Cell Line : PL45

Cellosaurus Index : CVCL_3567
Cellosaurus ID : PL45

CCLE Name : PL45_PANCREAS
CTRP2 Name : PL45

Cancer Type : pancreas
Dataset : All

Drug Response Information

Click to show/hide information cards below or download all drug response information.

           

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including cell line name, drug name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Cellosaurus ID Drug Name Original Dataset(s) Min Dose Max Dose Dose-response
PL45 AEW541 CCLE 0.0025 8.0000
PL45 Crizotinib CCLE 0.0025 8.0000
PL45 Erlotinib CCLE 0.0025 8.0000
PL45 Irinotecan CCLE 0.0025 8.0000
PL45 L-685458 CCLE 0.0025 8.0000
PL45 Lapatinib CCLE 0.0025 8.0000
PL45 LBW242 CCLE 0.0025 8.0000
PL45 Nilotinib CCLE 0.0025 8.0000
PL45 Nutlin-3a CCLE 0.0025 8.0000
PL45 NVP-TAE684 CCLE 0.0025 8.0000
PL45 Paclitaxel CCLE 0.0025 8.0000
PL45 Palbociclib CCLE 0.0025 8.0000
PL45 Panobinostat CCLE 0.0025 8.0000
PL45 PD0325901 CCLE 0.0025 8.0000
PL45 PHA-665752 CCLE 0.0025 8.0000
PL45 PLX-4720 CCLE 0.0025 8.0000
PL45 RAF265 CCLE 0.0025 8.0000
PL45 Saracatinib CCLE 0.0025 8.0000
PL45 Selumetinib CCLE 0.0025 8.0000
PL45 Sorafenib CCLE 0.0025 8.0000
PL45 Tanespimycin CCLE 0.0025 8.0000
PL45 TKI258 CCLE 0.0025 8.0000
PL45 Topotecan CCLE 0.0025 8.0000
PL45 ZD-6474 CCLE 0.0025 8.0000

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Drugs with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Drugs with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Drugs with highest and lowest AUC