Drug : 6-Nbdg

CTRP1 Name : 6-NBDG

Dataset : All
Synonyms :
Targets : HK1;HK2
Pathways : inhibitor of hexokinase

Information Cards

Click to show/hide information cards below or download all drug response information.

           
     

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including drug name, cell line name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Drug name Cellosaurus ID Original Dataset(s) Min Dose Max Dose Dose-response
6-NBDG GAMG CTRP1 0.2603 33.3330
6-NBDG SF295 CTRP1 0.2603 33.3330
6-NBDG HEC-108 CTRP1 0.2603 33.3330
6-NBDG HEC-251 CTRP1 0.2603 33.3330
6-NBDG HEC-265 CTRP1 0.2603 33.3330
6-NBDG HEC-59 CTRP1 0.2603 33.3330
6-NBDG HEC-6 CTRP1 0.2603 33.3330
6-NBDG ISHIKAWA(HERAKLIO)02ER- CTRP1 0.2603 33.3330
6-NBDG KLE CTRP1 0.2603 33.3330
6-NBDG MFE-319 CTRP1 0.2603 33.3330
6-NBDG SNG-M CTRP1 0.2603 33.3330
6-NBDG BL-70 CTRP1 0.2603 33.3330
6-NBDG HT CTRP1 0.2603 33.3330
6-NBDG KU812 CTRP1 0.2603 33.3330
6-NBDG MC116 CTRP1 0.2603 33.3330
6-NBDG P3HR-1 CTRP1 0.2603 33.3330
6-NBDG VMRC-RCW CTRP1 0.2603 33.3330
6-NBDG C2BBE1 CTRP1 0.2603 33.3330
6-NBDG COLO205 CTRP1 0.2603 33.3330
6-NBDG DLD-1 CTRP1 0.2603 33.3330
6-NBDG GP2D CTRP1 0.2603 33.3330
6-NBDG LS411N CTRP1 0.2603 33.3330
6-NBDG LS513 CTRP1 0.2603 33.3330
6-NBDG SK-CO-1 CTRP1 0.2603 33.3330
6-NBDG SNU-C2A CTRP1 0.2603 33.3330
6-NBDG SW403 CTRP1 0.2603 33.3330
6-NBDG SW48 CTRP1 0.2603 33.3330
6-NBDG JHH-6 CTRP1 0.2603 33.3330
6-NBDG SNU-449 CTRP1 0.2603 33.3330
6-NBDG A-549 CTRP1 0.2603 33.3330
6-NBDG BEN CTRP1 0.2603 33.3330
6-NBDG CALU-3 CTRP1 0.2603 33.3330
6-NBDG CALU-6 CTRP1 0.2603 33.3330
6-NBDG CHAGO-K-1 CTRP1 0.2603 33.3330
6-NBDG COLO668 CTRP1 0.2603 33.3330
6-NBDG COR-L279 CTRP1 0.2603 33.3330
6-NBDG COR-L88 CTRP1 0.2603 33.3330
6-NBDG DMS273 CTRP1 0.2603 33.3330
6-NBDG DV-90 CTRP1 0.2603 33.3330
6-NBDG EBC-1 CTRP1 0.2603 33.3330
6-NBDG EPLC-272H CTRP1 0.2603 33.3330
6-NBDG HARA[HUMANSQUAMOUSCELLLUNGCARCINOMA] CTRP1 0.2603 33.3330
6-NBDG HCC33 CTRP1 0.2603 33.3330
6-NBDG HCC44 CTRP1 0.2603 33.3330
6-NBDG HCC78 CTRP1 0.2603 33.3330
6-NBDG KNS-62 CTRP1 0.2603 33.3330
6-NBDG LC-1-SQ-SF CTRP1 0.2603 33.3330
6-NBDG LCLC-103H CTRP1 0.2603 33.3330
6-NBDG LCLC-97TM1 CTRP1 0.2603 33.3330
6-NBDG LU-65 CTRP1 0.2603 33.3330
6-NBDG LU-99 CTRP1 0.2603 33.3330
6-NBDG LXF289 CTRP1 0.2603 33.3330
6-NBDG NCI-H1048 CTRP1 0.2603 33.3330
6-NBDG NCI-H1299 CTRP1 0.2603 33.3330
6-NBDG NCI-H1355 CTRP1 0.2603 33.3330
6-NBDG NCI-H1373 CTRP1 0.2603 33.3330
6-NBDG NCI-H1435 CTRP1 0.2603 33.3330
6-NBDG NCI-H1437 CTRP1 0.2603 33.3330
6-NBDG NCI-H1568 CTRP1 0.2603 33.3330
6-NBDG NCI-H1573 CTRP1 0.2603 33.3330
6-NBDG NCI-H1666 CTRP1 0.2603 33.3330
6-NBDG NCI-H1792 CTRP1 0.2603 33.3330
6-NBDG NCI-H1793 CTRP1 0.2603 33.3330
6-NBDG NCI-H1915 CTRP1 0.2603 33.3330
6-NBDG NCI-H1930 CTRP1 0.2603 33.3330
6-NBDG NCI-H1944 CTRP1 0.2603 33.3330
6-NBDG NCI-H1975 CTRP1 0.2603 33.3330
6-NBDG NCI-H2009 CTRP1 0.2603 33.3330
6-NBDG NCI-H2029 CTRP1 0.2603 33.3330
6-NBDG NCI-H2126 CTRP1 0.2603 33.3330
6-NBDG NCI-H2286 CTRP1 0.2603 33.3330
6-NBDG NCI-H23 CTRP1 0.2603 33.3330
6-NBDG NCI-H2405 CTRP1 0.2603 33.3330
6-NBDG NCI-H358 CTRP1 0.2603 33.3330
6-NBDG NCI-H522 CTRP1 0.2603 33.3330
6-NBDG NCI-H650 CTRP1 0.2603 33.3330
6-NBDG NCI-H661 CTRP1 0.2603 33.3330
6-NBDG NCI-H727 CTRP1 0.2603 33.3330
6-NBDG NCI-H810 CTRP1 0.2603 33.3330
6-NBDG NCI-H82 CTRP1 0.2603 33.3330
6-NBDG RERF-LC-KJ CTRP1 0.2603 33.3330
6-NBDG SHP-77 CTRP1 0.2603 33.3330
6-NBDG VMRC-LCD CTRP1 0.2603 33.3330
6-NBDG KYSE-140 CTRP1 0.2603 33.3330
6-NBDG KYSE-410 CTRP1 0.2603 33.3330
6-NBDG KYSE-450 CTRP1 0.2603 33.3330
6-NBDG COV318 CTRP1 0.2603 33.3330
6-NBDG EFO-21 CTRP1 0.2603 33.3330
6-NBDG HEYA8 CTRP1 0.2603 33.3330
6-NBDG JHOS-4 CTRP1 0.2603 33.3330
6-NBDG OVMANA CTRP1 0.2603 33.3330
6-NBDG SK-OV-3 CTRP1 0.2603 33.3330
6-NBDG CAPAN-2 CTRP1 0.2603 33.3330
6-NBDG CFPAC-1 CTRP1 0.2603 33.3330
6-NBDG HPAC CTRP1 0.2603 33.3330
6-NBDG HUP-T4 CTRP1 0.2603 33.3330
6-NBDG KP-3 CTRP1 0.2603 33.3330
6-NBDG PANC03.27 CTRP1 0.2603 33.3330
6-NBDG PANC10.05 CTRP1 0.2603 33.3330
6-NBDG PATU8902 CTRP1 0.2603 33.3330
6-NBDG QGP-1 CTRP1 0.2603 33.3330
6-NBDG SUIT-2 CTRP1 0.2603 33.3330
6-NBDG MSTO-211H CTRP1 0.2603 33.3330
6-NBDG NCI-H2052 CTRP1 0.2603 33.3330
6-NBDG NCI-H28 CTRP1 0.2603 33.3330
6-NBDG MIAPACA-3 CTRP1 0.2603 33.3330
6-NBDG COLO741 CTRP1 0.2603 33.3330
6-NBDG G-361 CTRP1 0.2603 33.3330
6-NBDG HS852.T CTRP1 0.2603 33.3330
6-NBDG HS936.T CTRP1 0.2603 33.3330
6-NBDG HS944.T CTRP1 0.2603 33.3330
6-NBDG G-401 CTRP1 0.2603 33.3330
6-NBDG FU97 CTRP1 0.2603 33.3330
6-NBDG KE-97 CTRP1 0.2603 33.3330
6-NBDG MKN7 CTRP1 0.2603 33.3330
6-NBDG MKN74 CTRP1 0.2603 33.3330
6-NBDG NUGC-4 CTRP1 0.2603 33.3330
6-NBDG SH-10-TC CTRP1 0.2603 33.3330
6-NBDG HSC-2 CTRP1 0.2603 33.3330
6-NBDG 5637 CTRP1 0.2603 33.3330
6-NBDG HT-1376 CTRP1 0.2603 33.3330
6-NBDG KMBC-2 CTRP1 0.2603 33.3330
6-NBDG RT-4 CTRP1 0.2603 33.3330
6-NBDG UM-UC-3 CTRP1 0.2603 33.3330

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Cell lines with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Cell lines with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Cell lines with highest and lowest AUC

Associated Genes (Mutation)

Genes with the largest and lowest Racksum’s effect sizes, calculated by comparing IC50 between the mutant and wide type cell lines using cell lines from pancan data.

Associated Genes (Gene Expression)

Genes with the highest and lowest Spearman correlations, calculated by comparing gene expression and IC50 across cell lines from pancan data.