Drug : Repsox

CTRP1 Name : RepSox

Dataset : All
Synonyms :
Targets : TGFBR1
Pathways : Inhibitor of TGF? type I receptor

Information Cards

Click to show/hide information cards below or download all drug response information.

           
     

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including drug name, cell line name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Drug name Cellosaurus ID Original Dataset(s) Min Dose Max Dose Dose-response
RepSox GAMG CTRP1 0.2603 33.3330
RepSox SF295 CTRP1 0.2603 33.3330
RepSox HEC-108 CTRP1 0.2603 33.3330
RepSox HEC-251 CTRP1 0.2603 33.3330
RepSox HEC-265 CTRP1 0.2603 33.3330
RepSox HEC-59 CTRP1 0.2603 33.3330
RepSox HEC-6 CTRP1 0.2603 33.3330
RepSox ISHIKAWA(HERAKLIO)02ER- CTRP1 0.2603 33.3330
RepSox KLE CTRP1 0.2603 33.3330
RepSox MFE-319 CTRP1 0.2603 33.3330
RepSox SNG-M CTRP1 0.2603 33.3330
RepSox BL-70 CTRP1 0.2603 33.3330
RepSox HT CTRP1 0.2603 33.3330
RepSox KU812 CTRP1 0.2603 33.3330
RepSox MC116 CTRP1 0.2603 33.3330
RepSox P3HR-1 CTRP1 0.2603 33.3330
RepSox VMRC-RCW CTRP1 0.2603 33.3330
RepSox C2BBE1 CTRP1 0.2603 33.3330
RepSox COLO205 CTRP1 0.2603 33.3330
RepSox DLD-1 CTRP1 0.2603 33.3330
RepSox GP2D CTRP1 0.2603 33.3330
RepSox LS411N CTRP1 0.2603 33.3330
RepSox LS513 CTRP1 0.2603 33.3330
RepSox SK-CO-1 CTRP1 0.2603 33.3330
RepSox SNU-C2A CTRP1 0.2603 33.3330
RepSox SW403 CTRP1 0.2603 33.3330
RepSox SW48 CTRP1 0.2603 33.3330
RepSox JHH-6 CTRP1 0.2603 33.3330
RepSox SNU-449 CTRP1 0.2603 33.3330
RepSox A-549 CTRP1 0.2603 33.3330
RepSox BEN CTRP1 0.2603 33.3330
RepSox CALU-3 CTRP1 0.2603 33.3330
RepSox CALU-6 CTRP1 0.2603 33.3330
RepSox CHAGO-K-1 CTRP1 0.2603 33.3330
RepSox COLO668 CTRP1 0.2603 33.3330
RepSox COR-L279 CTRP1 0.2603 33.3330
RepSox COR-L88 CTRP1 0.2603 33.3330
RepSox DMS273 CTRP1 0.2603 33.3330
RepSox DV-90 CTRP1 0.2603 33.3330
RepSox EBC-1 CTRP1 0.2603 33.3330
RepSox EPLC-272H CTRP1 0.2603 33.3330
RepSox HARA[HUMANSQUAMOUSCELLLUNGCARCINOMA] CTRP1 0.2603 33.3330
RepSox HCC33 CTRP1 0.2603 33.3330
RepSox HCC44 CTRP1 0.2603 33.3330
RepSox HCC78 CTRP1 0.2603 33.3330
RepSox KNS-62 CTRP1 0.2603 33.3330
RepSox LC-1-SQ-SF CTRP1 0.2603 33.3330
RepSox LCLC-103H CTRP1 0.2603 33.3330
RepSox LCLC-97TM1 CTRP1 0.2603 33.3330
RepSox LU-65 CTRP1 0.2603 33.3330
RepSox LU-99 CTRP1 0.2603 33.3330
RepSox LXF289 CTRP1 0.2603 33.3330
RepSox NCI-H1048 CTRP1 0.2603 33.3330
RepSox NCI-H1299 CTRP1 0.2603 33.3330
RepSox NCI-H1355 CTRP1 0.2603 33.3330
RepSox NCI-H1373 CTRP1 0.2603 33.3330
RepSox NCI-H1435 CTRP1 0.2603 33.3330
RepSox NCI-H1437 CTRP1 0.2603 33.3330
RepSox NCI-H1568 CTRP1 0.2603 33.3330
RepSox NCI-H1573 CTRP1 0.2603 33.3330
RepSox NCI-H1666 CTRP1 0.2603 33.3330
RepSox NCI-H1792 CTRP1 0.2603 33.3330
RepSox NCI-H1793 CTRP1 0.2603 33.3330
RepSox NCI-H1915 CTRP1 0.2603 33.3330
RepSox NCI-H1930 CTRP1 0.2603 33.3330
RepSox NCI-H1944 CTRP1 0.2603 33.3330
RepSox NCI-H1975 CTRP1 0.2603 33.3330
RepSox NCI-H2009 CTRP1 0.2603 33.3330
RepSox NCI-H2029 CTRP1 0.2603 33.3330
RepSox NCI-H2126 CTRP1 0.2603 33.3330
RepSox NCI-H2286 CTRP1 0.2603 33.3330
RepSox NCI-H23 CTRP1 0.2603 33.3330
RepSox NCI-H2405 CTRP1 0.2603 33.3330
RepSox NCI-H358 CTRP1 0.2603 33.3330
RepSox NCI-H522 CTRP1 0.2603 33.3330
RepSox NCI-H650 CTRP1 0.2603 33.3330
RepSox NCI-H661 CTRP1 0.2603 33.3330
RepSox NCI-H727 CTRP1 0.2603 33.3330
RepSox NCI-H810 CTRP1 0.2603 33.3330
RepSox NCI-H82 CTRP1 0.2603 33.3330
RepSox RERF-LC-KJ CTRP1 0.2603 33.3330
RepSox SHP-77 CTRP1 0.2603 33.3330
RepSox VMRC-LCD CTRP1 0.2603 33.3330
RepSox KYSE-140 CTRP1 0.2603 33.3330
RepSox KYSE-410 CTRP1 0.2603 33.3330
RepSox KYSE-450 CTRP1 0.2603 33.3330
RepSox COV318 CTRP1 0.2603 33.3330
RepSox EFO-21 CTRP1 0.2603 33.3330
RepSox HEYA8 CTRP1 0.2603 33.3330
RepSox JHOS-4 CTRP1 0.2603 33.3330
RepSox OVMANA CTRP1 0.2603 33.3330
RepSox SK-OV-3 CTRP1 0.2603 33.3330
RepSox CAPAN-2 CTRP1 0.2603 33.3330
RepSox CFPAC-1 CTRP1 0.2603 33.3330
RepSox HPAC CTRP1 0.2603 33.3330
RepSox HUP-T4 CTRP1 0.2603 33.3330
RepSox KP-3 CTRP1 0.2603 33.3330
RepSox PANC03.27 CTRP1 0.2603 33.3330
RepSox PANC10.05 CTRP1 0.2603 33.3330
RepSox PATU8902 CTRP1 0.2603 33.3330
RepSox QGP-1 CTRP1 0.2603 33.3330
RepSox SUIT-2 CTRP1 0.2603 33.3330
RepSox MSTO-211H CTRP1 0.2603 33.3330
RepSox NCI-H2052 CTRP1 0.2603 33.3330
RepSox NCI-H28 CTRP1 0.2603 33.3330
RepSox MIAPACA-3 CTRP1 0.2603 33.3330
RepSox COLO741 CTRP1 0.2603 33.3330
RepSox G-361 CTRP1 0.2603 33.3330
RepSox HS852.T CTRP1 0.2603 33.3330
RepSox HS936.T CTRP1 0.2603 33.3330
RepSox HS944.T CTRP1 0.2603 33.3330
RepSox G-401 CTRP1 0.2603 33.3330
RepSox FU97 CTRP1 0.2603 33.3330
RepSox KE-97 CTRP1 0.2603 33.3330
RepSox MKN7 CTRP1 0.2603 33.3330
RepSox MKN74 CTRP1 0.2603 33.3330
RepSox NUGC-4 CTRP1 0.2603 33.3330
RepSox SH-10-TC CTRP1 0.2603 33.3330
RepSox HSC-2 CTRP1 0.2603 33.3330
RepSox 5637 CTRP1 0.2603 33.3330
RepSox HT-1376 CTRP1 0.2603 33.3330
RepSox KMBC-2 CTRP1 0.2603 33.3330
RepSox RT-4 CTRP1 0.2603 33.3330
RepSox UM-UC-3 CTRP1 0.2603 33.3330

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Cell lines with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Cell lines with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Cell lines with highest and lowest AUC

Associated Genes (Mutation)

Genes with the largest and lowest Racksum’s effect sizes, calculated by comparing IC50 between the mutant and wide type cell lines using cell lines from pancan data.

Associated Genes (Gene Expression)

Genes with the highest and lowest Spearman correlations, calculated by comparing gene expression and IC50 across cell lines from pancan data.