Cell Line : MEC-1

Cellosaurus Index : CVCL_1870
Cellosaurus ID : MEC-1

CCLE Name : MEC1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE

Cancer Type : haematopoietic_and_lymphoid_tissue
Dataset : All

Drug Response Information

Click to show/hide information cards below or download all drug response information.

           

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including cell line name, drug name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Cellosaurus ID Drug Name Original Dataset(s) Min Dose Max Dose Dose-response
MEC-1 AEW541 CCLE 0.0025 8.0000
MEC-1 Crizotinib CCLE 0.0025 8.0000
MEC-1 Erlotinib CCLE 0.0025 8.0000
MEC-1 Irinotecan CCLE 0.0025 8.0000
MEC-1 L-685458 CCLE 0.0025 8.0000
MEC-1 Lapatinib CCLE 0.0025 8.0000
MEC-1 LBW242 CCLE 0.0025 8.0000
MEC-1 Nilotinib CCLE 0.0025 8.0000
MEC-1 Nutlin-3a CCLE 0.0025 8.0000
MEC-1 NVP-TAE684 CCLE 0.0025 8.0000
MEC-1 Paclitaxel CCLE 0.0025 8.0000
MEC-1 Palbociclib CCLE 0.0025 8.0000
MEC-1 Panobinostat CCLE 0.0025 8.0000
MEC-1 PD0325901 CCLE 0.0025 8.0000
MEC-1 PHA-665752 CCLE 0.0025 8.0000
MEC-1 PLX-4720 CCLE 0.0025 8.0000
MEC-1 RAF265 CCLE 0.0025 8.0000
MEC-1 Saracatinib CCLE 0.0025 8.0000
MEC-1 Selumetinib CCLE 0.0025 8.0000
MEC-1 Sorafenib CCLE 0.0025 8.0000
MEC-1 Tanespimycin CCLE 0.0025 8.0000
MEC-1 TKI258 CCLE 0.0025 8.0000
MEC-1 Topotecan CCLE 0.0025 8.0000
MEC-1 ZD-6474 CCLE 0.0025 8.0000

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Drugs with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Drugs with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Drugs with highest and lowest AUC