Cell Line : PK-1

Cellosaurus Index : CVCL_4717
Cellosaurus ID : PK-1

CCLE Name : PK1_PANCREAS

Cancer Type : pancreas
Dataset : All

Drug Response Information

Click to show/hide information cards below or download all drug response information.

           

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including cell line name, drug name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Cellosaurus ID Drug Name Original Dataset(s) Min Dose Max Dose Dose-response
PK-1 AEW541 CCLE 0.0025 8.0000
PK-1 Crizotinib CCLE 0.0025 8.0000
PK-1 Erlotinib CCLE 0.0025 8.0000
PK-1 Irinotecan CCLE 0.0025 8.0000
PK-1 L-685458 CCLE 0.0025 8.0000
PK-1 Lapatinib CCLE 0.0025 8.0000
PK-1 LBW242 CCLE 0.0025 8.0000
PK-1 Nilotinib CCLE 0.0025 8.0000
PK-1 Nutlin-3a CCLE 0.0025 8.0000
PK-1 NVP-TAE684 CCLE 0.0025 8.0000
PK-1 Paclitaxel CCLE 0.0025 8.0000
PK-1 Palbociclib CCLE 0.0025 8.0000
PK-1 Panobinostat CCLE 0.0025 8.0000
PK-1 PD0325901 CCLE 0.0025 8.0000
PK-1 PHA-665752 CCLE 0.0025 8.0000
PK-1 PLX-4720 CCLE 0.0025 8.0000
PK-1 RAF265 CCLE 0.0025 8.0000
PK-1 Saracatinib CCLE 0.0025 8.0000
PK-1 Selumetinib CCLE 0.0025 8.0000
PK-1 Sorafenib CCLE 0.0025 8.0000
PK-1 Tanespimycin CCLE 0.0025 8.0000
PK-1 TKI258 CCLE 0.0025 8.0000
PK-1 Topotecan CCLE 0.0025 8.0000
PK-1 ZD-6474 CCLE 0.0025 8.0000

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Drugs with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Drugs with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Drugs with highest and lowest AUC