Drug : Ly-2365109

CTRP1 Name : LY-2365109

Dataset : All
Synonyms :
Targets : SLC6A9
Pathways : inhibitor of glycine transporter 1 (GlyT1)

Information Cards

Click to show/hide information cards below or download all drug response information.

           
     

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including drug name, cell line name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Drug name Cellosaurus ID Original Dataset(s) Min Dose Max Dose Dose-response
LY-2365109 GAMG CTRP1 0.2603 33.3330
LY-2365109 SF295 CTRP1 0.2603 33.3330
LY-2365109 HEC-108 CTRP1 0.2603 33.3330
LY-2365109 HEC-251 CTRP1 0.2603 33.3330
LY-2365109 HEC-265 CTRP1 0.2603 33.3330
LY-2365109 HEC-59 CTRP1 0.2603 33.3330
LY-2365109 HEC-6 CTRP1 0.2603 33.3330
LY-2365109 ISHIKAWA(HERAKLIO)02ER- CTRP1 0.2603 33.3330
LY-2365109 KLE CTRP1 0.2603 33.3330
LY-2365109 MFE-319 CTRP1 0.2603 33.3330
LY-2365109 SNG-M CTRP1 0.2603 33.3330
LY-2365109 BL-70 CTRP1 0.2603 33.3330
LY-2365109 HT CTRP1 0.2603 33.3330
LY-2365109 KU812 CTRP1 0.2603 33.3330
LY-2365109 MC116 CTRP1 0.2603 33.3330
LY-2365109 P3HR-1 CTRP1 0.2603 33.3330
LY-2365109 VMRC-RCW CTRP1 0.2603 33.3330
LY-2365109 C2BBE1 CTRP1 0.2603 33.3330
LY-2365109 COLO205 CTRP1 0.2603 33.3330
LY-2365109 DLD-1 CTRP1 0.2603 33.3330
LY-2365109 GP2D CTRP1 0.2603 33.3330
LY-2365109 LS411N CTRP1 0.2603 33.3330
LY-2365109 LS513 CTRP1 0.2603 33.3330
LY-2365109 SK-CO-1 CTRP1 0.2603 33.3330
LY-2365109 SNU-C2A CTRP1 0.2603 33.3330
LY-2365109 SW403 CTRP1 0.2603 33.3330
LY-2365109 SW48 CTRP1 0.2603 33.3330
LY-2365109 JHH-6 CTRP1 0.2603 33.3330
LY-2365109 SNU-449 CTRP1 0.2603 33.3330
LY-2365109 A-549 CTRP1 0.2603 33.3330
LY-2365109 BEN CTRP1 0.2603 33.3330
LY-2365109 CALU-3 CTRP1 0.2603 33.3330
LY-2365109 CALU-6 CTRP1 0.2603 33.3330
LY-2365109 CHAGO-K-1 CTRP1 0.2603 33.3330
LY-2365109 COLO668 CTRP1 0.2603 33.3330
LY-2365109 COR-L279 CTRP1 0.2603 33.3330
LY-2365109 COR-L88 CTRP1 0.2603 33.3330
LY-2365109 DMS273 CTRP1 0.2603 33.3330
LY-2365109 DV-90 CTRP1 0.2603 33.3330
LY-2365109 EBC-1 CTRP1 0.2603 33.3330
LY-2365109 EPLC-272H CTRP1 0.2603 33.3330
LY-2365109 HARA[HUMANSQUAMOUSCELLLUNGCARCINOMA] CTRP1 0.2603 33.3330
LY-2365109 HCC33 CTRP1 0.2603 33.3330
LY-2365109 HCC44 CTRP1 0.2603 33.3330
LY-2365109 HCC78 CTRP1 0.2603 33.3330
LY-2365109 KNS-62 CTRP1 0.2603 33.3330
LY-2365109 LC-1-SQ-SF CTRP1 0.2603 33.3330
LY-2365109 LCLC-103H CTRP1 0.2603 33.3330
LY-2365109 LCLC-97TM1 CTRP1 0.2603 33.3330
LY-2365109 LU-65 CTRP1 0.2603 33.3330
LY-2365109 LU-99 CTRP1 0.2603 33.3330
LY-2365109 LXF289 CTRP1 0.2603 33.3330
LY-2365109 NCI-H1048 CTRP1 0.2603 33.3330
LY-2365109 NCI-H1299 CTRP1 0.2603 33.3330
LY-2365109 NCI-H1355 CTRP1 0.2603 33.3330
LY-2365109 NCI-H1373 CTRP1 0.2603 33.3330
LY-2365109 NCI-H1435 CTRP1 0.2603 33.3330
LY-2365109 NCI-H1437 CTRP1 0.2603 33.3330
LY-2365109 NCI-H1568 CTRP1 0.2603 33.3330
LY-2365109 NCI-H1573 CTRP1 0.2603 33.3330
LY-2365109 NCI-H1666 CTRP1 0.2603 33.3330
LY-2365109 NCI-H1792 CTRP1 0.2603 33.3330
LY-2365109 NCI-H1793 CTRP1 0.2603 33.3330
LY-2365109 NCI-H1915 CTRP1 0.2603 33.3330
LY-2365109 NCI-H1930 CTRP1 0.2603 33.3330
LY-2365109 NCI-H1944 CTRP1 0.2603 33.3330
LY-2365109 NCI-H1975 CTRP1 0.2603 33.3330
LY-2365109 NCI-H2009 CTRP1 0.2603 33.3330
LY-2365109 NCI-H2029 CTRP1 0.2603 33.3330
LY-2365109 NCI-H2126 CTRP1 0.2603 33.3330
LY-2365109 NCI-H2286 CTRP1 0.2603 33.3330
LY-2365109 NCI-H23 CTRP1 0.2603 33.3330
LY-2365109 NCI-H2405 CTRP1 0.2603 33.3330
LY-2365109 NCI-H358 CTRP1 0.2603 33.3330
LY-2365109 NCI-H522 CTRP1 0.2603 33.3330
LY-2365109 NCI-H650 CTRP1 0.2603 33.3330
LY-2365109 NCI-H661 CTRP1 0.2603 33.3330
LY-2365109 NCI-H727 CTRP1 0.2603 33.3330
LY-2365109 NCI-H810 CTRP1 0.2603 33.3330
LY-2365109 NCI-H82 CTRP1 0.2603 33.3330
LY-2365109 RERF-LC-KJ CTRP1 0.2603 33.3330
LY-2365109 SHP-77 CTRP1 0.2603 33.3330
LY-2365109 VMRC-LCD CTRP1 0.2603 33.3330
LY-2365109 KYSE-140 CTRP1 0.2603 33.3330
LY-2365109 KYSE-410 CTRP1 0.2603 33.3330
LY-2365109 KYSE-450 CTRP1 0.2603 33.3330
LY-2365109 COV318 CTRP1 0.2603 33.3330
LY-2365109 EFO-21 CTRP1 0.2603 33.3330
LY-2365109 HEYA8 CTRP1 0.2603 33.3330
LY-2365109 JHOS-4 CTRP1 0.2603 33.3330
LY-2365109 OVMANA CTRP1 0.2603 33.3330
LY-2365109 SK-OV-3 CTRP1 0.2603 33.3330
LY-2365109 CAPAN-2 CTRP1 0.2603 33.3330
LY-2365109 CFPAC-1 CTRP1 0.2603 33.3330
LY-2365109 HPAC CTRP1 0.2603 33.3330
LY-2365109 HUP-T4 CTRP1 0.2603 33.3330
LY-2365109 KP-3 CTRP1 0.2603 33.3330
LY-2365109 PANC03.27 CTRP1 0.2603 33.3330
LY-2365109 PANC10.05 CTRP1 0.2603 33.3330
LY-2365109 PATU8902 CTRP1 0.2603 33.3330
LY-2365109 QGP-1 CTRP1 0.2603 33.3330
LY-2365109 SUIT-2 CTRP1 0.2603 33.3330
LY-2365109 MSTO-211H CTRP1 0.2603 33.3330
LY-2365109 NCI-H2052 CTRP1 0.2603 33.3330
LY-2365109 NCI-H28 CTRP1 0.2603 33.3330
LY-2365109 MIAPACA-3 CTRP1 0.2603 33.3330
LY-2365109 COLO741 CTRP1 0.2603 33.3330
LY-2365109 G-361 CTRP1 0.2603 33.3330
LY-2365109 HS852.T CTRP1 0.2603 33.3330
LY-2365109 HS936.T CTRP1 0.2603 33.3330
LY-2365109 HS944.T CTRP1 0.2603 33.3330
LY-2365109 G-401 CTRP1 0.2603 33.3330
LY-2365109 FU97 CTRP1 0.2603 33.3330
LY-2365109 KE-97 CTRP1 0.2603 33.3330
LY-2365109 MKN7 CTRP1 0.2603 33.3330
LY-2365109 MKN74 CTRP1 0.2603 33.3330
LY-2365109 NUGC-4 CTRP1 0.2603 33.3330
LY-2365109 SH-10-TC CTRP1 0.2603 33.3330
LY-2365109 HSC-2 CTRP1 0.2603 33.3330
LY-2365109 5637 CTRP1 0.2603 33.3330
LY-2365109 HT-1376 CTRP1 0.2603 33.3330
LY-2365109 KMBC-2 CTRP1 0.2603 33.3330
LY-2365109 RT-4 CTRP1 0.2603 33.3330
LY-2365109 UM-UC-3 CTRP1 0.2603 33.3330

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Cell lines with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Cell lines with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Cell lines with highest and lowest AUC

Associated Genes (Mutation)

Genes with the largest and lowest Racksum’s effect sizes, calculated by comparing IC50 between the mutant and wide type cell lines using cell lines from pancan data.

Associated Genes (Gene Expression)

Genes with the highest and lowest Spearman correlations, calculated by comparing gene expression and IC50 across cell lines from pancan data.