Drug : 6-Methoxyharmalan

CTRP1 Name : 6-methoxyharmalan

Dataset : All
Synonyms :
Targets :
Pathways : natural product;modulates neurochemical receptors

Information Cards

Click to show/hide information cards below or download all drug response information.

           
     

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including drug name, cell line name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Drug name Cellosaurus ID Original Dataset(s) Min Dose Max Dose Dose-response
6-methoxyharmalan GAMG CTRP1 0.2430 31.1140
6-methoxyharmalan HEC-108 CTRP1 0.2430 31.1140
6-methoxyharmalan HEC-59 CTRP1 0.2430 31.1140
6-methoxyharmalan ISHIKAWA(HERAKLIO)02ER- CTRP1 0.2430 31.1140
6-methoxyharmalan KLE CTRP1 0.2430 31.1140
6-methoxyharmalan SNG-M CTRP1 0.2430 31.1140
6-methoxyharmalan BL-70 CTRP1 0.2430 31.1140
6-methoxyharmalan JHH-6 CTRP1 0.2430 31.1140
6-methoxyharmalan SNU-449 CTRP1 0.2430 31.1140
6-methoxyharmalan COLO668 CTRP1 0.2430 31.1140
6-methoxyharmalan LXF289 CTRP1 0.2430 31.1140
6-methoxyharmalan NCI-H1435 CTRP1 0.2430 31.1140
6-methoxyharmalan NCI-H1915 CTRP1 0.2430 31.1140
6-methoxyharmalan NCI-H1930 CTRP1 0.2430 31.1140
6-methoxyharmalan NCI-H2286 CTRP1 0.2430 31.1140
6-methoxyharmalan RERF-LC-KJ CTRP1 0.2430 31.1140
6-methoxyharmalan COV318 CTRP1 0.2430 31.1140
6-methoxyharmalan JHOS-4 CTRP1 0.2430 31.1140
6-methoxyharmalan OVMANA CTRP1 0.2430 31.1140
6-methoxyharmalan PATU8902 CTRP1 0.2430 31.1140
6-methoxyharmalan MIAPACA-3 CTRP1 0.2430 31.1140
6-methoxyharmalan HS852.T CTRP1 0.2430 31.1140
6-methoxyharmalan MKN74 CTRP1 0.2430 31.1140

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Cell lines with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Cell lines with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Cell lines with highest and lowest AUC

Associated Genes (Mutation)

Genes with the largest and lowest Racksum’s effect sizes, calculated by comparing IC50 between the mutant and wide type cell lines using cell lines from pancan data.

Associated Genes (Gene Expression)

Genes with the highest and lowest Spearman correlations, calculated by comparing gene expression and IC50 across cell lines from pancan data.