Cell Line vs Drug : MFM-223 vs PI3Ka_4409

Cellosaurus ID : MFM-223
Drug Name : PI3Ka_4409
Dataset : All (GDSC1)

Information Cards

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Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Dose Response Relationship

Each dot indicates drug response at different dosages, and each color represents the original datasets. A pink line is an integrated dose-response curve. Grey lines represent alternative dose-response curves resulting from a Bayesian curve fitting. A horizontal dashed line represents 50% cell inhibitions. A vertical dashed line represents IC50.

IC50 Distribution

Distribution of drug dosage needed to inhibit the cells by 50%. Dashed lines represent 95% high-density interval (HDI).

Drug Sensitivity Scores
IC50 2.4391 log2 Concentration (μM)
IC90 5.3711 log2 Concentration (μM)
AUC 17.8960 %
EC50 1.4929 log2 Concentration (μM)
Einf 0.6596 cell death rate