Cell Line : NCI-H128

Cellosaurus Index : CVCL_1460
Cellosaurus ID : NCI-H128

GDSC1 Name : NCI-H128
CCLE Name : NCIH128_LUNG

Cancer Type : lung
Dataset : All

Drug Response Information

Click to show/hide information cards below or download all drug response information.

           

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including cell line name, drug name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Cellosaurus ID Drug Name Original Dataset(s) Min Dose Max Dose Dose-response
NCI-H128 A-443654 GDSC1 0.0040 1.0240
NCI-H128 A-770041 GDSC1 0.0200 5.1200
NCI-H128 AZ628 GDSC1 0.0156 4.0000
NCI-H128 BI-2536 GDSC1 0.0010 0.2560
NCI-H128 BMS-509744 GDSC1 0.0400 10.2400
NCI-H128 BMS-536924 GDSC1 0.0200 5.1200
NCI-H128 Bortezomib GDSC1 0.0001 0.0200
NCI-H128 CGP-082996 GDSC1 0.0200 5.1200
NCI-H128 CGP-60474 GDSC1 0.0010 0.2560
NCI-H128 CMK GDSC1 0.0156 4.0000
NCI-H128 Crizotinib GDSC1 0.0078 2.0000
NCI-H128 Cyclopamine GDSC1 0.0625 16.0000
NCI-H128 Dasatinib GDSC1 0.0050 1.2800
NCI-H128 Entinostat GDSC1 0.0195 5.0000
NCI-H128 Erlotinib GDSC1 0.0078 2.0000
NCI-H128 GNF-2 GDSC1 0.0050 1.2800
NCI-H128 GSK269962A GDSC1 0.0098 2.5000
NCI-H128 GSK319347A GDSC1 0.0195 5.0000
NCI-H128 GW843682X GDSC1 0.0010 0.2560
NCI-H128 Imatinib GDSC1 0.0078 2.0000
NCI-H128 JW-7-52-1 GDSC1 0.0047 1.2000
NCI-H128 Lapatinib GDSC1 0.0078 2.0000
NCI-H128 MG-132 GDSC1 0.0039 1.0000
NCI-H128 NVP-TAE684 GDSC1 0.0078 2.0000
NCI-H128 Paclitaxel GDSC1 0.0004 0.1024
NCI-H128 Parthenolide GDSC1 0.0195 5.0000
NCI-H128 PHA-665752 GDSC1 0.0078 2.0000
NCI-H128 Pyrimethamine GDSC1 0.0781 20.0000
NCI-H128 Rapamycin GDSC1 0.0004 0.1000
NCI-H128 S-Trityl-L-cysteine GDSC1 0.0200 5.1200
NCI-H128 Salubrinal GDSC1 0.0625 16.0000
NCI-H128 Saracatinib GDSC1 0.0078 2.0000
NCI-H128 Seliciclib GDSC1 0.0625 16.0000
NCI-H128 Sorafenib GDSC1 0.0156 4.0000
NCI-H128 Sunitinib GDSC1 0.0312 8.0000
NCI-H128 TGX221 GDSC1 0.0391 10.0000
NCI-H128 Tozasertib GDSC1 0.0078 2.0000
NCI-H128 WH-4-023 GDSC1 0.0200 5.1200
NCI-H128 WZ-1-84 GDSC1 0.0400 10.2400
NCI-H128 XMD8-85 GDSC1 0.0312 8.0000
NCI-H128 Z-LLNle-CHO GDSC1 0.0100 2.5600

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Drugs with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Drugs with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Drugs with highest and lowest AUC