Cell Line : NCI-H1385

Cellosaurus Index : CVCL_1466
Cellosaurus ID : NCI-H1385

CTRP2 Name : NCIH1385
CCLE Name : NCIH1385_LUNG

Cancer Type : lung
Dataset : All

Drug Response Information

Click to show/hide information cards below or download all drug response information.

           

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

:

Experimental information

Experimental information from All dataset, including cell line name, drug name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Cellosaurus ID Drug Name Original Dataset(s) Min Dose Max Dose Dose-response
NCI-H1385 1S,3R-RSL-3 CTRP2 0.0010 33.0000
NCI-H1385 Afatinib CTRP2 0.0020 66.0000
NCI-H1385 Alisertib CTRP2 0.0020 66.0000
NCI-H1385 alisertib:navitoclax (2:1 mol-mol) CTRP2 0.0015 50.0000
NCI-H1385 AT7867 CTRP2 0.0020 66.0000
NCI-H1385 Axitinib CTRP2 0.0020 66.0000
NCI-H1385 AZD1480 CTRP2 0.0020 66.0000
NCI-H1385 AZD4547 CTRP2 0.0020 66.0000
NCI-H1385 AZD6482 CTRP2 0.0020 66.0000
NCI-H1385 AZD7762 CTRP2 0.0020 66.0000
NCI-H1385 AZD8055 CTRP2 0.0020 66.0000
NCI-H1385 bendamustine CTRP2 0.0020 66.0000
NCI-H1385 birinapant CTRP2 0.0020 66.0000
NCI-H1385 BMS-195614 CTRP2 0.0020 66.0000
NCI-H1385 BRD-A02303741:navitoclax (2:1 mol-mol) CTRP2 0.0015 50.0000
NCI-H1385 BRD-A05715709 CTRP2 0.0020 66.0000
NCI-H1385 BRD-K19103580 CTRP2 0.0020 66.0000
NCI-H1385 BRD-K28456706 CTRP2 0.0020 66.0000
NCI-H1385 BRD-K29313308 CTRP2 0.0020 66.0000
NCI-H1385 BRD-K34222889 CTRP2 0.0017 57.0000
NCI-H1385 BRD-K42260513 CTRP2 0.0020 66.0000
NCI-H1385 BRD-K45681478 CTRP2 0.0020 66.0000
NCI-H1385 BRD-K50799972 CTRP2 0.0020 66.0000
NCI-H1385 BRD-K51490254 CTRP2 0.0020 66.0000
NCI-H1385 BRD-K55116708 CTRP2 0.0020 66.0000
NCI-H1385 BRD-K61166597 CTRP2 0.0020 66.0000
NCI-H1385 BRD-K66453893 CTRP2 0.0020 66.0000
NCI-H1385 BRD-K70511574 CTRP2 0.0020 66.0000
NCI-H1385 BRD-K71781559 CTRP2 0.0020 66.0000
NCI-H1385 BRD-K71935468 CTRP2 0.0025 83.0000
NCI-H1385 BRD-K88742110 CTRP2 0.0020 66.0000
NCI-H1385 BRD-K97651142 CTRP2 0.0020 66.0000
NCI-H1385 BRD1812 CTRP2 0.0020 66.0000
NCI-H1385 BRD8899 CTRP2 0.0010 33.0000
NCI-H1385 BRD9876:MK-1775 (4:1 mol-mol) CTRP2 0.0020 66.0000
NCI-H1385 brefeldin A CTRP2 0.0011 37.0000
NCI-H1385 canertinib CTRP2 0.0020 66.0000
NCI-H1385 carboplatin:UNC0638 (2:1 mol-mol) CTRP2 0.0015 50.0000
NCI-H1385 CAY10594 CTRP2 0.0020 66.0000
NCI-H1385 CAY10618 CTRP2 0.0010 33.0000
NCI-H1385 CCT036477 CTRP2 0.0010 33.0000
NCI-H1385 CD-1530 CTRP2 0.0041 130.0000
NCI-H1385 CD-437 CTRP2 0.0011 37.0000
NCI-H1385 ceranib-2 CTRP2 0.0020 66.0000
NCI-H1385 cerulenin CTRP2 0.0045 150.0000
NCI-H1385 CHEMBL1222381 CTRP2 0.0081 270.0000
NCI-H1385 CHM-1 CTRP2 0.0005 16.0000
NCI-H1385 ciclopirox CTRP2 0.0020 66.0000
NCI-H1385 CR-1-31B CTRP2 0.0010 33.0000
NCI-H1385 Crizotinib CTRP2 0.0020 66.0000
NCI-H1385 curcumin CTRP2 0.0051 170.0000
NCI-H1385 cytochalasin B CTRP2 0.0010 33.0000
NCI-H1385 Dasatinib CTRP2 0.0020 66.0000
NCI-H1385 DBeQ CTRP2 0.0020 66.0000
NCI-H1385 Decitabine CTRP2 0.0020 66.0000
NCI-H1385 decitabine:carboplatin (1:1 mol-mol) CTRP2 0.0020 66.0000
NCI-H1385 decitabine:navitoclax (2:1 mol-mol) CTRP2 0.0015 50.0000
NCI-H1385 docetaxel:tanespimycin (2:1 mol-mol) CTRP2 0.0015 50.0000
NCI-H1385 Doramapimod CTRP2 0.0020 66.0000
NCI-H1385 Doxorubicin CTRP2 0.0020 66.0000
NCI-H1385 doxorubicin:navitoclax (2:1 mol-mol) CTRP2 0.0015 50.0000
NCI-H1385 Entinostat CTRP2 0.0020 66.0000
NCI-H1385 Erlotinib CTRP2 0.0020 66.0000
NCI-H1385 erlotinib:PLX-4032 (2:1 mol-mol) CTRP2 0.0015 50.0000
NCI-H1385 Etoposide CTRP2 0.0009 28.0000
NCI-H1385 fluvastatin CTRP2 0.0020 66.0000
NCI-H1385 FQI-2 CTRP2 0.0010 33.0000
NCI-H1385 fumonisin B1 CTRP2 0.0150 500.0000
NCI-H1385 GANT-61 CTRP2 0.0020 66.0000
NCI-H1385 Gemcitabine CTRP2 0.0010 33.0000
NCI-H1385 GSK1059615 CTRP2 0.0010 33.0000
NCI-H1385 GSK4112 CTRP2 0.0020 66.0000
NCI-H1385 GSK461364 CTRP2 0.0020 66.0000
NCI-H1385 IC-87114 CTRP2 0.0020 66.0000
NCI-H1385 Idelalisib CTRP2 0.0020 66.0000
NCI-H1385 Imatinib CTRP2 0.0020 66.0000
NCI-H1385 indisulam CTRP2 0.0010 33.0000
NCI-H1385 isoevodiamine CTRP2 0.0010 33.0000
NCI-H1385 isonicotinohydroxamic acid CTRP2 0.0010 33.0000
NCI-H1385 ISOX CTRP2 0.0010 33.0000
NCI-H1385 JQ-1:carboplatin (1:1 mol-mol) CTRP2 0.0020 66.0000
NCI-H1385 JQ-1:MK-0752 (1:1 mol-mol) CTRP2 0.0020 66.0000
NCI-H1385 JQ-1:navitoclax (2:1 mol-mol) CTRP2 0.0015 50.0000
NCI-H1385 JQ1 CTRP2 0.0020 66.0000
NCI-H1385 JW-480 CTRP2 0.0020 66.0000
NCI-H1385 KHS101 CTRP2 0.0020 66.0000
NCI-H1385 Ki8751 CTRP2 0.0020 66.0000
NCI-H1385 KPT185 CTRP2 0.0020 66.0000
NCI-H1385 KU-0063794 CTRP2 0.0020 66.0000
NCI-H1385 KW-2449 CTRP2 0.0020 66.0000
NCI-H1385 KX2-391 CTRP2 0.0020 66.0000
NCI-H1385 L-685458 CTRP2 0.0011 37.0000
NCI-H1385 Lapatinib CTRP2 0.0020 66.0000
NCI-H1385 LBH-589 CTRP2 0.0020 66.0000
NCI-H1385 LE-135 CTRP2 0.0020 66.0000
NCI-H1385 Linifanib CTRP2 0.0020 66.0000
NCI-H1385 LY-2183240 CTRP2 0.0010 33.0000
NCI-H1385 manumycin A CTRP2 0.0009 30.0000
NCI-H1385 marinopyrrole A CTRP2 0.0020 66.0000
NCI-H1385 Merck60 CTRP2 0.0010 33.0000
NCI-H1385 Methotrexate CTRP2 0.0020 66.0000
NCI-H1385 MGCD-265 CTRP2 0.0020 66.0000
NCI-H1385 MI-2 CTRP2 0.0020 66.0000
NCI-H1385 MK-2206 CTRP2 0.0010 33.0000
NCI-H1385 ML320 CTRP2 0.0020 66.0000
NCI-H1385 ML334 diastereomer CTRP2 0.0041 130.0000
NCI-H1385 momelotinib CTRP2 0.0020 66.0000
NCI-H1385 myricetin CTRP2 0.0020 66.0000
NCI-H1385 narciclasine CTRP2 0.0010 33.0000
NCI-H1385 Navitoclax CTRP2 0.0010 33.0000
NCI-H1385 navitoclax:birinapant (1:1 mol-mol) CTRP2 0.0010 33.0000
NCI-H1385 navitoclax:MST-312 (1:1 mol-mol) CTRP2 0.0010 33.0000
NCI-H1385 navitoclax:piperlongumine (1:1 mol-mol) CTRP2 0.0010 33.0000
NCI-H1385 navitoclax:pluripotin (1:1 mol-mol) CTRP2 0.0010 33.0000
NCI-H1385 navitoclax:sorafenib (1:1 mol-mol) CTRP2 0.0015 50.0000
NCI-H1385 necrostatin-1 CTRP2 0.0160 530.0000
NCI-H1385 necrosulfonamide CTRP2 0.0020 66.0000
NCI-H1385 Nelarabine CTRP2 0.0020 66.0000
NCI-H1385 Nilotinib CTRP2 0.0020 66.0000
NCI-H1385 nintedanib CTRP2 0.0020 66.0000
NCI-H1385 NSC30930 CTRP2 0.0020 66.0000
NCI-H1385 NSC632839 CTRP2 0.0010 33.0000
NCI-H1385 NVP-ADW742 CTRP2 0.0020 66.0000
NCI-H1385 Obatoclax Mesylate CTRP2 0.0020 66.0000
NCI-H1385 OSI-027 CTRP2 0.0020 66.0000
NCI-H1385 OSI-930 CTRP2 0.0020 66.0000
NCI-H1385 ouabain CTRP2 0.0081 270.0000
NCI-H1385 Oxaliplatin CTRP2 0.0020 66.0000
NCI-H1385 PAC-1 CTRP2 0.0010 33.0000
NCI-H1385 parbendazole CTRP2 0.0020 66.0000
NCI-H1385 PD 153035 CTRP2 0.0010 33.0000
NCI-H1385 PD318088 CTRP2 0.0020 66.0000
NCI-H1385 PDMP CTRP2 0.0065 210.0000
NCI-H1385 PF-184 CTRP2 0.0020 66.0000
NCI-H1385 PHA-793887 CTRP2 0.0020 66.0000
NCI-H1385 piperlongumine:MST-312 (1:1 mol-mol) CTRP2 0.0010 33.0000
NCI-H1385 pluripotin CTRP2 0.0010 33.0000
NCI-H1385 PLX-4720 CTRP2 0.0010 33.0000
NCI-H1385 PRIMA-1 CTRP2 0.0051 170.0000
NCI-H1385 prochlorperazine CTRP2 0.0020 66.0000
NCI-H1385 pyrazolanthrone CTRP2 0.0020 66.0000
NCI-H1385 Quizartinib CTRP2 0.0020 66.0000
NCI-H1385 RAF265 CTRP2 0.0020 66.0000
NCI-H1385 Rapamycin CTRP2 0.0010 33.0000
NCI-H1385 Repligen 136 CTRP2 0.0020 66.0000
NCI-H1385 rigosertib CTRP2 0.0020 66.0000
NCI-H1385 salermide:PLX-4032 (12:1 mol-mol) CTRP2 0.0066 220.0000
NCI-H1385 SB-431542 CTRP2 0.0020 66.0000
NCI-H1385 SB-525334 CTRP2 0.0020 66.0000
NCI-H1385 SB-743921 CTRP2 0.0010 33.0000
NCI-H1385 SCH-529074 CTRP2 0.0010 33.0000
NCI-H1385 SGX-523 CTRP2 0.0020 66.0000
NCI-H1385 silmitasertib CTRP2 0.0020 66.0000
NCI-H1385 simvastatin CTRP2 0.0010 33.0000
NCI-H1385 SJ-172550 CTRP2 0.0010 33.0000
NCI-H1385 SKI-II CTRP2 0.0041 130.0000
NCI-H1385 SMER-3 CTRP2 0.0020 66.0000
NCI-H1385 SNS-032 CTRP2 0.0020 66.0000
NCI-H1385 Sorafenib CTRP2 0.0020 66.0000
NCI-H1385 spautin-1 CTRP2 0.0020 66.0000
NCI-H1385 SR-II-138A CTRP2 0.0010 33.0000
NCI-H1385 STF-31 CTRP2 0.0020 66.0000
NCI-H1385 SU11274 CTRP2 0.0020 66.0000
NCI-H1385 Sunitinib CTRP2 0.0020 66.0000
NCI-H1385 tacrolimus CTRP2 0.0023 74.0000
NCI-H1385 Tamoxifen CTRP2 0.0030 100.0000
NCI-H1385 Telomerase Inhibitor IX CTRP2 0.0010 33.0000
NCI-H1385 TG-100-115 CTRP2 0.0020 66.0000
NCI-H1385 TGX221 CTRP2 0.0020 66.0000
NCI-H1385 Topotecan CTRP2 0.0020 66.0000
NCI-H1385 Tretinoin CTRP2 0.0041 130.0000
NCI-H1385 TW 37 CTRP2 0.0010 33.0000
NCI-H1385 UNC0321 CTRP2 0.0010 33.0000
NCI-H1385 UNC0638:navitoclax (1:1 mol-mol) CTRP2 0.0010 33.0000
NCI-H1385 Veliparib CTRP2 0.0010 33.0000
NCI-H1385 Vorinostat CTRP2 0.0010 33.0000
NCI-H1385 WP1130 CTRP2 0.0020 66.0000
NCI-H1385 YK-4-279 CTRP2 0.0010 33.0000
NCI-H1385 ZSTK474 CTRP2 0.0020 66.0000

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Drugs with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Drugs with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Drugs with highest and lowest AUC