Cell Line vs Drug : SKM-1 vs AZD5363

Cellosaurus ID : SKM-1
Drug Name : AZD5363
Dataset : All (GDSC2)

Information Cards

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Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Dose Response Relationship

Each dot indicates drug response at different dosages, and each color represents the original datasets. A pink line is an integrated dose-response curve. Grey lines represent alternative dose-response curves resulting from a Bayesian curve fitting. A horizontal dashed line represents 50% cell inhibitions. A vertical dashed line represents IC50.

IC50 Distribution

Distribution of drug dosage needed to inhibit the cells by 50%. Dashed lines represent 95% high-density interval (HDI).

Drug Sensitivity Scores
IC50 3.8952 log2 Concentration (μM)
IC90 9.1162 log2 Concentration (μM)
AUC 13.5436 %
EC50 0.8876 log2 Concentration (μM)
Einf 0.4400 cell death rate