Cell Line vs Drug : HCC1428 vs Podophyllotoxin bromide

Cellosaurus ID : HCC1428
Drug Name : Podophyllotoxin bromide
Dataset : All (GDSC2)

Information Cards

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Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Dose Response Relationship

Each dot indicates drug response at different dosages, and each color represents the original datasets. A pink line is an integrated dose-response curve. Grey lines represent alternative dose-response curves resulting from a Bayesian curve fitting. A horizontal dashed line represents 50% cell inhibitions. A vertical dashed line represents IC50.

IC50 Distribution

Distribution of drug dosage needed to inhibit the cells by 50%. Dashed lines represent 95% high-density interval (HDI).

Drug Sensitivity Scores
IC50 1.4785 log2 Concentration (μM)
IC90 3.0526 log2 Concentration (μM)
AUC 0.8594 %
EC50 -0.5407 log2 Concentration (μM)
Einf 0.1127 cell death rate