Drug : Brd2649

CTRP1 Name : BRD2649

Dataset : All
Synonyms :
Targets :
Pathways : product of diversity-oriented synthesis

Information Cards

Click to show/hide information cards below or download all drug response information.

           
     

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including drug name, cell line name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Drug name Cellosaurus ID Original Dataset(s) Min Dose Max Dose Dose-response
BRD2649 GAMG CTRP1 0.2603 33.3330
BRD2649 SF295 CTRP1 0.2603 33.3330
BRD2649 HEC-108 CTRP1 0.2603 33.3330
BRD2649 HEC-251 CTRP1 0.2603 33.3330
BRD2649 HEC-265 CTRP1 0.2603 33.3330
BRD2649 HEC-59 CTRP1 0.2603 33.3330
BRD2649 HEC-6 CTRP1 0.2603 33.3330
BRD2649 ISHIKAWA(HERAKLIO)02ER- CTRP1 0.2603 33.3330
BRD2649 KLE CTRP1 0.2603 33.3330
BRD2649 MFE-319 CTRP1 0.2603 33.3330
BRD2649 SNG-M CTRP1 0.2603 33.3330
BRD2649 BL-70 CTRP1 0.2603 33.3330
BRD2649 HT CTRP1 0.2603 33.3330
BRD2649 KU812 CTRP1 0.2603 33.3330
BRD2649 MC116 CTRP1 0.2603 33.3330
BRD2649 P3HR-1 CTRP1 0.2603 33.3330
BRD2649 VMRC-RCW CTRP1 0.2603 33.3330
BRD2649 SNU-C2A CTRP1 0.2603 33.3330
BRD2649 SW403 CTRP1 0.2603 33.3330
BRD2649 JHH-6 CTRP1 0.2603 33.3330
BRD2649 SNU-449 CTRP1 0.2603 33.3330
BRD2649 A-549 CTRP1 0.2603 33.3330
BRD2649 BEN CTRP1 0.2603 33.3330
BRD2649 CALU-3 CTRP1 0.2603 33.3330
BRD2649 CALU-6 CTRP1 0.2603 33.3330
BRD2649 CHAGO-K-1 CTRP1 0.2603 33.3330
BRD2649 COLO668 CTRP1 0.2603 33.3330
BRD2649 COR-L279 CTRP1 0.2603 33.3330
BRD2649 COR-L88 CTRP1 0.2603 33.3330
BRD2649 DMS273 CTRP1 0.2603 33.3330
BRD2649 DV-90 CTRP1 0.2603 33.3330
BRD2649 EPLC-272H CTRP1 0.2603 33.3330
BRD2649 HARA[HUMANSQUAMOUSCELLLUNGCARCINOMA] CTRP1 0.2603 33.3330
BRD2649 HCC33 CTRP1 0.2603 33.3330
BRD2649 HCC44 CTRP1 0.2603 33.3330
BRD2649 KNS-62 CTRP1 0.2603 33.3330
BRD2649 LC-1-SQ-SF CTRP1 0.2603 33.3330
BRD2649 LCLC-103H CTRP1 0.2603 33.3330
BRD2649 LCLC-97TM1 CTRP1 0.2603 33.3330
BRD2649 LU-65 CTRP1 0.2603 33.3330
BRD2649 LXF289 CTRP1 0.2603 33.3330
BRD2649 NCI-H1048 CTRP1 0.2603 33.3330
BRD2649 NCI-H1299 CTRP1 0.2603 33.3330
BRD2649 NCI-H1355 CTRP1 0.2603 33.3330
BRD2649 NCI-H1435 CTRP1 0.2603 33.3330
BRD2649 NCI-H1437 CTRP1 0.2603 33.3330
BRD2649 NCI-H1568 CTRP1 0.2603 33.3330
BRD2649 NCI-H1573 CTRP1 0.2603 33.3330
BRD2649 NCI-H1666 CTRP1 0.2603 33.3330
BRD2649 NCI-H1792 CTRP1 0.2603 33.3330
BRD2649 NCI-H1915 CTRP1 0.2603 33.3330
BRD2649 NCI-H1930 CTRP1 0.2603 33.3330
BRD2649 NCI-H1944 CTRP1 0.2603 33.3330
BRD2649 NCI-H1975 CTRP1 0.2603 33.3330
BRD2649 NCI-H2009 CTRP1 0.2603 33.3330
BRD2649 NCI-H2029 CTRP1 0.2603 33.3330
BRD2649 NCI-H2126 CTRP1 0.2603 33.3330
BRD2649 NCI-H2286 CTRP1 0.2603 33.3330
BRD2649 NCI-H23 CTRP1 0.2603 33.3330
BRD2649 NCI-H2405 CTRP1 0.2603 33.3330
BRD2649 NCI-H650 CTRP1 0.2603 33.3330
BRD2649 NCI-H661 CTRP1 0.2603 33.3330
BRD2649 NCI-H727 CTRP1 0.2603 33.3330
BRD2649 NCI-H810 CTRP1 0.2603 33.3330
BRD2649 NCI-H82 CTRP1 0.2603 33.3330
BRD2649 RERF-LC-KJ CTRP1 0.2603 33.3330
BRD2649 SHP-77 CTRP1 0.2603 33.3330
BRD2649 VMRC-LCD CTRP1 0.2603 33.3330
BRD2649 KYSE-140 CTRP1 0.2603 33.3330
BRD2649 KYSE-410 CTRP1 0.2603 33.3330
BRD2649 KYSE-450 CTRP1 0.2603 33.3330
BRD2649 COV318 CTRP1 0.2603 33.3330
BRD2649 EFO-21 CTRP1 0.2603 33.3330
BRD2649 HEYA8 CTRP1 0.2603 33.3330
BRD2649 JHOS-4 CTRP1 0.2603 33.3330
BRD2649 OVMANA CTRP1 0.2603 33.3330
BRD2649 SK-OV-3 CTRP1 0.2603 33.3330
BRD2649 CAPAN-2 CTRP1 0.2603 33.3330
BRD2649 HUP-T4 CTRP1 0.2603 33.3330
BRD2649 KP-3 CTRP1 0.2603 33.3330
BRD2649 PANC03.27 CTRP1 0.2603 33.3330
BRD2649 PATU8902 CTRP1 0.2603 33.3330
BRD2649 QGP-1 CTRP1 0.2603 33.3330
BRD2649 SUIT-2 CTRP1 0.2603 33.3330
BRD2649 MSTO-211H CTRP1 0.2603 33.3330
BRD2649 NCI-H2052 CTRP1 0.2603 33.3330
BRD2649 NCI-H28 CTRP1 0.2603 33.3330
BRD2649 MIAPACA-3 CTRP1 0.2603 33.3330
BRD2649 G-361 CTRP1 0.2603 33.3330
BRD2649 HS852.T CTRP1 0.2603 33.3330
BRD2649 HS936.T CTRP1 0.2603 33.3330
BRD2649 HS944.T CTRP1 0.2603 33.3330
BRD2649 G-401 CTRP1 0.2603 33.3330
BRD2649 FU97 CTRP1 0.2603 33.3330
BRD2649 KE-97 CTRP1 0.2603 33.3330
BRD2649 MKN7 CTRP1 0.2603 33.3330
BRD2649 MKN74 CTRP1 0.2603 33.3330
BRD2649 NUGC-4 CTRP1 0.2603 33.3330
BRD2649 SH-10-TC CTRP1 0.2603 33.3330
BRD2649 HSC-2 CTRP1 0.2603 33.3330
BRD2649 5637 CTRP1 0.2603 33.3330
BRD2649 HT-1376 CTRP1 0.2603 33.3330
BRD2649 KMBC-2 CTRP1 0.2603 33.3330
BRD2649 RT-4 CTRP1 0.2603 33.3330
BRD2649 UM-UC-3 CTRP1 0.2603 33.3330

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Cell lines with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Cell lines with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Cell lines with highest and lowest AUC

Associated Genes (Mutation)

Genes with the largest and lowest Racksum’s effect sizes, calculated by comparing IC50 between the mutant and wide type cell lines using cell lines from pancan data.

Associated Genes (Gene Expression)

Genes with the highest and lowest Spearman correlations, calculated by comparing gene expression and IC50 across cell lines from pancan data.