Drug : Ha-1004

CTRP1 Name : HA-1004

Dataset : All
Synonyms :
Targets : PRKACA;PRKACG
Pathways : inhibitor of PKA and PKG;intracellular calcium antagonist

Information Cards

Click to show/hide information cards below or download all drug response information.

           
     

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including drug name, cell line name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Drug name Cellosaurus ID Original Dataset(s) Min Dose Max Dose Dose-response
HA-1004 GAMG CTRP1 0.4440 56.8160
HA-1004 HEC-108 CTRP1 0.4440 56.8160
HA-1004 HEC-59 CTRP1 0.4440 56.8160
HA-1004 ISHIKAWA(HERAKLIO)02ER- CTRP1 0.4440 56.8160
HA-1004 KLE CTRP1 0.4440 56.8160
HA-1004 SNG-M CTRP1 0.4440 56.8160
HA-1004 BL-70 CTRP1 0.4440 56.8160
HA-1004 JHH-6 CTRP1 0.4440 56.8160
HA-1004 SNU-449 CTRP1 0.4440 56.8160
HA-1004 COLO668 CTRP1 0.4440 56.8160
HA-1004 LXF289 CTRP1 0.4440 56.8160
HA-1004 NCI-H1435 CTRP1 0.4440 56.8160
HA-1004 NCI-H1915 CTRP1 0.4440 56.8160
HA-1004 NCI-H1930 CTRP1 0.4440 56.8160
HA-1004 NCI-H2286 CTRP1 0.4440 56.8160
HA-1004 RERF-LC-KJ CTRP1 0.4440 56.8160
HA-1004 COV318 CTRP1 0.4440 56.8160
HA-1004 JHOS-4 CTRP1 0.4440 56.8160
HA-1004 OVMANA CTRP1 0.4440 56.8160
HA-1004 PATU8902 CTRP1 0.4440 56.8160
HA-1004 MIAPACA-3 CTRP1 0.4440 56.8160
HA-1004 HS852.T CTRP1 0.4440 56.8160
HA-1004 MKN74 CTRP1 0.4440 56.8160

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Cell lines with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Cell lines with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Cell lines with highest and lowest AUC

Associated Genes (Mutation)

Genes with the largest and lowest Racksum’s effect sizes, calculated by comparing IC50 between the mutant and wide type cell lines using cell lines from pancan data.

Associated Genes (Gene Expression)

Genes with the highest and lowest Spearman correlations, calculated by comparing gene expression and IC50 across cell lines from pancan data.