API

CREAMMIST provides API for accessing the different kinds of data such as cell lines, drugs, dose-response relationships, dose-response curves, and statistics.

GET api/celllines

List of available cell lines and their description

https://creammist.mtms.dev/api/celllines

GET api/celllines/{cellosaurus_id}

List of drugs tested for a specific cell line

https://creammist.mtms.dev/api/celllines/1321N1

GET api/cancertypes

List of available cancer types

https://creammist.mtms.dev/api/cancertypes

GET api/cancertypes/{cancer_type}

List of cell lines for a specific cancer type

https://creammist.mtms.dev/api/cancertypes/stomach

GET api/experiments/{cellosaurus_id}/
{standard_drug_name}

Dose-response information for a given pair of cell line and drug.

https://creammist.mtms.dev/api/experiments/1321N1/Lapatinib

GET api/drugs

List of available drugs and their description

https://creammist.mtms.dev/api/drugs

GET api/drugs/{standard_drug_name}

List of cell lines tested for a specific drug

https://creammist.mtms.dev/api/drugs/Lapatinib

GET api/genes

List of available genes

https://creammist.mtms.dev/api/genes

GET api/biomarker/{exp|mut}/{cancer_type}/gene/
{gene}/{pos|neg}/{n_top}

List of top associated drugs given a gene name. The list is ranked by either Spearman correlation (i.e., gene expression vs IC50) or Ranksum’s effect size (i.e., IC50 of wild type vs mutant).

https://creammist.mtms.dev/api/biomarker/exp/pancan/gene/EGFR/pos/10

GET api/biomarker/{exp|mut}/{cancer_type}/drug/
{standard_drug_name}/{pos|neg}/{n_top}

List of top associated genes given a drug name. The list is ranked by either Spearman correlation (i.e., gene expression vs IC50) or Ranksum’s effect size (i.e., IC50 of wild type vs mutant).

https://creammist.mtms.dev/api/biomarker/exp/pancan/drug/Lapatinib/pos/10

GET api/biomarker/{exp|mut}/{cancer_type}/info/
{gene}/{standard_drug_name}

Association information for a given pair of drug and gene.

https://creammist.mtms.dev/api/biomarker/mut/pancan/info/EGFR/Lapatinib

GET api/mutation/{cellosaurus_id}

A mutation profile of a given cell line

https://creammist.mtms.dev/api/mutation/A-172

GET api/expression/{cellosaurus_id}

A gene expression profile (TMM) of a given cell line

https://creammist.mtms.dev/api/expression/A-172