Drug : Ml039

CTRP1 Name : ML039

Dataset : All
Synonyms :
Targets : ALPL
Pathways : inhibitor of tissue non-specific alkaline phosphatase (TNAP)

Information Cards

Click to show/hide information cards below or download all drug response information.

           
     

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including drug name, cell line name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Drug name Cellosaurus ID Original Dataset(s) Min Dose Max Dose Dose-response
ML039 GAMG CTRP1 0.2603 33.3330
ML039 SF295 CTRP1 0.2603 33.3330
ML039 HEC-108 CTRP1 0.2603 33.3330
ML039 HEC-251 CTRP1 0.2603 33.3330
ML039 HEC-265 CTRP1 0.2603 33.3330
ML039 HEC-59 CTRP1 0.2603 33.3330
ML039 HEC-6 CTRP1 0.2603 33.3330
ML039 ISHIKAWA(HERAKLIO)02ER- CTRP1 0.2603 33.3330
ML039 KLE CTRP1 0.2603 33.3330
ML039 MFE-319 CTRP1 0.2603 33.3330
ML039 SNG-M CTRP1 0.2603 33.3330
ML039 BL-70 CTRP1 0.2603 33.3330
ML039 HT CTRP1 0.2603 33.3330
ML039 KU812 CTRP1 0.2603 33.3330
ML039 MC116 CTRP1 0.2603 33.3330
ML039 P3HR-1 CTRP1 0.2603 33.3330
ML039 VMRC-RCW CTRP1 0.2603 33.3330
ML039 C2BBE1 CTRP1 0.2603 33.3330
ML039 COLO205 CTRP1 0.2603 33.3330
ML039 DLD-1 CTRP1 0.2603 33.3330
ML039 GP2D CTRP1 0.2603 33.3330
ML039 LS411N CTRP1 0.2603 33.3330
ML039 LS513 CTRP1 0.2603 33.3330
ML039 SK-CO-1 CTRP1 0.2603 33.3330
ML039 SNU-C2A CTRP1 0.2603 33.3330
ML039 SW403 CTRP1 0.2603 33.3330
ML039 SW48 CTRP1 0.2603 33.3330
ML039 JHH-6 CTRP1 0.2603 33.3330
ML039 SNU-449 CTRP1 0.2603 33.3330
ML039 A-549 CTRP1 0.2603 33.3330
ML039 BEN CTRP1 0.2603 33.3330
ML039 CALU-3 CTRP1 0.2603 33.3330
ML039 CALU-6 CTRP1 0.2603 33.3330
ML039 CHAGO-K-1 CTRP1 0.2603 33.3330
ML039 COLO668 CTRP1 0.2603 33.3330
ML039 COR-L279 CTRP1 0.2603 33.3330
ML039 COR-L88 CTRP1 0.2603 33.3330
ML039 DMS273 CTRP1 0.2603 33.3330
ML039 DV-90 CTRP1 0.2603 33.3330
ML039 EBC-1 CTRP1 0.2603 33.3330
ML039 EPLC-272H CTRP1 0.2603 33.3330
ML039 HARA[HUMANSQUAMOUSCELLLUNGCARCINOMA] CTRP1 0.2603 33.3330
ML039 HCC33 CTRP1 0.2603 33.3330
ML039 HCC44 CTRP1 0.2603 33.3330
ML039 HCC78 CTRP1 0.2603 33.3330
ML039 KNS-62 CTRP1 0.2603 33.3330
ML039 LC-1-SQ-SF CTRP1 0.2603 33.3330
ML039 LCLC-103H CTRP1 0.2603 33.3330
ML039 LCLC-97TM1 CTRP1 0.2603 33.3330
ML039 LU-65 CTRP1 0.2603 33.3330
ML039 LU-99 CTRP1 0.2603 33.3330
ML039 LXF289 CTRP1 0.2603 33.3330
ML039 NCI-H1048 CTRP1 0.2603 33.3330
ML039 NCI-H1299 CTRP1 0.2603 33.3330
ML039 NCI-H1355 CTRP1 0.2603 33.3330
ML039 NCI-H1373 CTRP1 0.2603 33.3330
ML039 NCI-H1435 CTRP1 0.2603 33.3330
ML039 NCI-H1437 CTRP1 0.2603 33.3330
ML039 NCI-H1568 CTRP1 0.2603 33.3330
ML039 NCI-H1573 CTRP1 0.2603 33.3330
ML039 NCI-H1666 CTRP1 0.2603 33.3330
ML039 NCI-H1792 CTRP1 0.2603 33.3330
ML039 NCI-H1793 CTRP1 0.2603 33.3330
ML039 NCI-H1915 CTRP1 0.2603 33.3330
ML039 NCI-H1930 CTRP1 0.2603 33.3330
ML039 NCI-H1944 CTRP1 0.2603 33.3330
ML039 NCI-H1975 CTRP1 0.2603 33.3330
ML039 NCI-H2009 CTRP1 0.2603 33.3330
ML039 NCI-H2029 CTRP1 0.2603 33.3330
ML039 NCI-H2126 CTRP1 0.2603 33.3330
ML039 NCI-H2286 CTRP1 0.2603 33.3330
ML039 NCI-H23 CTRP1 0.2603 33.3330
ML039 NCI-H2405 CTRP1 0.2603 33.3330
ML039 NCI-H358 CTRP1 0.2603 33.3330
ML039 NCI-H522 CTRP1 0.2603 33.3330
ML039 NCI-H650 CTRP1 0.2603 33.3330
ML039 NCI-H661 CTRP1 0.2603 33.3330
ML039 NCI-H727 CTRP1 0.2603 33.3330
ML039 NCI-H810 CTRP1 0.2603 33.3330
ML039 NCI-H82 CTRP1 0.2603 33.3330
ML039 RERF-LC-KJ CTRP1 0.2603 33.3330
ML039 SHP-77 CTRP1 0.2603 33.3330
ML039 VMRC-LCD CTRP1 0.2603 33.3330
ML039 KYSE-140 CTRP1 0.2603 33.3330
ML039 KYSE-410 CTRP1 0.2603 33.3330
ML039 KYSE-450 CTRP1 0.2603 33.3330
ML039 COV318 CTRP1 0.2603 33.3330
ML039 EFO-21 CTRP1 0.2603 33.3330
ML039 HEYA8 CTRP1 0.2603 33.3330
ML039 JHOS-4 CTRP1 0.2603 33.3330
ML039 OVMANA CTRP1 0.2603 33.3330
ML039 SK-OV-3 CTRP1 0.2603 33.3330
ML039 CAPAN-2 CTRP1 0.2603 33.3330
ML039 CFPAC-1 CTRP1 0.2603 33.3330
ML039 HPAC CTRP1 0.2603 33.3330
ML039 HUP-T4 CTRP1 0.2603 33.3330
ML039 KP-3 CTRP1 0.2603 33.3330
ML039 PANC03.27 CTRP1 0.2603 33.3330
ML039 PANC10.05 CTRP1 0.2603 33.3330
ML039 PATU8902 CTRP1 0.2603 33.3330
ML039 QGP-1 CTRP1 0.2603 33.3330
ML039 SUIT-2 CTRP1 0.2603 33.3330
ML039 MSTO-211H CTRP1 0.2603 33.3330
ML039 NCI-H2052 CTRP1 0.2603 33.3330
ML039 NCI-H28 CTRP1 0.2603 33.3330
ML039 MIAPACA-3 CTRP1 0.2603 33.3330
ML039 COLO741 CTRP1 0.2603 33.3330
ML039 G-361 CTRP1 0.2603 33.3330
ML039 HS852.T CTRP1 0.2603 33.3330
ML039 HS936.T CTRP1 0.2603 33.3330
ML039 HS944.T CTRP1 0.2603 33.3330
ML039 G-401 CTRP1 0.2603 33.3330
ML039 FU97 CTRP1 0.2603 33.3330
ML039 KE-97 CTRP1 0.2603 33.3330
ML039 MKN7 CTRP1 0.2603 33.3330
ML039 MKN74 CTRP1 0.2603 33.3330
ML039 NUGC-4 CTRP1 0.2603 33.3330
ML039 SH-10-TC CTRP1 0.2603 33.3330
ML039 HSC-2 CTRP1 0.2603 33.3330
ML039 5637 CTRP1 0.2603 33.3330
ML039 HT-1376 CTRP1 0.2603 33.3330
ML039 KMBC-2 CTRP1 0.2603 33.3330
ML039 RT-4 CTRP1 0.2603 33.3330
ML039 UM-UC-3 CTRP1 0.2603 33.3330

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Cell lines with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Cell lines with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Cell lines with highest and lowest AUC

Associated Genes (Mutation)

Genes with the largest and lowest Racksum’s effect sizes, calculated by comparing IC50 between the mutant and wide type cell lines using cell lines from pancan data.

Associated Genes (Gene Expression)

Genes with the highest and lowest Spearman correlations, calculated by comparing gene expression and IC50 across cell lines from pancan data.