Biomarker information

Drug-gene associations based on IC50 and mutation (or gene expression) profile. IC50 value was estimated using the integrated dose-response curve.

Gene : SLC4A3
Drug Name : BRD-K61166597
Cancer type : pancan

Association Information

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Drug-gene association (IC50 vs mutation)

Ranksum’s effect size was calculated by comparing IC50 between mutant and wide-type cell lines (more detail).

Drug-gene association (IC50 vs gene expression)

Spearman correlation was calculated by comparing IC50 and gene expression (TMM) across cell lines (more detail).

IC50 vs mutation

Relationships between IC50 and mutation profiles base on "All" dataset.

IC50 vs gene expression

Relationships between IC50 and gene expression profiles base on "All" dataset.