Cell Line vs Drug : PE-CA-PJ15 vs Nutlin-3a

Cellosaurus ID : PE-CA-PJ15
Drug Name : Nutlin-3a
Dataset : All (GDSC1,GDSC2,CTRP2)

Information Cards

Click to show/hide information cards below or download the experimental information.

        

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

:

Dose Response Relationship

Each dot indicates drug response at different dosages, and each color represents the original datasets. A pink line is an integrated dose-response curve. Grey lines represent alternative dose-response curves resulting from a Bayesian curve fitting. A horizontal dashed line represents 50% cell inhibitions. A vertical dashed line represents IC50.

IC50 Distribution

Distribution of drug dosage needed to inhibit the cells by 50%. Dashed lines represent 95% high-density interval (HDI).

Drug Sensitivity Scores
IC50 6.9184 log2 Concentration (μM)
IC90 10.6428 log2 Concentration (μM)
AUC 8.8983 %
EC50 5.2567 log2 Concentration (μM)
Einf 0.5457 cell death rate