CTRP1 0.2603 33.3330
aspirin LU-99 CTRP1 0.2603 33.3330
aspirin LXF289 CTRP1 0.2603 33.3330
aspirin NCI-H1048 CTRP1 0.2603 33.3330
aspirin NCI-H1299 CTRP1 0.2603 33.3330
aspirin NCI-H1355 CTRP1 0.2603 33.3330
aspirin NCI-H1373 CTRP1 0.2603 33.3330
aspirin NCI-H1435 CTRP1 0.2603 33.3330
aspirin NCI-H1437 CTRP1 0.2603 33.3330
aspirin NCI-H1568 CTRP1 0.2603 33.3330
aspirin NCI-H1573 CTRP1 0.2603 33.3330
aspirin NCI-H1666 CTRP1 0.2603 33.3330
aspirin NCI-H1792 CTRP1 0.2603 33.3330
aspirin NCI-H1793 CTRP1 0.2603 33.3330
aspirin NCI-H1915 CTRP1 0.2603 33.3330
aspirin NCI-H1930 CTRP1 0.2603 33.3330
aspirin NCI-H1944 CTRP1 0.2603 33.3330
aspirin NCI-H1975 CTRP1 0.2603 33.3330
aspirin NCI-H2009 CTRP1 0.2603 33.3330
aspirin NCI-H2029 CTRP1 0.2603 33.3330
aspirin NCI-H2126 CTRP1 0.2603 33.3330
aspirin NCI-H2286 CTRP1 0.2603 33.3330
aspirin NCI-H23 CTRP1 0.2603 33.3330
aspirin NCI-H2405 CTRP1 0.2603 33.3330
aspirin NCI-H358 CTRP1 0.2603 33.3330
aspirin NCI-H522 CTRP1 0.2603 33.3330
aspirin NCI-H650 CTRP1 0.2603 33.3330
aspirin NCI-H661 CTRP1 0.2603 33.3330
aspirin NCI-H727 CTRP1 0.2603 33.3330
aspirin NCI-H810 CTRP1 0.2603 33.3330
aspirin NCI-H82 CTRP1 0.2603 33.3330
aspirin RERF-LC-KJ CTRP1 0.2603 33.3330
aspirin SHP-77 CTRP1 0.2603 33.3330
aspirin VMRC-LCD CTRP1 0.2603 33.3330
aspirin KYSE-140 CTRP1 0.2603 33.3330
aspirin KYSE-410 CTRP1 0.2603 33.3330
aspirin KYSE-450 CTRP1 0.2603 33.3330
aspirin COV318 CTRP1 0.2603 33.3330
aspirin EFO-21 CTRP1 0.2603 33.3330
aspirin HEYA8 CTRP1 0.2603 33.3330
aspirin JHOS-4 CTRP1 0.2603 33.3330
aspirin OVMANA CTRP1 0.2603 33.3330
aspirin SK-OV-3 CTRP1 0.2603 33.3330
aspirin CAPAN-2 CTRP1 0.2603 33.3330
aspirin CFPAC-1 CTRP1 0.2603 33.3330
aspirin HPAC CTRP1 0.2603 33.3330
aspirin HUP-T4 CTRP1 0.2603 33.3330
aspirin KP-3 CTRP1 0.2603 33.3330
aspirin PANC03.27 CTRP1 0.2603 33.3330
aspirin PANC10.05 CTRP1 0.2603 33.3330
aspirin PATU8902 CTRP1 0.2603 33.3330
aspirin QGP-1 CTRP1 0.2603 33.3330
aspirin SUIT-2 CTRP1 0.2603 33.3330
aspirin MSTO-211H CTRP1 0.2603 33.3330
aspirin NCI-H2052 CTRP1 0.2603 33.3330
aspirin NCI-H28 CTRP1 0.2603 33.3330
aspirin MIAPACA-3 CTRP1 0.2603 33.3330
aspirin COLO741 CTRP1 0.2603 33.3330
aspirin G-361 CTRP1 0.2603 33.3330
aspirin HS852.T CTRP1 0.2603 33.3330
aspirin HS936.T CTRP1 0.2603 33.3330
aspirin HS944.T CTRP1 0.2603 33.3330
aspirin G-401 CTRP1 0.2603 33.3330
aspirin FU97 CTRP1 0.2603 33.3330
aspirin KE-97 CTRP1 0.2603 33.3330
aspirin MKN7 CTRP1 0.2603 33.3330
aspirin MKN74 CTRP1 0.2603 33.3330
aspirin NUGC-4 CTRP1 0.2603 33.3330
aspirin SH-10-TC CTRP1 0.2603 33.3330
aspirin HSC-2 CTRP1 0.2603 33.3330
aspirin 5637 CTRP1 0.2603 33.3330
aspirin HT-1376 CTRP1 0.2603 33.3330
aspirin KMBC-2 CTRP1 0.2603 33.3330
aspirin RT-4 CTRP1 0.2603 33.3330
aspirin UM-UC-3 CTRP1 0.2603 33.3330

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Cell lines with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Cell lines with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Cell lines with highest and lowest AUC

Associated Genes (Mutation)

Genes with the largest and lowest Racksum’s effect sizes, calculated by comparing IC50 between the mutant and wide type cell lines using cell lines from pancan data.

Associated Genes (Gene Expression)

Genes with the highest and lowest Spearman correlations, calculated by comparing gene expression and IC50 across cell lines from pancan data.