Cell Line vs Drug : DIFI vs alpha-lipoic acid

Cellosaurus ID : DIFI
Drug Name : alpha-lipoic acid
Dataset : All (GDSC2)

Information Cards

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Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Dose Response Relationship

Each dot indicates drug response at different dosages, and each color represents the original datasets. A pink line is an integrated dose-response curve. Grey lines represent alternative dose-response curves resulting from a Bayesian curve fitting. A horizontal dashed line represents 50% cell inhibitions. A vertical dashed line represents IC50.

−4−20246−0.200.20.40.60.811.2
GDSC2Log2 Concentration (μM)Response

IC50 Distribution

Distribution of drug dosage needed to inhibit the cells by 50%. Dashed lines represent 95% high-density interval (HDI).

8910111213141516
Log2 Concentration (μM)
Drug Sensitivity Scores
IC50 9.1619 log2 Concentration (μM)
IC90 11.5462 log2 Concentration (μM)
AUC 1.2977 %
EC50 6.1001 log2 Concentration (μM)
Einf 0.1123 cell death rate