Cell Line : 1321N1

Cellosaurus Index : CVCL_0110
Cellosaurus ID : 1321N1

CCLE Name : 1321N1_CENTRAL_NERVOUS_SYSTEM
CTRP2 Name : 1321N1

Cancer Type : central_nervous_system
Dataset : All

Drug Response Information

Click to show/hide information cards below or download all drug response information.

           

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including cell line name, drug name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Cellosaurus ID Drug Name Original Dataset(s) Min Dose Max Dose Dose-response
1321N1 AEW541 CCLE 0.0025 8.0000
1321N1 Crizotinib CCLE 0.0025 8.0000
1321N1 Erlotinib CCLE 0.0025 8.0000
1321N1 L-685458 CCLE 0.0025 8.0000
1321N1 Lapatinib CCLE 0.0025 8.0000
1321N1 LBW242 CCLE 0.0025 8.0000
1321N1 Nutlin-3a CCLE 0.0025 8.0000
1321N1 NVP-TAE684 CCLE 0.0025 8.0000
1321N1 Paclitaxel CCLE 0.0025 8.0000
1321N1 Panobinostat CCLE 0.0025 8.0000
1321N1 PD0325901 CCLE 0.0025 8.0000
1321N1 PHA-665752 CCLE 0.0025 8.0000
1321N1 PLX-4720 CCLE 0.0025 8.0000
1321N1 RAF265 CCLE 0.0025 8.0000
1321N1 Saracatinib CCLE 0.0025 8.0000
1321N1 Selumetinib CCLE 0.0025 8.0000
1321N1 Sorafenib CCLE 0.0025 8.0000
1321N1 Tanespimycin CCLE 0.0025 8.0000
1321N1 TKI258 CCLE 0.0025 8.0000
1321N1 Topotecan CCLE 0.0025 8.0000
1321N1 ZD-6474 CCLE 0.0025 8.0000

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Drugs with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Drugs with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Drugs with highest and lowest AUC