Drug : Brd-K30748066

CTRP2 Name : BRD-K30748066

Dataset : All
Synonyms :
Targets : CDK9
Pathways : inhibitor of CDK9

Information Cards

Click to show/hide information cards below or download all drug response information.

           
     

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including drug name, cell line name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Drug name Cellosaurus ID Original Dataset(s) Min Dose Max Dose Dose-response
BRD-K30748066 KE-39 CTRP2 0.0020 66.0000
BRD-K30748066 DMS454 CTRP2 0.0020 66.0000
BRD-K30748066 GCT CTRP2 0.0020 66.0000
BRD-K30748066 HCC2935 CTRP2 0.0020 66.0000
BRD-K30748066 HOP-62 CTRP2 0.0020 66.0000
BRD-K30748066 NCI-H747 CTRP2 0.0020 66.0000
BRD-K30748066 OVCAR-5 CTRP2 0.0020 66.0000
BRD-K30748066 SF268 CTRP2 0.0020 66.0000
BRD-K30748066 SF539 CTRP2 0.0020 66.0000
BRD-K30748066 U-251MG CTRP2 0.0020 66.0000
BRD-K30748066 DMS53 CTRP2 0.0020 66.0000
BRD-K30748066 HEC-1-A CTRP2 0.0020 66.0000
BRD-K30748066 IGR-37 CTRP2 0.0020 66.0000
BRD-K30748066 KNS-62 CTRP2 0.0020 66.0000
BRD-K30748066 NCI-H1563 CTRP2 0.0020 66.0000
BRD-K30748066 OC314 CTRP2 0.0020 66.0000
BRD-K30748066 UO-31 CTRP2 0.0020 66.0000
BRD-K30748066 BICR56 CTRP2 0.0020 66.0000
BRD-K30748066 CAL-33 CTRP2 0.0020 66.0000
BRD-K30748066 CALU-1 CTRP2 0.0020 66.0000
BRD-K30748066 CAPAN-2 CTRP2 0.0020 66.0000
BRD-K30748066 DMS114 CTRP2 0.0020 66.0000
BRD-K30748066 EKVX CTRP2 0.0020 66.0000
BRD-K30748066 HCC1438 CTRP2 0.0020 66.0000
BRD-K30748066 HCT8 CTRP2 0.0020 66.0000
BRD-K30748066 HOP-92 CTRP2 0.0020 66.0000
BRD-K30748066 KYM-1 CTRP2 0.0020 66.0000
BRD-K30748066 KYSE-30 CTRP2 0.0020 66.0000
BRD-K30748066 KYSE-510 CTRP2 0.0020 66.0000
BRD-K30748066 L-428 CTRP2 0.0020 66.0000
BRD-K30748066 MDA-MB-361 CTRP2 0.0020 66.0000
BRD-K30748066 MFE-296 CTRP2 0.0020 66.0000
BRD-K30748066 NU-DHL-1 CTRP2 0.0020 66.0000
BRD-K30748066 SNB-75 CTRP2 0.0020 66.0000
BRD-K30748066 SNU-216 CTRP2 0.0020 66.0000
BRD-K30748066 BICR16 CTRP2 0.0020 66.0000
BRD-K30748066 F-36P CTRP2 0.0020 66.0000
BRD-K30748066 JJN-3 CTRP2 0.0020 66.0000
BRD-K30748066 KASUMI-2 CTRP2 0.0020 66.0000
BRD-K30748066 KG-1-C CTRP2 0.0020 66.0000
BRD-K30748066 KMS-20 CTRP2 0.0020 66.0000
BRD-K30748066 KYSE-150 CTRP2 0.0020 66.0000
BRD-K30748066 OCI-AML-5 CTRP2 0.0020 66.0000
BRD-K30748066 PANC08.13 CTRP2 0.0020 66.0000
BRD-K30748066 SNU-601 CTRP2 0.0020 66.0000
BRD-K30748066 SNU-C4 CTRP2 0.0020 66.0000
BRD-K30748066 T-47D CTRP2 0.0020 66.0000
BRD-K30748066 T84 CTRP2 0.0020 66.0000
BRD-K30748066 TE-14 CTRP2 0.0020 66.0000
BRD-K30748066 U266B1 CTRP2 0.0020 66.0000
BRD-K30748066 42-MG-BA CTRP2 0.0020 66.0000
BRD-K30748066 BT139 CTRP2 0.0020 66.0000
BRD-K30748066 BT159 CTRP2 0.0020 66.0000
BRD-K30748066 BT187 CTRP2 0.0020 66.0000
BRD-K30748066 BT228 CTRP2 0.0020 66.0000
BRD-K30748066 BT231 CTRP2 0.0020 66.0000
BRD-K30748066 BT239 CTRP2 0.0020 66.0000
BRD-K30748066 BT-474 CTRP2 0.0020 66.0000
BRD-K30748066 COV434 CTRP2 0.0020 66.0000
BRD-K30748066 DND-41 CTRP2 0.0020 66.0000
BRD-K30748066 G-292CLONEA141B1 CTRP2 0.0020 66.0000
BRD-K30748066 HCC2218 CTRP2 0.0020 66.0000
BRD-K30748066 HS766T CTRP2 0.0020 66.0000
BRD-K30748066 KMRC-3 CTRP2 0.0020 66.0000
BRD-K30748066 M-07E CTRP2 0.0020 66.0000
BRD-K30748066 NCI-H1651 CTRP2 0.0020 66.0000
BRD-K30748066 SK-BR-3 CTRP2 0.0020 66.0000
BRD-K30748066 SNU-1033 CTRP2 0.0020 66.0000
BRD-K30748066 A-204 CTRP2 0.0020 66.0000
BRD-K30748066 AML-193 CTRP2 0.0020 66.0000
BRD-K30748066 HGC-27 CTRP2 0.0020 66.0000
BRD-K30748066 HS578BST CTRP2 0.0020 66.0000
BRD-K30748066 HS688(A).T CTRP2 0.0020 66.0000
BRD-K30748066 NCI-H1793 CTRP2 0.0020 66.0000
BRD-K30748066 SCC-4 CTRP2 0.0020 66.0000
BRD-K30748066 SK-ES-1 CTRP2 0.0020 66.0000
BRD-K30748066 HS888.T CTRP2 0.0020 66.0000
BRD-K30748066 SAOS-2 CTRP2 0.0020 66.0000
BRD-K30748066 U-BLC1 CTRP2 0.0020 66.0000
BRD-K30748066 BT248 CTRP2 0.0020 66.0000
BRD-K30748066 NCI-H1694 CTRP2 0.0020 66.0000
BRD-K30748066 HS822.T CTRP2 0.0020 66.0000
BRD-K30748066 HS940.T CTRP2 0.0020 66.0000
BRD-K30748066 KMBC-2 CTRP2 0.0020 66.0000
BRD-K30748066 RCC10RGB CTRP2 0.0020 66.0000
BRD-K30748066 SK-N-BE(2) CTRP2 0.0020 66.0000
BRD-K30748066 AU565 CTRP2 0.0020 66.0000
BRD-K30748066 COLO320 CTRP2 0.0020 66.0000
BRD-K30748066 PANC10.05 CTRP2 0.0020 66.0000
BRD-K30748066 BT131 CTRP2 0.0020 66.0000
BRD-K30748066 BT147 CTRP2 0.0020 66.0000
BRD-K30748066 BT172 CTRP2 0.0020 66.0000
BRD-K30748066 BT216 CTRP2 0.0020 66.0000
BRD-K30748066 BT232 CTRP2 0.0020 66.0000
BRD-K30748066 BT245 CTRP2 0.0020 66.0000
BRD-K30748066 BT286 CTRP2 0.0020 66.0000
BRD-K30748066 BT320 CTRP2 0.0020 66.0000
BRD-K30748066 BT328 CTRP2 0.0020 66.0000
BRD-K30748066 BT330 CTRP2 0.0020 66.0000
BRD-K30748066 BT333 CTRP2 0.0020 66.0000
BRD-K30748066 BT340 CTRP2 0.0020 66.0000
BRD-K30748066 BT359 CTRP2 0.0020 66.0000
BRD-K30748066 BT416 CTRP2 0.0020 66.0000
BRD-K30748066 BT422 CTRP2 0.0020 66.0000
BRD-K30748066 BT428 CTRP2 0.0020 66.0000
BRD-K30748066 BT440 CTRP2 0.0020 66.0000
BRD-K30748066 BT444 CTRP2 0.0020 66.0000
BRD-K30748066 BT482 CTRP2 0.0020 66.0000
BRD-K30748066 BT504 CTRP2 0.0020 66.0000
BRD-K30748066 2004 CTRP2 0.0020 66.0000
BRD-K30748066 ASKA-SS CTRP2 0.0020 66.0000
BRD-K30748066 BT-12 CTRP2 0.0020 66.0000
BRD-K30748066 BT-16 CTRP2 0.0020 66.0000
BRD-K30748066 SYO-1 CTRP2 0.0020 66.0000
BRD-K30748066 TM87-16 CTRP2 0.0020 66.0000
BRD-K30748066 TTC-709 CTRP2 0.0020 66.0000
BRD-K30748066 YAMATO-SS CTRP2 0.0020 66.0000

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Cell lines with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Cell lines with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Cell lines with highest and lowest AUC

Associated Genes (Mutation)

Genes with the largest and lowest Racksum’s effect sizes, calculated by comparing IC50 between the mutant and wide type cell lines using cell lines from pancan data.

Associated Genes (Gene Expression)

Genes with the highest and lowest Spearman correlations, calculated by comparing gene expression and IC50 across cell lines from pancan data.