Cell Line vs Drug : NCI-H835 vs PF-4708671

Cellosaurus ID : NCI-H835
Drug Name : PF-4708671
Dataset : All (GDSC1)

Information Cards

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Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Dose Response Relationship

Each dot indicates drug response at different dosages, and each color represents the original datasets. A pink line is an integrated dose-response curve. Grey lines represent alternative dose-response curves resulting from a Bayesian curve fitting. A horizontal dashed line represents 50% cell inhibitions. A vertical dashed line represents IC50.

IC50 Distribution

Distribution of drug dosage needed to inhibit the cells by 50%. Dashed lines represent 95% high-density interval (HDI).

Drug Sensitivity Scores
IC50 5.6694 log2 Concentration (μM)
IC90 7.6772 log2 Concentration (μM)
AUC 0.8431 %
EC50 2.6542 log2 Concentration (μM)
Einf 0.0712 cell death rate