Reveal integrative dose-response information
- CREAMMIST is an integrated cancer drug sensitivity database for in vitro pharmacogenomics analysis, providing an integrative dose-response curve across five widely used cancer cell-line drug-response datasets (CCLE, GDSC1, GDSC2, CTRP1, CTRP2).
- Dose-response values are systematically integrated using the Bayesian framework to obtain an integrative dose-response curve.
- Users can utilize easy-to-use statistics for various downstream analyses such as identifying biomarkers, selecting drug concentrations for their experiments, or training a more robust machine learning model.