Drug : 5-Benzyl-9-Tert-Butyl-Paullone
CTRP1 Name
: 5-benzyl-9-tert-butyl-paullone
Dataset : All
Synonyms :
Targets : MDH2
Pathways : inhibitor of mitochondrial malate dehydrogenase
Information Cards
Click to show/hide information cards below or download all drug response information.
Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.
Experimental information
Experimental information from All dataset, including drug name, cell line name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.
| Drug name | Cellosaurus ID | Original Dataset(s) | Min Dose | Max Dose | Dose-response |
|---|---|---|---|---|---|
| 5-benzyl-9-tert-butyl-paullone | GAMG | CTRP1 | 0.2603 | 33.3330 |
|
| 5-benzyl-9-tert-butyl-paullone | SF295 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | HEC-108 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | HEC-251 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | HEC-265 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | HEC-59 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | HEC-6 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | ISHIKAWA(HERAKLIO)02ER- | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | KLE | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | MFE-319 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | SNG-M | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | BL-70 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | HT | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | KU812 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | MC116 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | P3HR-1 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | VMRC-RCW | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | C2BBE1 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | COLO205 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | DLD-1 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | GP2D | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | LS411N | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | LS513 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | SK-CO-1 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | SNU-C2A | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | SW403 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | SW48 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | JHH-6 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | SNU-449 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | A-549 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | BEN | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | CALU-3 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | CALU-6 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | CHAGO-K-1 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | COLO668 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | COR-L279 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | COR-L88 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | DMS273 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | DV-90 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | EBC-1 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | EPLC-272H | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | HARA[HUMANSQUAMOUSCELLLUNGCARCINOMA] | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | HCC33 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | HCC44 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | HCC78 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | KNS-62 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | LC-1-SQ-SF | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | LCLC-103H | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | LCLC-97TM1 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | LU-65 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | LU-99 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | LXF289 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | NCI-H1048 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | NCI-H1299 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | NCI-H1355 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | NCI-H1373 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | NCI-H1435 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | NCI-H1437 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | NCI-H1568 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | NCI-H1573 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | NCI-H1666 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | NCI-H1792 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | NCI-H1793 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | NCI-H1915 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | NCI-H1930 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | NCI-H1944 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | NCI-H1975 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | NCI-H2009 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | NCI-H2029 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | NCI-H2126 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | NCI-H2286 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | NCI-H23 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | NCI-H2405 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | NCI-H358 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | NCI-H522 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | NCI-H650 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | NCI-H661 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | NCI-H727 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | NCI-H810 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | NCI-H82 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | RERF-LC-KJ | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | SHP-77 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | VMRC-LCD | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | KYSE-140 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | KYSE-410 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | KYSE-450 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | COV318 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | EFO-21 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | HEYA8 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | JHOS-4 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | OVMANA | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | SK-OV-3 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | CAPAN-2 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | CFPAC-1 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | HPAC | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | HUP-T4 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | KP-3 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | PANC03.27 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | PANC10.05 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | PATU8902 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | QGP-1 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | SUIT-2 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | MSTO-211H | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | NCI-H2052 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | NCI-H28 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | MIAPACA-3 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | COLO741 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | G-361 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | HS852.T | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | HS936.T | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | HS944.T | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | G-401 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | FU97 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | KE-97 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | MKN7 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | MKN74 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | NUGC-4 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | SH-10-TC | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | HSC-2 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | 5637 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | HT-1376 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | KMBC-2 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | RT-4 | CTRP1 | 0.2603 | 33.3330 |
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| 5-benzyl-9-tert-butyl-paullone | UM-UC-3 | CTRP1 | 0.2603 | 33.3330 |
|
IC50
IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.
Cell lines with highest and lowest IC50
Cell lines with highest and lowest IC50
IC90
IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.
Cell lines with highest and lowest IC90
Cell lines with highest and lowest IC90
AUC
AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.
Cell lines with highest and lowest AUC
Cell lines with highest and lowest AUC
Associated Genes (Mutation)
Genes with the largest and lowest Racksum’s effect sizes, calculated by comparing IC50 between the mutant and wide type cell lines using cell lines from
pancan data.
Associated Genes (Gene Expression)
Genes with the highest and lowest Spearman correlations, calculated by comparing gene expression and IC50 across cell lines from
pancan data.