Drug : N5-Iminoethyl-L-Ornithine

CTRP1 Name : N5-iminoethyl-L-ornithine

Dataset : All
Synonyms :
Targets : NOS3
Pathways : inhibitor of endothelial nitric oxide synthase (eNOS)

Information Cards

Click to show/hide information cards below or download all drug response information.

           
     

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including drug name, cell line name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Drug name Cellosaurus ID Original Dataset(s) Min Dose Max Dose Dose-response
N5-iminoethyl-L-ornithine GAMG CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine SF295 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine HEC-108 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine HEC-251 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine HEC-265 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine HEC-59 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine HEC-6 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine ISHIKAWA(HERAKLIO)02ER- CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine KLE CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine MFE-319 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine SNG-M CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine BL-70 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine HT CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine KU812 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine MC116 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine P3HR-1 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine VMRC-RCW CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine C2BBE1 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine COLO205 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine DLD-1 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine GP2D CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine LS411N CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine LS513 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine SK-CO-1 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine SNU-C2A CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine SW403 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine SW48 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine JHH-6 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine SNU-449 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine A-549 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine BEN CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine CALU-3 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine CALU-6 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine CHAGO-K-1 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine COLO668 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine COR-L279 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine COR-L88 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine DMS273 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine DV-90 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine EBC-1 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine EPLC-272H CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine HARA[HUMANSQUAMOUSCELLLUNGCARCINOMA] CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine HCC33 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine HCC44 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine HCC78 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine KNS-62 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine LC-1-SQ-SF CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine LCLC-103H CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine LCLC-97TM1 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine LU-65 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine LU-99 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine LXF289 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine NCI-H1048 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine NCI-H1299 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine NCI-H1355 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine NCI-H1373 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine NCI-H1435 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine NCI-H1437 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine NCI-H1568 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine NCI-H1573 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine NCI-H1666 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine NCI-H1792 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine NCI-H1793 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine NCI-H1915 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine NCI-H1930 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine NCI-H1944 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine NCI-H1975 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine NCI-H2009 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine NCI-H2029 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine NCI-H2126 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine NCI-H2286 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine NCI-H23 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine NCI-H2405 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine NCI-H358 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine NCI-H522 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine NCI-H650 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine NCI-H661 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine NCI-H727 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine NCI-H810 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine NCI-H82 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine RERF-LC-KJ CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine SHP-77 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine VMRC-LCD CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine KYSE-140 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine KYSE-410 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine KYSE-450 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine COV318 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine EFO-21 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine HEYA8 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine JHOS-4 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine OVMANA CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine SK-OV-3 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine CAPAN-2 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine CFPAC-1 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine HPAC CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine HUP-T4 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine KP-3 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine PANC03.27 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine PANC10.05 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine PATU8902 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine QGP-1 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine SUIT-2 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine MSTO-211H CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine NCI-H2052 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine NCI-H28 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine MIAPACA-3 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine COLO741 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine G-361 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine HS852.T CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine HS936.T CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine HS944.T CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine G-401 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine FU97 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine KE-97 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine MKN7 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine MKN74 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine NUGC-4 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine SH-10-TC CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine HSC-2 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine 5637 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine HT-1376 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine KMBC-2 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine RT-4 CTRP1 0.2603 33.3330
N5-iminoethyl-L-ornithine UM-UC-3 CTRP1 0.2603 33.3330

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Cell lines with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Cell lines with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Cell lines with highest and lowest AUC

Associated Genes (Mutation)

Genes with the largest and lowest Racksum’s effect sizes, calculated by comparing IC50 between the mutant and wide type cell lines using cell lines from pancan data.

Associated Genes (Gene Expression)

Genes with the highest and lowest Spearman correlations, calculated by comparing gene expression and IC50 across cell lines from pancan data.